Catherine Q. Nie

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines (2008)

Van Aelst, Ilse, Martens, Erik, ...

Cerebral malaria (CM) results from the binding of infected erythrocytes and leukocytes to brain endothelia. The precise mechanisms underlying lymphocyte recruitment and activation in CM remain...

Blood-stage Plasmodium infection induces CD+ T lymphocytes to parasite-expressed antigens, largely regulated by CDα+ dendritic cells (2008)

Lundie, Rachel J., Davey, Gayle M., Nie, Catherine Q., Hansen, Diana S., Lau, Lei Shong, ...

Although CD8+ T cells do not contribute to protection against the blood stage of Plasmodium infection, there is mounting evidence that they are principal mediators of murine experimental cerebral...

CD4+ CD25+ Regulatory T Cells Suppress CD4+ T-Cell Function and Inhibit the Development of Plasmodium berghei-Specific TH1 Responses Involved in Cerebral Malaria Pathogenesis▿

Nie, Catherine Q., Bernard, Nicholas J., Schofield, Louis, Hansen, Diana S.

The infection of mice with Plasmodium berghei ANKA constitutes the best available mouse model for human Plasmodium falciparum-mediated cerebral malaria, a devastating neurological syndrome that kills...

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8α+ dendritic cells

Lundie, Rachel J., Davey, Gayle M., Nie, Catherine Q., Hansen, Diana S., Lau, Lei Shong, ...

Although CD8+ T cells do not contribute to protection against the blood stage of Plasmodium infection, there is mounting evidence that they are principal mediators of murine experimental cerebral...

IP-10-Mediated T Cell Homing Promotes Cerebral Inflammation over Splenic Immunity to Malaria Infection

Nie, Catherine Q., Bernard, Nicholas J., Norman, M. Ursula, Amante, Fiona H., Lundie, Rachel J., Crabb, Brendan S., ...

Plasmodium falciparum malaria causes 660 million clinical cases with over 2 million deaths each year. Acquired host immunity limits the clinical impact of malaria infection and provides protection...