The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo (2007)
Monet, Marie, Domenga, Valérie, Lemaire, Barbara, Souilhol, Céline, Langa, Francina, Babinet, Charles, ...
Cerebral Autosomal Dominant Arteriopathy with Subcortical infarcts and Leukoencephalopathy (CADASIL) is the most prominent known cause of inherited stroke and vascular dementia in human adult. The...
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo. (2006)
Souilhol, Céline, Cormier, Sarah, Monet, Marie, Vandormael-Pournin, Sandrine, Joutel, Anne, Babinet, Charles, ...
The Notch signaling pathway plays multiple and important roles in mammals. However, several aspects of its action, in particular, the precise mapping of its sites of activity, remain unclear. To...
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo. (2006)
Souilhol, Céline, Cormier, Sarah, Monet, Marie, Vandormael-Pournin, Sandrine, Joutel, Anne, Babinet, Charles, ...
The Notch signaling pathway plays multiple and important roles in mammals. However, several aspects of its action, in particular, the precise mapping of its sites of activity, remain unclear. To...
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo. (2006)
Souilhol, Céline, Cormier, Sarah, Monet, Marie, Vandormael-Pournin, Sandrine, Joutel, Anne, Babinet, Charles, ...
The Notch signaling pathway plays multiple and important roles in mammals. However, several aspects of its action, in particular, the precise mapping of its sites of activity, remain unclear. To...
Charles Babinet, Michel Cohen-Tannoudji
Erratum to Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology...
Charles Babinet, Michel Cohen-Tannoudji
Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology
Keratin 17 null mice exhibit age- and strain-dependent alopecia (2002)
McGowan, Kevin M., Tong, Xuemei, Colucci-Guyon, Emma, Langa, Francina, Babinet, Charles, Coulombe, Pierre A.
BABINET,CHARLES, COHEN-TANNOUDJI,MICHEL
The ability to introduce genetic modifications in the germ line of complex organisms has been a long-standing goal of those who study developmental biology. In this regard, the mouse, a favorite...
Sanchez, Pierre, Drapier, Anne-Marie, Cohen-Tannoudji, Michel, Colucci, Emma, Babinet, Charles, Cazenave, Plerre-André
The establishment of the B cell repertoire depends on two major parameters. The first is determined by mechanistic processes that give rise to a great diversity of B cell receptors from a combination...
Contribution à l'étude de la RNA-polymerase de E. Coli / (1970)
Thesis (doctoral)--Université de Paris, 1970.
I-SceI-Induced Gene Replacement at a Natural Locus in Embryonic Stem Cells
Cohen-Tannoudji, Michel, Robine, Sylvie, Choulika, André, Pinto, Daniel, El Marjou, Fatima, Babinet, Charles, ...
Gene targeting is a very powerful tool for studying mammalian development and physiology and for creating models of human diseases. In many instances, however, it is desirable to study different...
Keratin 17 null mice exhibit age- and strain-dependent alopecia
McGowan, Kevin M., Tong, Xuemei, Colucci-Guyon, Emma, Langa, Francina, Babinet, Charles, Coulombe, Pierre A.
Onset of type I keratin 17 (K17) synthesis marks the adoption of an appendageal fate within embryonic ectoderm, and its expression persists in specific cell types within mature hair, glands, and...
Surface Antigens Common to Mouse Cleavage Embryos and Primitive Teratocarcinoma Cells in Culture
Artzt, Karen, Dubois, Philippe, Bennett, Dorothea, Condamine, Hubert, Babinet, Charles, Jacob, François
Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the primitive cells of teratocarcinoma. These sera react specifically with the primitive cells and are negative on...
Coumailleau, Franck, Das, Vincent, Alcover, Andres, Raposo, Graça, Vandormael-Pournin, Sandrine, Le Bras, Stéphanie, ...
Endocytosed membrane components are recycled to the cell surface either directly from early/sorting endosomes or after going through the endocytic recycling compartment (ERC). Studying recycling...
Klochendler-Yeivin, Agnes, Fiette, Laurence, Barra, Jaqueline, Muchardt, Christian, Babinet, Charles, Yaniv, Moshe
The assembly of eukaryotic DNA into nucleosomes and derived higher order structures constitutes a barrier for transcription, replication and repair. A number of chromatin remodeling complexes, as...
Artus, Jérôme, Vandormael-Pournin, Sandrine, Frödin, Morten, Nacerddine, Karim, Babinet, Charles, Cohen-Tannoudji, Michel
While highly conserved through evolution, the cell cycle has been extensively modified to adapt to new developmental programs. Recently, analyses of mouse mutants revealed that several important cell...
