THE OPTIMAL ROS-BASED SYMMETRIC PHASE-ONLY FILTER FOR FINGERPRINT VERIFICATION (2009)
Xin Shuai, Chao Zhang, Pengwei Hao
Symmetric phase-only filter (SPOF) has been widely applied to image registration and recognition, and has been proved efficient for fingerprint verification. Fingerprint images have a characteristic...
Fingerprint Indexing Based on LAS Registration (2009)
Tong Liu, Chao Zhang, Pengwei Hao
Fingerprint indexing is an efficient technique that greatly improves the performance of fingerprint based person authentication systems by reducing the number of comparison. In this paper, we propose...
Sun, Liling, Dai, Xi, Zhang, Chao, Yi, Wei, Zheng, Lirong, Jiang, Zheng, ...
We discover a pressure induced quantum phase transition from the superconducting state to the non-superconducting Kondo screened phase associated with a 2% volume collapse in CeFeAsO0.7F0.3 through...
A Language of Suggestions for Program Parallelization (2009)
Zhang, Chao, Ding, Chen, Kelsey, Kirk, Bai, Tongxin, Gu, Xiaoming, Feng, Xiaobing
Coarse-grained task parallelism exists in sequential code and can be leveraged to boost the use of chip multi-processors. However, large tasks may execute thousands of lines of code and are often too...
Zhang, Chao, Yi, Wei, Sun, Liling, Lu, Wei, Dong, Xiaoli, Bai, Ligang, ...
We report studies of in-situ x-ray diffraction (XRD) and electronic properties on the single crystalline of Fe1.05Te compound under high pressure. The results demonstrated that the sample undergoes a...
Transmission resonance in a composite plasmonic structure (2009)
Yin, Xiao-gang, Huang, Cheng-ping, Wang, Qian-jin, Zhang, Chao, Zhu, Yong-yuan
The design, fabrication, and optical properties of a composite plasmonic structure, a two-dimentional array of split-ring resonators inserted into periodic square holes of a metal film, have been...
Chao Zhang, Yong Ren, Mei-Ming Luo
In the title compound, C25H35N32+·2Br−·H2O, the dihedral angles between the imidazole ring and the two outer benzene rings are 80.16 (16) and 69.40 (18)°. The...
Huisheng Zhang, Chao Zhang, Wei Wu
The batch split-complex backpropagation (BSCBP) algorithm for training complex-valued neural networks is considered. For constant learning rate, it is proved that the error function of BSCBP...
Sturm-Picone Comparison Theorem of Second-Order Linear Equations on Time Scales (2009)
This paper studies Sturm-Picone comparison theorem of second-order linear equations on time scales. We first establish Picone identity on time scales and obtain our main result by using it. Also, our...
This paper studies general coupled boundary value problems for second-order difference equations. Existence of eigenvalues is proved, numbers of their eigenvalues are calculated, and their...
Huisheng Zhang, Chao Zhang, Wei Wu
The batch split-complex backpropagation (BSCBP) algorithm for training complex-valued neural networks is considered. For constant learning rate, it is proved that the error function of BSCBP...
Sturm-Picone Comparison Theorem of Second-Order Linear Equations on Time Scales (2009)
This paper studies Sturm-Picone comparison theorem of second-order linear equations on time scales. We first establish Picone identity on time scales and obtain our main result by using it. Also, our...
This paper studies general coupled boundary value problems for second-order difference equations. Existence of eigenvalues is proved, numbers of their eigenvalues are calculated, and their...
Space Charge Formation in Epoxy Resin Including Various Nanofillers (2008)
Hajiyiannis , Alexis, Chen, George, Zhang, Chao, Stevens, Gary
It has been widely anticipated that the combination of recent advances in nanocomposites technology with traditional and novel resin systems may create materials with enhanced electrical, thermal and...
High pressure study on LaFeAsO with different Tc (2008)
Yi, Wei, Zhang, Chao, Sun, Liling, Ren, Zhi-an, Lu, Wei, Dong, Xiaoli, ...
We report studies on pressure dependence of superconducting transition temperature (Tc) of LaFeAsO, LaFeAs(O0.5F0.5) and LaFeAs(O0.89F0.11) samples. In-situ resistance measurements under high...
Kim, Joanne SM, Lilley, Brendan N, Zhang, Chao, Shokat, Kevan M, Sanes, Joshua R, Zhen, Mei
Abstract Background Neurons assemble into a functional network through a sequence of developmental processes including neuronal polarization and synapse formation. In Caenorhabditis elegans , the...
