Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly (2006)
Nolwenn Jouvenet, Cameron Bess, Marc C. Johnson, Cesar A. Virgen, Sanford M. Simon, ...
Recently proposed models that have gained wide acceptance posit that HIV-1 virion morphogenesis is initiated by targeting the major structural protein (Gag) to late endosomal membranes. Thereafter,...
Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly
Jouvenet, Nolwenn, Neil, Stuart J. D, Bess, Cameron, Johnson, Marc C, Virgen, Cesar A, Simon, Sanford M, ...
Recently proposed models that have gained wide acceptance posit that HIV-1 virion morphogenesis is initiated by targeting the major structural protein (Gag) to late endosomal membranes. Thereafter,...
Antiretroviral Activity and Vif Sensitivity of Rhesus Macaque APOBEC3 Proteins▿
Virgen, Cesar A., Hatziioannou, Theodora
The inability of human immunodeficiency virus type 1(HIV-1) to replicate in rhesus macaque cells is in part due to the failure of HIV-1 Vif to counteract the restriction factor APOBEC3G. However, in...
Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species
Virgen, Cesar A., Kratovac, Zerina, Bieniasz, Paul D., Hatziioannou, Theodora
The host range of retroviruses is influenced by antiviral proteins such as TRIM5, a restriction factor that recognizes and inactivates incoming retroviral capsids. Remarkably, in Owl monkeys (omk), a...
Primate Lentivirus Capsid Sensitivity to TRIM5 Proteins▿
Kratovac, Zerina, Virgen, Cesar A., Bibollet-Ruche, Frederick, Hahn, Beatrice H., Bieniasz, Paul D., Hatziioannou, Theodora
Mammalian cells express several factors that inhibit lentiviral infection and that have been under strong selective pressure. One of these factors, TRIM5, targets the capsid protein of incoming...