Catriona McKay

Jak3 Selectively Regulates Bax and Bcl-2 Expression To Promote T-Cell Development

Wen, Renren, Wang, Demin, McKay, Catriona, Bunting, Kevin D., Marine, Jean-Christophe, Vanin, Elio F., ...

Jak3-deficient mice display vastly reduced numbers of lymphoid cells. Thymocytes and peripheral T cells from Jak3-deficient mice have a high apoptotic index, suggesting that Jak3 provides survival...

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

Piekorz, Roland P., Hoffmeyer, Angelika, Duntsch, Christopher D., McKay, Catriona, Nakajima, Hideaki, Sexl, Veronika, ...

TACC3 is a centrosomal/mitotic spindle-associated protein that is highly expressed in a cell cycle-dependent manner in hematopoietic lineage cells. During embryonic development, TACC3 is expressed in...

The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis

Zang, Heesuk, Sato, Ken, Nakajima, Hideaki, McKay, Catriona, Ney, Paul A., Ihle, James N.

The erythropoietin receptor (EpoR) is required for the proliferation and survival of committed erythroid lineage cells. Previous studies have utilized receptor mutations to show the requirement for...

c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

Baudino, Troy A., McKay, Catriona, Pendeville-Samain, Helene, Nilsson, Jonas A., Maclean, Kirsteen H., White, Elsie L., ...

c-Myc promotes cell growth and transformation by ill-defined mechanisms. c-myc−/− mice die by embryonic day 10.5 (E10.5) with defects in growth and in cardiac and neural development. Here we...

Jak3 Selectively Regulates Bax and Bcl-2 Expression To Promote T-Cell Development

Wen, Renren, Wang, Demin, McKay, Catriona, Bunting, Kevin D., Marine, Jean-Christophe, Vanin, Elio F., ...

Jak3-deficient mice display vastly reduced numbers of lymphoid cells. Thymocytes and peripheral T cells from Jak3-deficient mice have a high apoptotic index, suggesting that Jak3 provides survival...

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

Piekorz, Roland P., Hoffmeyer, Angelika, Duntsch, Christopher D., McKay, Catriona, Nakajima, Hideaki, Sexl, Veronika, ...

TACC3 is a centrosomal/mitotic spindle-associated protein that is highly expressed in a cell cycle-dependent manner in hematopoietic lineage cells. During embryonic development, TACC3 is expressed in...

The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis

Zang, Heesuk, Sato, Ken, Nakajima, Hideaki, McKay, Catriona, Ney, Paul A., Ihle, James N.

The erythropoietin receptor (EpoR) is required for the proliferation and survival of committed erythroid lineage cells. Previous studies have utilized receptor mutations to show the requirement for...

c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

Baudino, Troy A., McKay, Catriona, Pendeville-Samain, Helene, Nilsson, Jonas A., Maclean, Kirsteen H., White, Elsie L., ...

c-Myc promotes cell growth and transformation by ill-defined mechanisms. c-myc−/− mice die by embryonic day 10.5 (E10.5) with defects in growth and in cardiac and neural development. Here we...