Peña-Castillo, Lourdes, Tasan, Murat, Myers, Chad L, Lee, Hyunju, Joshi, Trupti, Zhang, Chao, ...
Abstract Background: Several years after sequencing the human genome and the mouse genome, much remains to be discovered about the functions of most human and mouse genes. Computational prediction of...
Stability of Metallic Structure in Compressed Solid GeH4 (2008)
Zhang, Chao, Li, Yanling, Chen, Xiaojia, Zhang, Ruiqin, Lin, Haiqing
We study the electronic and lattice dynamical properties of compressed solid germane in the pressure range up to 200 GPa with density functional theory. A stable metallic structure, Aba2, with a...
* To whom correspondence should be addressed: (2008)
Carlos J. Camacho, Chao Zhang, Carlos J. Camacho
Summary: Interaction free energies are crucial to analyze binding propensities in proteins. Although the problem of computing binding free energies remains open, approximate estimates have become...
Two ultracold atoms in a completely anisotropic trap (2008)
As a limiting case of ultracold atoms trapped in deep optical lattices, we consider two interacting atoms trapped in a general anisotropic harmonic oscillator potential, and obtain exact solutions of...
Fingerprint Reference Point Detection Based on Local Axial Symmetry (2008)
Tong Liu, Chao Zhang, Pengwei Hao
Reference point detection is an important process for fingerprint analysis. In this paper, we propose a novel feature which is named local axial symmetry (LAS) and present an algorithm to calculate...
Shear-Resize Factorizations for Fast Image Registration * (2008)
Ying Chen, Pengwei Hao, Chao Zhang
Abstract—Owing to its effectiveness and simplicity, intensitybased method works well for registration of images. However, it needs a large amount of computation for geometric transformation. In...
Construction and Performance Analysis of OVSF-ZCZ Codes Based on LS and GO Sequences (2008)
ZHANG, Chao, TAO, Xiaoming, LU, Jianhua
Zero Correlation Zone (ZCZ) sequences have been confirmed the capability in interference mitigation in multipath fading channel. On the other hand, Orthogonal Variable Spreading Factor (OVSF) codes...
Adaptive CI-OSDM in Time-Frequency Selective Fading Channel (2008)
TAO, Xiaoming, ZHANG, Chao, LU, Jianhua, SUEHIRO, Naoki
Orthogonal Signal Division Multiplexing (OSDM), also known as SD-OFDM, has been proposed for information transmission with high spectrum efficiency. In this paper, a new signal construction method...
Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast (2008)
Wan, Lihong, Niu, Hengyao, Futcher, Bruce, Zhang, Chao, Shokat, Kevan M., Boulton, Simon J., ...
S-phase cyclin-dependent kinase Cdc28–Clb5 (CDK-S) and Dbf4-dependent kinase Cdc7–Dbf4 (DDK) are highly conserved kinases well known for their roles in the initiation of DNA replication. CDK-S is...
Doppler Diversity in MC-CDMA Systems with T-ZCZ Sequences for Doppler Spread Cancelation (2007)
TAO, Xiaoming, ZHANG, Chao, LU, Jianhua
Doppler diversity has been proven effective to combat time variation caused by Doppler spread in single carrier systems. However, it is not efficient to directly apply Doppler diversity into...
Suppression of p53-dependent senescence by the JNK signal transduction pathway (2007)
Das, Madhumita, Jiang, Feng, Sluss, Hayla Karen, Zhang, Chao, Shokat, Kevan M., Flavell, Richard A., ...
The JNK signaling pathway is implicated in the regulation of the AP1 transcription factor and cell proliferation. Here, we examine the role of JNK by using conditional and chemical genetic alleles of...
Orientation dependence of the optical spectra in graphene at high frequencies (2007)
Zhang, Chao, Chen, Lei, Ma, Zhongshui
On the basis of the Kubo formula we evaluated the optical conductivity of a graphene sheet. The full behavior of frequency as well as temperature dependence of the optical conductivity is presented....
Enhancement of polarization in a spin-orbit coupling quantum wire with a constriction (2007)
Liu, Jun-Feng, Zhong, Zhi-Cheng, Chen, Lei, Li, Dingping, Zhang, Chao, Ma, Zhongshui
We investigate the enhancement of spin polarization in a quantum wire in the presence of a constriction and a spin-orbit coupling segment. It is shown that the spin-filtering effect is significantly...
