Cecilia Lundberg

Identification of proteins involved in neural progenitor cell targeting of gliomas (2009)

Staflin, Karin, Zuchner, Thole, Honeth, Gabriella, Darabi, Anna, Lundberg, Cecilia

Abstract Background Glioblastoma are highly aggressive tumors with an average survival time of 12 months with currently available treatment. We have previously shown that specific embryonic neural...

Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants (2009)

Nielsen, Troels T, Jakobsson, Johan, Rosenqvist, Nina, Lundberg, Cecilia

Abstract Background Lentiviral vectors hold great promise as gene transfer vectors in gene therapeutic settings. However, problems related to the risk of insertional mutagenesis, transgene silencing...

Dagens kvinnliga polis - androgyn? (2007)

Lundberg, Cecilia, Johansson, Teresia

Uppsatsen ”Dagens kvinnliga polis - androgyn? ” handlar om hur kvinnliga poliserupplever sin yrkesroll utifrån deras erfarenheter och syn på begreppen allmänheten, genus, egenskaper och...

Conceptualizing the Baltic Sea Ecosystem: An Interdisciplinary Tool for Environmental Decision Making (2005)

Cecilia Lundberg

There is an increasing call for stronger interdisciplinary studies in the Baltic Sea to find solutions to the environmental and social problems associated with eutrophication. Cooperation between...

Eutrophication in the Baltic Sea from area-specific biological effects to interdisciplinary consequences / (2005)

Lundberg, Cecilia.

Svensk sammanfattning: Övergödningen i Östersjön : småskaliga biologiska effekter ger tvärvetenskapliga följder.

Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector. (2004)

Jakobsson, Johan, Georgievska, Biljana, Ericson, Cecilia, Lundberg, Cecilia

The ability to regulate transgene expression will be crucial for development of gene therapy to the brain. The most commonly used systems are based on a transactivator in combination with a drug,...

Long-Term Survival and Glial Differentiation of the Brain-Derived Precursor Cell Line RN33B after Subretinal Transplantation to Adult Normal Rats. (2002)

Wojciechowski, Anita Blixt, Englund, Ulrica, Lundberg, Cecilia, Warfvinge, Karin

The potential use of in vitro-expanded precursor cells or cell lines in repair includes transplantation of such cells for cell replacement purposes and the activation of host cells to provide...

Ex vivo and in vitro studies of transgene expression in rat astrocytes transduced with lentiviral vectors. (2002)

Ericson, Cecilia, Wictorin, Klas, Lundberg, Cecilia

Implantation of cells genetically modified to express therapeutic genes into the brain has been proposed as a potential treatment for neurodegenerative diseases. In the current study embryonic...

Transplantation of human neural progenitor cells into the neonatal rat brain: extensive migration and differentiation with long-distance axonal projections. (2002)

Englund, Ulrica, Fricker-Gates, Rosemary A, Lundberg, Cecilia, Björklund, Anders, Wictorin, Klas

Here we examined the ability of human neural progenitors from the embryonic forebrain, expanded for up to a year in culture in the presence of growth factors, to respond to environmental signals...

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. (2002)

Kirik, Deniz, Rosenblad, Carl, Burger, Corinna, Lundberg, Cecilia, Johansen, Teit E, Muzyczka, Nicholas, ...

Recombinant adeno-associated viral vectors display efficient tropism for transduction of the dopamine neurons of the substantia nigra. Taking advantage of this unique property of recombinant...

Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector. (2002)

Georgievska, Biljana, Kirik, Deniz, Rosenblad, Carl, Lundberg, Cecilia, Björklund, Anders

We used a recombinant lentiviral vector (rLV) for gene delivery of GDNF to the striatum, and assessed its neuroprotective effects in the intrastriatal 6-hydroxydopamine (6-OHDA) lesion model.The...

Differentiation of the RN33B Cell Line into Forebrain Projection Neurons after Transplantation into the Neonatal Rat Brain. (2002)

Lundberg, Cecilia, Englund, Ulrica, Trono, Didier, Björklund, Anders, Wictorin, Klas

The rat neural cell line RN33B has a remarkable ability to undergo region-specific neuronal differentiation after transplantation into the CNS. To further study its neurogenic properties in vivo, we...

Subretinal Transplantation of Brain-derived Precursor Cells to Young RCS Rats Promotes Photoreceptor Cell Survival( small star, filled). (2002)

Blixt Wojciechowski, Anita, Englund, Ulrica, Lundberg, Cecilia, Wictorin, Klas, Warfvinge, Karin

The potential use of in vitro-expanded precursor cells or cell lines in brain repair includes transplantation of such cells for cell replacement purposes and the activation of host cells to provide...

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. (2002)

Lotharius, Julie, Barg, Sebastian, Wiekop, Pia, Lundberg, Cecilia, Raymon, Heather K., Brundin, Patrik

Mutations in alpha-synuclein have been linked to rare, autosomal dominant forms of Parkinsons disease. Despite its ubiquitous expression, mutant alpha-synuclein primarily leads to the loss of...

Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain. (2002)

Lundberg, Cecilia, Englund, Ulrica, Trono, Didier, Björklund, Anders, Wictorin, Klas

The rat neural cell line RN33B has a remarkable ability to undergo region-specific neuronal differentiation after transplantation into the CNS. To further study its neurogenic properties in vivo, we...

Use of neural progenitor cell lines and astrocytes for transplantation and gene transfer to the CNS. (1996)

Lundberg, Cecilia

Intracerebral neuronal transplantation have been shown to ameliorate symptoms of brain dysfunction in both animals models and Parkinson's disease, although problems still remain. The newly introduced...

Use of neural progenitor cell lines and astrocytes for transplantation and gene transfer to the CNS (1996)

Lundberg, Cecilia

Intracerebral neuronal transplantation have been shown to ameliorate symptoms of brain dysfunction in both animals models and Parkinson's disease, although problems still remain. The newly introduced...