Cecilia D'Alterio

Drosophila melanogaster Cad99C, the orthologue of human Usher cadherin PCDH15, regulates the length of microvilli

D'Alterio, Cecilia, Tran, Dao D.D., Yeung, Maggie W.Y. Au, Hwang, Michael S.H., Li, Michelle A., Arana, Claudia J., ...

Actin-based protrusions can form prominent structures on the apical surface of epithelial cells, such as microvilli. Several cytoplasmic factors have been identified that control the dynamics of...

Drosophila germ-line modulation of insulin signaling and lifespan

Flatt, Thomas, Min, Kyung-Jin, D'Alterio, Cecilia, Villa-Cuesta, Eugenia, Cumbers, John, Lehmann, Ruth, ...

Ablation of germ-line precursor cells in Caenorhabditis elegans extends lifespan by activating DAF-16, a forkhead transcription factor (FOXO) repressed by insulin/insulin-like growth factor (IGF)...