Improvement of the electromagnetic enhancement in Surface Enhanced Raman Spectroscopy (2007)
In this thesis, several ways to improve the electromagnetic (EM) enhancement in Surface Enhanced Raman Spectroscopy (SERS) are explored. Some factors influencing the EM enhancement, including...
Qin, Yi-qiang, Zhang, Chao, Zhu, Yong-yuan
The wave-front engineering for nonlinear optical interactions was discussed. Using Huygens-Fresnel principle we developed a general theory and technique for domain engineering with conventional...
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics (2007)
Blair, Jimmy A., Rauh, Daniel, Kung, Charles, Yun, Cai-Hong, Fan, Qi-Wen, Rode, Haridas, ...
Enhancement of polarization in a spin-orbit coupling quantum wire with a constriction (2007)
Liu, Jun-Feng, Zhong, Zhi-Cheng, Chen, Lei, Li, Dingping, Zhang, Chao, Ma, Zhongshui
We investigate the enhancement of spin polarization in a quantum wire in the presence of a constriction and a spin-orbit coupling segment. It is shown that the spin-filtering effect is significantly...
Radioiodine Labeled Anti-MIF McAb: A Potential Agent for Inflammation Imaging (2007)
Chao Zhang, Gui-hua Hou, Jian-kui Han, Jing Song, Ting Liang
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that may play a role in the pathogenesis of inflammation. Radiolabeled anti-MIF McAb can be used to detect in vivo...
Radioiodine Labeled Anti-MIF McAb: A Potential Agent for Inflammation Imaging (2007)
Chao Zhang, Gui-hua Hou, Jian-kui Han, Jing Song, Ting Liang
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that may play a role in the pathogenesis of inflammation. Radiolabeled anti-MIF McAb can be used to detect in vivo...
Spatial dispersion and energy in strong chiral medium (2006)
Since the discovery of backward-wave materials, people have tried to realize strong chiral medium, which is traditionally thought impossible mainly for the reason of energy and spatial dispersion. We...
ERM-SNCP Model for Traffic Equilibrium under Uncertainty(Theory of Modeling and Optimization) (2006)
Zhang, Rongfeng, Ruan, Dike, Zhang, Chao
Abstract Background The low proliferative viability of human nucleus pulposus(NP) cells is considered as a cause of intervertebral discs degeneration. Growth factors, such as TGF-β1 and IGF-1, have...
Negative reflections of electromagnetic waves in chiral media (2006)
We investigate the reflection properties of electromagnetic/optical waves in isotropic chiral media. When the chiral parameter is strong enough, we show that an unusual \emph{negative reflection}...
Wei, Feng, Wang, Guo-Du, Zhang, Chao, Shokat, Kevan M, Wang, Huimin, Tsien, Joe Z, ...
Abstract Activity-dependent synaptic plasticity is known to be important in learning and memory, persistent pain and drug addiction. Glutamate NMDA receptor activation stimulates several protein...
Robust Solution of Monotone Stochastic Linear Complementarity Problems 1 (2006)
Xiaojun Chen, Chao Zhang, Masao Fukushima
Abstract. We consider the stochastic linear complementarity problem (SLCP) involving a random matrix whose expectation matrix is positive semi-definite. We show that the expected residual...
Sequence Set with Three Zero Correlation Zones and Its Application in MC-CDMA System (2006)
ZHANG, Chao, TAO, Xiaoming, YAMADA, Shigeki, HATORI, Mitsutoshi
Sequence set with Three Zero Correlation Zones (T-ZCZ) can efficiently mitigate the Multiple Access Interference (MAI) and Inter Symbol Interference (ISI) caused by multi-path in CDMA system. In this...
The Design of a Monolithic MSTP ASIC (2006)
WANG, Peng, ZHANG, Chao, HUA, Nan, JIN, De-peng, ZENG, Lie-guang
A highly integrated monolithic Multi-Service Transport Platform (MSTP) ASIC MSEOSX8-6 incorporating more than 26M transistors has been fabricated with 0.18 μm CMOS technology. The chip is a powerful...
Sequence Set with Three Low Correlation Zones (2006)
TAO, Xiaoming, ZHANG, Chao, LU, Jianhua
Sequence set with Three Zero Correlation Zones (T-ZCZ) is applied in Quasi-Synchronized CDMA communication system to reduce the Multiple Access Interference (MAI) and Inter Symbol Interference (ISI)....
A Computational Study of Gas-solid Flow in an Enhanced Solid Entrainment (ESE) Nozzle System (2005)
Cui, Maopei, Straatman, Anthony G, Zhang, Chao
A numerical study has been undertaken to explore the influence of geometry and flow parameters on the entrainment of solid in an ESE nozzle system immersed in a fluidized riser. A fully...
