Catherine Fitting

Cytokine Profiles of AIDS Patients Are Similar to Those of Mice with Disseminated Cryptococcus neoformans Infection

Lortholary, Olivier, Improvisi, Luce, Rayhane, Naima, Gray, Francoise, Fitting, Catherine, Cavaillon, Jean Marc, ...

Cryptococcosis is an hematogenously disseminated meningoencephalitis during which the relationship between the disease severity and the immune response remains unclear. We thus analyzed, by...

Administration of Endotoxin Associated with Lipopolysaccharide Tolerance Protects Mice against Fungal Infection

Rayhane, Naïma, Fitting, Catherine, Lortholary, Olivier, Dromer, Francoise, Cavaillon, Jean-Marc

Lipopolysaccharide (LPS) pretreatment of mice resulted in a significantly enhanced survival after disseminated Cryptococcus neoformans infection. The survival was associated with reduced fungal...

Pyrogenicity and Cytokine-Inducing Properties of Streptococcus pyogenes Superantigens: Comparative Study of Streptococcal Mitogenic Exotoxin Z and Pyrogenic Exotoxin A

Müller-Alouf, Heide, Proft, Thomas, Zollner, Thomas M., Gerlach, Dieter, Champagne, Eric, Desreumaux, Pierre, ...

Streptococcal mitogenic exotoxin Z (SMEZ), a superantigen derived from Streptococcus pyogenes, provoked expansion of human lymphocytes expressing the Vβ 2, 4, 7 and 8 motifs of T-cell receptor. SMEZ...

Bordetella pertussis Adenylate Cyclase-Hemolysin Induces Interleukin-6 Secretion by Human Tracheal Epithelial Cells

Bassinet, Laurence, Fitting, Catherine, Housset, Bruno, Cavaillon, Jean-Marc, Guiso, Nicole

After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the...

Cytokine Profiles of AIDS Patients Are Similar to Those of Mice with Disseminated Cryptococcus neoformans Infection

Lortholary, Olivier, Improvisi, Luce, Rayhane, Naima, Gray, Francoise, Fitting, Catherine, Cavaillon, Jean Marc, ...

Cryptococcosis is an hematogenously disseminated meningoencephalitis during which the relationship between the disease severity and the immune response remains unclear. We thus analyzed, by...

Administration of Endotoxin Associated with Lipopolysaccharide Tolerance Protects Mice against Fungal Infection

Rayhane, Naïma, Fitting, Catherine, Lortholary, Olivier, Dromer, Francoise, Cavaillon, Jean-Marc

Lipopolysaccharide (LPS) pretreatment of mice resulted in a significantly enhanced survival after disseminated Cryptococcus neoformans infection. The survival was associated with reduced fungal...

Pyrogenicity and Cytokine-Inducing Properties of Streptococcus pyogenes Superantigens: Comparative Study of Streptococcal Mitogenic Exotoxin Z and Pyrogenic Exotoxin A

Müller-Alouf, Heide, Proft, Thomas, Zollner, Thomas M., Gerlach, Dieter, Champagne, Eric, Desreumaux, Pierre, ...

Streptococcal mitogenic exotoxin Z (SMEZ), a superantigen derived from Streptococcus pyogenes, provoked expansion of human lymphocytes expressing the Vβ 2, 4, 7 and 8 motifs of T-cell receptor. SMEZ...

Bordetella pertussis Adenylate Cyclase-Hemolysin Induces Interleukin-6 Secretion by Human Tracheal Epithelial Cells

Bassinet, Laurence, Fitting, Catherine, Housset, Bruno, Cavaillon, Jean-Marc, Guiso, Nicole

After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the...

Contribution of Phagocytosis and Intracellular Sensing for Cytokine Production by Staphylococcus aureus-Activated Macrophages▿

Kapetanovic, Ronan, Nahori, Marie-Anne, Balloy, Viviane, Fitting, Catherine, Philpott, Dana J., Cavaillon, Jean-Marc, ...

Toll-like receptors (TLRs) are involved in the sensing of microbially derived compounds. We analyzed the contribution of these receptors to cytokine production by macrophages following stimulation...

Simple Method for Repurification of Endotoxins for Biological Use▿

Tirsoaga, Alina, Novikov, Alexey, Adib-Conquy, Minou, Werts, Catherine, Fitting, Catherine, Cavaillon, Jean-Marc, ...

A method for obtaining highly purified endotoxin (lipopolysaccharide [LPS]) in a few hours by repurification of commercial or laboratory preparations was devised. It avoids the use of phenol, which...

Clostridium sordellii Lethal Toxin Kills Mice by Inducing a Major Increase in Lung Vascular Permeability

Geny, Blandine, Khun, Huot, Fitting, Catherine, Zarantonelli, Leticia, Mazuet, Christelle, Cayet, Nadège, ...

When intraperitoneally injected into Swiss mice, Clostridium sordellii lethal toxin reproduces the fatal toxic shock syndrome observed in humans and animals after natural infection. This animal model...