A Computational Study of Gas-solid Flow in an Enhanced Solid Entrainment (ESE) Nozzle System (2005)
Cui, Maopei, Straatman, Anthony G, Zhang, Chao
A numerical study has been undertaken to explore the influence of geometry and flow parameters on the entrainment of solid in an ESE nozzle system immersed in a fluidized riser. A fully...
A Computational Study of Gas-solid Flow in an Enhanced Solid Entrainment (ESE) Nozzle System (2005)
Cui, Maopei, Straatman, Anthony G, Zhang, Chao
A numerical study has been undertaken to explore the influence of geometry and flow parameters on the entrainment of solid in an ESE nozzle system immersed in a fluidized riser. A fully...
A Computational Study of Gas-solid Flow in an Enhanced Solid Entrainment (ESE) Nozzle System (2005)
Cui, Maopei, Straatman, Anthony G, Zhang, Chao
A numerical study has been undertaken to explore the influence of geometry and flow parameters on the entrainment of solid in an ESE nozzle system immersed in a fluidized riser. A fully...
An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules (2005)
Masahiro Tanaka, Raynard Bateman, Daniel Rauh, Eugeni Vaisberg, Shyam Ramachandani, Chao Zhang, ...
An imaging-based screen, followed by structural and functional analysis, led to the discovery of new inhibitors of carbonyl reductase 1, a potential anticancer target.
An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules (2005)
Masahiro Tanaka, Raynard Bateman, Daniel Rauh, Eugeni Vaisberg, Shyam Ramachandani, Chao Zhang, ...
We have implemented an unbiased cell morphology–based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay...
FastContact: rapid estimate of contact and binding free energies (2005)
doi:10.1093/bioinformatics/bti322
Fingerprint indexing based on singular points (2005)
Tong Liu, Guocai Zhu, Chao Zhang, Pengwei Hao
Abstract—Fingerprint indexing is an efficient technique that greatly improves the performance of Automated Fingerprint Identification Systems. We propose a continuous fingerprint indexing method...
Novel Sequence Pair and Set with Three Zero Correlation Windows (2005)
ZHANG, Chao, LIN, Xiaokang, HATORI, Mitsutoshi
In this paper, we present a set of sequence pairs which produce zero correlation windows not only in the middle part of the sum of aperiodic correlation functions, but also in the two terminal parts....
FastContact: rapid estimate of contact and binding free energies (2005)
Camacho, Carlos J., Zhang, Chao
Summary: Interaction free energies are crucial for analyzing binding propensities in proteins. Although the problem of computing binding free energies remains open, approximate estimates have become...
Two Dimensional Combined Complementary Sequence and Its Application in Multi-Carrier CDMA (2005)
ZHANG, Chao, LIN, Xiaokang, HATORI, Mitsutoshi
Multi-Carrier CDMA (MC-CDMA) has been considered as a combination of the techniques of Code Division Multiple Access (CDMA) and Orthogonal Frequency Division Multiplex (OFDM). However, even until...
General Method to Construct LS Codes by Complete Complementary Sequences (2005)
ZHANG, Chao, LIN, Xiaokang, YAMADA, Shigeki, HATORI, Mitsutoshi
Large Area Synchronized (LAS)-CDMA, actually composed of LA codes and pulse compressing LS codes, has been proposed as a most promising scheme in 3G and 4G wireless communications. LS codes are...
FastContact: rapid estimate of contact and binding free energies (2005)
Camacho, Carlos J., Zhang, Chao
Summary: Interaction free energies are crucial to analyze binding propensities in proteins. Although the problem of computing binding free energies remains open, approximate estimates have become...
Detectability of Upgoing Sleptons (2004)
Some supersymmetric models predicted long lived charged sleptons. Following Albuquerque, Burdman and Chacko \cite{albu}, we consider an exact process where the $ \widetilde{\tau}$, the supersymmetry...
A Parametric Study of the Oxygen Elimination Process in a Packed Bed (2004)
Natarajan, Shankar, Zhang, Chao, Briens, Cedric
This study is concerned with an industrial application involved in the manufacture of the polymer Nylon12, which is polymerised from solid monomer particles. There exists interstitial air among those...
A Parametric Study of the Oxygen Elimination Process in a Packed Bed (2004)
Natarajan, Shankar, Zhang, Chao, Briens, Cedric
This study is concerned with an industrial application involved in the manufacture of the polymer Nylon12, which is polymerised from solid monomer particles. There exists interstitial air among those...
A Parametric Study of the Oxygen Elimination Process in a Packed Bed (2004)
Natarajan, Shankar, Zhang, Chao, Briens, Cedric
This study is concerned with an industrial application involved in the manufacture of the polymer Nylon12, which is polymerised from solid monomer particles. There exists interstitial air among those...
A Parametric Study of the Oxygen Elimination Process in a Packed Bed (2004)
Natarajan, Shankar, Zhang, Chao, Briens, Cedric
This study is concerned with an industrial application involved in the manufacture of the polymer Nylon12, which is polymerised from solid monomer particles. There exists interstitial air among those...
Phenomenology of quintessino dark matter -- Production of NLSP particles (2004)
Bi, Xiao-Jun, Wang, Jian-Xiong, Zhang, Chao, Zhang, Xinmin
In the model of quintessino as dark matter particle, the dark matter and dark energy are unified in one superfield, where the dynamics of the Quintessence drives the Universe acceleration and its...
Consumer willingness to pay for non-genetically modified and organic foods / (2003)
Thesis (M.S.)--University of Delaware, 2004.
Unfolded Proteins in the Endoplasmic Reticulum Cause (2003)
Feroz R. Papa, Chao Zhang, Kevan Shokat, Peter Walter
ough the ER stress sensor Ire1, a single-spanning ER transmembrane protein with three functional domains (4). The most amino-terminal domain, which resides in the ER lumen, senses elevated levels of...
A global representation of the protein fold space (2003)
Jingtong Hou, Gregory Sims, Chao Zhang, Sung-hou Kim
One of the principal goals of the structural genomics initiative is to identify the total repertoire of protein folds and to obtain a global view of the “protein structure universe”. Here, we...
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2 (2003)
Benjamin, Kirsten R., Zhang, Chao, Shokat, Kevan M., Herskowitz, Ira
Meiosis is thought to require the protein kinase Ime2 early for DNA replication and the cyclin-dependent kinase Cdc28 late for chromosome segregation. To elucidate the roles of these kinases, we...
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2 (2003)
Benjamin, Kirsten R., Zhang, Chao, Shokat, Kevan M., Herskowitz, Ira
Meiosis is thought to require the protein kinase Ime2 early for DNA replication and the cyclin-dependent kinase Cdc28 late for chromosome segregation. To elucidate the roles of these kinases, we...
Space charge and conduction in LDPE-polypropylene copolymer blends (2001)
Zhang, Chao, Mizutani, Teruyoshi, Kaneko, Kazue, Mori, Tatsuo, Ishioka, Mitsugu
In the previous paper, the electrical breakdown properties of blend polymers of LDPE and polypropylene copolymer were investigated. The impulse breakdown strength in the high temperature region...
Design and study of the anisotropic stack/heat-exchanger refrigerator / (2001)
Thesis (Ph.D.)--Pennsylvania State University, 2001.
A numerical study of the fluid physics occurring in glottal geometries /--by Chao Zhang. (2000)
Typescript.
Nonlinear Distortion Correction in Endoscopic Video Images," presented at (2000)
Chao Zhang, James P. Helferty, Geoffrey Mclennan, William E. Higgins
Modern video-based endoscopes offer physicians a wide-angle field of view for minimally-invasive procedures. Unfortunately, inherent barrel distortion prevents accurate perception of range. This...
Vita.
and peptide recognition (1996)
Email Alerting, Chao Zhang, James L. Coriwti'e, Charles Delisi
Consistency in structural energetics of protein folding and peptide recognition
Chao Zhang, Baozong Yuan, Northern Jiaotong
We propose a new kind of models, which are called Nonlinear Deformable Superquadric (NDS) models, for representing and reconstructing 3D objects. Instead of linear tapering deformation, a piecewise...
Numerical predictions of shell-side fluid flow and heat transfer in heat exchangers. (1989)
Thesis (Ph. D.)--University of New Brunswick, 1989.
Environment-dependent residue contact energies for proteins
We examine the interactions between amino acid residues in the context of their secondary structural environments (helix, strand, and coil) in proteins. Effective contact energies for an expanded...
Fold prediction of helical proteins using torsion angle dynamics and predicted restraints
Zhang, Chao, Hou, Jingtong, Kim, Sung-Hou
We describe a procedure for predicting the tertiary folds of α-helical proteins from their primary sequences. The central component of the procedure is a method for predicting interhelical contacts...
Chemical Genetic Analysis of Apg1 Reveals A Non-kinase Role in the Induction of Autophagy
Abeliovich, Hagai, Zhang, Chao, Dunn, William A., Shokat, Kevan M., Klionsky, Daniel J.
Macroautophagy is a catabolic membrane trafficking phenomenon that is observed in all eukaryotic cells in response to various stimuli, such as nitrogen starvation and challenge with specific...
A global representation of the protein fold space
Hou, Jingtong, Sims, Gregory E., Zhang, Chao, Kim, Sung-Hou
One of the principal goals of the structural genomics initiative is to identify the total repertoire of protein folds and obtain a global view of the “protein structure universe.” Here, we...
Wang, Huimin, Shimizu, Eiji, Tang, Ya-Ping, Cho, Min, Kyin, Maureen, Zuo, Wenqi, ...
By integrating convergent protein engineering and rational inhibitor design, we have developed an in vivo conditional protein knockout and/or manipulation technology. This method is based on the...
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2
Benjamin, Kirsten R., Zhang, Chao, Shokat, Kevan M., Herskowitz, Ira
Meiosis is thought to require the protein kinase Ime2 early for DNA replication and the cyclin-dependent kinase Cdc28 late for chromosome segregation. To elucidate the roles of these kinases, we...
Wan, Lihong, De Los Santos, Teresa, Zhang, Chao, Shokat, Kevan, Hollingsworth, Nancy M.
Three meiosis-specific chromosomal components in budding yeast, Mek1, Red1, and Hop1, are required for recombination, proper segregation of homologs, and the meiotic recombination checkpoint. Mek1 is...
An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules
Tanaka, Masahiro, Bateman, Raynard, Rauh, Daniel, Vaisberg, Eugeni, Ramachandani, Shyam, Zhang, Chao, ...
We have implemented an unbiased cell morphology–based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay...
The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Wang, Weiru, Zhang, Chao, Marimuthu, Adhirai, Krupka, Heike I., Tabrizizad, Maryam, Shelloe, Rafe, ...
Steroidogenic factor-1 (SF-1) and liver receptor homologue-1 (LRH-1) belong to the fushi tarazu factor 1 subfamily of nuclear receptors. SF-1 is an essential factor for sex determination during...
Wei, Feng, Wang, Guo-Du, Zhang, Chao, Shokat, Kevan M, Wang, Huimin, Tsien, Joe Z, ...
Activity-dependent synaptic plasticity is known to be important in learning and memory, persistent pain and drug addiction. Glutamate NMDA receptor activation stimulates several protein kinases,...
Wang, Weiru, Marimuthu, Adhirai, Tsai, James, Kumar, Abhinav, Krupka, Heike I., Zhang, Chao, ...
Protein kinases are a large family of cell signaling mediators undergoing intensive research to identify inhibitors or modulators useful for medicine. As one strategy, small-molecule compounds that...
Environment-dependent residue contact energies for proteins
We examine the interactions between amino acid residues in the context of their secondary structural environments (helix, strand, and coil) in proteins. Effective contact energies for an expanded...
Fold prediction of helical proteins using torsion angle dynamics and predicted restraints
Zhang, Chao, Hou, Jingtong, Kim, Sung-Hou
We describe a procedure for predicting the tertiary folds of α-helical proteins from their primary sequences. The central component of the procedure is a method for predicting interhelical contacts...
Chemical Genetic Analysis of Apg1 Reveals A Non-kinase Role in the Induction of Autophagy
Abeliovich, Hagai, Zhang, Chao, Dunn, William A., Shokat, Kevan M., Klionsky, Daniel J.
Macroautophagy is a catabolic membrane trafficking phenomenon that is observed in all eukaryotic cells in response to various stimuli, such as nitrogen starvation and challenge with specific...
A global representation of the protein fold space
Hou, Jingtong, Sims, Gregory E., Zhang, Chao, Kim, Sung-Hou
One of the principal goals of the structural genomics initiative is to identify the total repertoire of protein folds and obtain a global view of the “protein structure universe.” Here, we...
Wang, Huimin, Shimizu, Eiji, Tang, Ya-Ping, Cho, Min, Kyin, Maureen, Zuo, Wenqi, ...
By integrating convergent protein engineering and rational inhibitor design, we have developed an in vivo conditional protein knockout and/or manipulation technology. This method is based on the...
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2
Benjamin, Kirsten R., Zhang, Chao, Shokat, Kevan M., Herskowitz, Ira
Meiosis is thought to require the protein kinase Ime2 early for DNA replication and the cyclin-dependent kinase Cdc28 late for chromosome segregation. To elucidate the roles of these kinases, we...
Wan, Lihong, De Los Santos, Teresa, Zhang, Chao, Shokat, Kevan, Hollingsworth, Nancy M.
Three meiosis-specific chromosomal components in budding yeast, Mek1, Red1, and Hop1, are required for recombination, proper segregation of homologs, and the meiotic recombination checkpoint. Mek1 is...
Hou, Jingtong, Jun, Se-Ran, Zhang, Chao, Kim, Sung-Hou
We have constructed a map of the “protein structure space” by using the pairwise structural similarity scores calculated for all nonredundant protein structures determined experimentally. As...
An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules
Tanaka, Masahiro, Bateman, Raynard, Rauh, Daniel, Vaisberg, Eugeni, Ramachandani, Shyam, Zhang, Chao, ...
We have implemented an unbiased cell morphology–based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay...
The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Wang, Weiru, Zhang, Chao, Marimuthu, Adhirai, Krupka, Heike I., Tabrizizad, Maryam, Shelloe, Rafe, ...
Steroidogenic factor-1 (SF-1) and liver receptor homologue-1 (LRH-1) belong to the fushi tarazu factor 1 subfamily of nuclear receptors. SF-1 is an essential factor for sex determination during...
Wang, Weiru, Marimuthu, Adhirai, Tsai, James, Kumar, Abhinav, Krupka, Heike I., Zhang, Chao, ...
Protein kinases are a large family of cell signaling mediators undergoing intensive research to identify inhibitors or modulators useful for medicine. As one strategy, small-molecule compounds that...
Wei, Feng, Wang, Guo-Du, Zhang, Chao, Shokat, Kevan M, Wang, Huimin, Tsien, Joe Z, ...
Activity-dependent synaptic plasticity is known to be important in learning and memory, persistent pain and drug addiction. Glutamate NMDA receptor activation stimulates several protein kinases,...
Wan, Lihong, Zhang, Chao, Shokat, Kevan M., Hollingsworth, Nancy M.
Genetic studies in budding yeast have provided many fundamental insights into the specialized cell division of meiosis, including the identification of evolutionarily conserved meiosis-specific genes...
Burkard, Mark E., Randall, Catherine L., Larochelle, Stéphane, Zhang, Chao, Shokat, Kevan M., Fisher, Robert P., ...
Polo-like kinases (Plks) play crucial roles in mitosis and cell division. Whereas lower eukaryotes typically contain a single Plk, mammalian cells express several closely related but functionally...
Zhang, Chao, Yang, Fan, Zhang, Xiong-Wen, Wang, Shun-Chun, Li, Mei-Hong, Lin, Li-Ping, ...
The antiangiogenic and antitumor properties of Grateloupia longifolia polysaccharide (GLP), a new type of polysaccharide isolated from the marine alga, were investigated with several in vitro and in...
Radioiodine Labeled Anti-MIF McAb: A Potential Agent for Inflammation Imaging
Zhang, Chao, Hou, Gui-hua, Han, Jian-kui, Song, Jing, Liang, Ting
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that may play a role in the pathogenesis of inflammation. Radiolabeled anti-MIF McAb can be used to detect in vivo...
Suppression of p53-dependent senescence by the JNK signal transduction pathway
Das, Madhumita, Jiang, Feng, Sluss, Hayla K., Zhang, Chao, Shokat, Kevan M., Flavell, Richard A., ...
The JNK signaling pathway is implicated in the regulation of the AP1 transcription factor and cell proliferation. Here, we examine the role of JNK by using conditional and chemical genetic alleles of...
GM Foods When an Organic Option Is Present
John C. Bernard, Chao Zhang, Katie Gifford
This research compared bids that consumers placed on non genetically modified (GM), organic, and conventional versions of food products in order to determine if the organic market well serves those...
Sekiya-Kawasaki, Mariko, Groen, Aaron Chris, Kaksonen, Marko, Watson, Hadiya A., Zhang, Chao, ...
We used chemical genetics to control the activity of budding yeast Prk1p, which is a protein kinase that is related to mammalian GAK and AAK1, and which targets several actin regulatory proteins...
Weiss, Eric L., Kurischko, Cornelia, Zhang, Chao, Shokat, Kevan, Drubin, David G., Luca, Francis C.
The Saccharomyces cerevisiae mitotic exit network (MEN) is a conserved signaling network that coordinates events associated with the M to G1 transition. We investigated the function of two S....
Advanced primary peritoneal carcinoma: clinicopathological and prognostic factor analyses
Zhang, Chao, Li, Xiao-ping, Cui, Heng, Shen, Dan-hua, Wei, Li-hui
Objective: To investigate the factors favoring a positive prognosis for advanced primary peritoneal carcinoma (PPC). Methods: Twenty-four cases meeting the criteria for PPC were analyzed...
A critical assessment of Mus musculus gene function prediction using integrated genomic evidence
Peña-Castillo, Lourdes, Tasan, Murat, Myers, Chad L, Lee, Hyunju, Joshi, Trupti, Zhang, Chao, ...
Cdc28–Clb5 (CDK-S) and Cdc7–Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast
Wan, Lihong, Niu, Hengyao, Futcher, Bruce, Zhang, Chao, Shokat, Kevan M., Boulton, Simon J., ...
S-phase cyclin-dependent kinase Cdc28–Clb5 (CDK-S) and Dbf4-dependent kinase Cdc7–Dbf4 (DDK) are highly conserved kinases well known for their roles in the initiation of DNA replication. CDK-S is...
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Tsai, James, Lee, John T., Wang, Weiru, Zhang, Jiazhong, Cho, Hanna, Mamo, Shumeye, ...
BRAFV600E is the most frequent oncogenic protein kinase mutation known. Furthermore, inhibitors targeting “active” protein kinases have demonstrated significant utility in the therapeutic...
Levin, Susan E., Zhang, Chao, Kadlecek, Theresa A., Shokat, Kevan M., Weiss, Arthur
ZAP-70 is a cytoplasmic protein tyrosine kinase that is required for T cell antigen receptor (TCR) signaling. Both mice and humans deficient in ZAP-70 fail to develop functional T cells, thus...
The Yeast LATS/Ndr Kinase Cbk1 Regulates Growth via Golgi-dependent Glycosylation and Secretion
Kurischko, Cornelia, Kuravi, Venkata K., Wannissorn, Nattha, Nazarov, Pavel A., Husain, Michelle, Zhang, Chao, ...
Saccharomyces cerevisiae Cbk1 is a LATS/Ndr protein kinase and a downstream component of the regulation of Ace2 and morphogenesis (RAM) signaling network. Cbk1 and the RAM network are required for...
Bernard, John C., Zhang, Chao, Gifford, Katie
This research compared bids that consumers placed on non genetically modified (GM), organic, and conventional versions of food products in order to determine if the organic market well serves those...
Global error bounds for the extended vertical LCP
Chao Zhang, Xiaojun Chen, Naihua Xiu
Global error bound, Row $\mathcal{W}$ -property, Extended vertical LCP,
Burkard, Mark E., Maciejowski, John, Rodriguez-Bravo, Verónica, Repka, Michael, Lowery, Drew M., Clauser, Karl R., ...
Self-regulated movement of Polo-like kinase 1 to the midzone of the mitotic spindle initiates a local signaling cascade that activates the cell division machinery at the cell's equator.
Morgan, Daniel J., Weisenhaus, Michael, Shum, Sara, Su, Thomas, Zheng, Ruimao, Zhang, Chao, ...
Studies on cAMP signaling and protein kinase A (PKA) function in vivo are limited by the lack of highly specific inhibitors that can be used in primary cell culture and whole animals. Previously we...
Hao, Ying-Xue, Zhong, Hua, Zhang, Chao, Zeng, Dong-Zu, Shi, Yan, Tang, Bo, ...
AIM: To investigate the effects of carbon dioxide (CO2) and helium insufflation administered at different pressures on the growth and apoptosis of cultured human gastric cancer cells.
Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent
Artis, Dean R., Lin, Jack J., Zhang, Chao, Wang, Weiru, Mehra, Upasana, Perreault, Mylene, ...
In a search for more effective anti-diabetic treatment, we used a process coupling low-affinity biochemical screening with high-throughput co-crystallography in the design of a series of compounds...
Zhang, Linhua, Li, Yue, Zhang, Chao, Wang, Yusheng, Song, Cunxian
The aim of the study was to investigate the tolerance and pharmacokinetics of dexamethasone (DEX)-loaded poly(lactic acid–co-glycolic acid) nanoparticles (DEX-NPs) in rabbits after intravitreal...
Ning, Feng Tao, Zhang, Chao, Fujita, Rod
Many authors have suggested the use of a cap and trade auction system to help reduce bycatch--the incidental take of species by fishing gear targeting other species--of sea turtles in the...