Cormier, Sarah, Le Bras, Stéphanie, Souilhol, Céline, Vandormael-Pournin, Sandrine, Durand, Béatrice, Babinet, Charles, ...
Notch signaling is an evolutionarily conserved pathway involved in intercellular communication and is essential for proper cell fate choices. Numerous genes participate in the modulation of the Notch...
RBP-Jκ-Dependent Notch Signaling Is Dispensable for Mouse Early Embryonic Development
Souilhol, Céline, Cormier, Sarah, Tanigaki, Kenji, Babinet, Charles, Cohen-Tannoudji, Michel
The Notch signaling pathway is an evolutionarily conserved signaling system which has been shown to be essential in cell fate specification and in numerous aspects of embryonic development in all...
I-SceI-Induced Gene Replacement at a Natural Locus in Embryonic Stem Cells
Cohen-Tannoudji, Michel, Robine, Sylvie, Choulika, André, Pinto, Daniel, El Marjou, Fatima, Babinet, Charles, ...
Gene targeting is a very powerful tool for studying mammalian development and physiology and for creating models of human diseases. In many instances, however, it is desirable to study different...
Keratin 17 null mice exhibit age- and strain-dependent alopecia
McGowan, Kevin M., Tong, Xuemei, Colucci-Guyon, Emma, Langa, Francina, Babinet, Charles, Coulombe, Pierre A.
Onset of type I keratin 17 (K17) synthesis marks the adoption of an appendageal fate within embryonic ectoderm, and its expression persists in specific cell types within mature hair, glands, and...
Surface Antigens Common to Mouse Cleavage Embryos and Primitive Teratocarcinoma Cells in Culture
Artzt, Karen, Dubois, Philippe, Bennett, Dorothea, Condamine, Hubert, Babinet, Charles, Jacob, François
Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the primitive cells of teratocarcinoma. These sera react specifically with the primitive cells and are negative on...
Coumailleau, Franck, Das, Vincent, Alcover, Andres, Raposo, Graça, Vandormael-Pournin, Sandrine, Le Bras, Stéphanie, ...
Endocytosed membrane components are recycled to the cell surface either directly from early/sorting endosomes or after going through the endocytic recycling compartment (ERC). Studying recycling...
Klochendler-Yeivin, Agnes, Fiette, Laurence, Barra, Jaqueline, Muchardt, Christian, Babinet, Charles, Yaniv, Moshe
The assembly of eukaryotic DNA into nucleosomes and derived higher order structures constitutes a barrier for transcription, replication and repair. A number of chromatin remodeling complexes, as...
Artus, Jérôme, Vandormael-Pournin, Sandrine, Frödin, Morten, Nacerddine, Karim, Babinet, Charles, Cohen-Tannoudji, Michel
While highly conserved through evolution, the cell cycle has been extensively modified to adapt to new developmental programs. Recently, analyses of mouse mutants revealed that several important cell...
Cormier, Sarah, Le Bras, Stéphanie, Souilhol, Céline, Vandormael-Pournin, Sandrine, Durand, Béatrice, Babinet, Charles, ...
Notch signaling is an evolutionarily conserved pathway involved in intercellular communication and is essential for proper cell fate choices. Numerous genes participate in the modulation of the Notch...
RBP-Jκ-Dependent Notch Signaling Is Dispensable for Mouse Early Embryonic Development
Souilhol, Céline, Cormier, Sarah, Tanigaki, Kenji, Babinet, Charles, Cohen-Tannoudji, Michel
The Notch signaling pathway is an evolutionarily conserved signaling system which has been shown to be essential in cell fate specification and in numerous aspects of embryonic development in all...
Inactivation of CUG-BP1/CELF1 Causes Growth, Viability, and Spermatogenesis Defects in Mice▿
Kress, Chantal, Gautier-Courteille, Carole, Osborne, H. Beverley, Babinet, Charles, Paillard, Luc
CUG-BP1/CELF1 is a multifunctional RNA-binding protein involved in the regulation of alternative splicing and translation. To elucidate its role in mammalian development, we produced mice in which...
Li, Zhenlin, Mericskay, Mathias, Agbulut, Onnik, Butler-Browne, Gillian, Carlsson, Lena, Thornell, Lars-Eric, ...
A null mutation was introduced into the mouse desmin gene by homologous recombination. The desmin knockout mice (Des −/−) develop normally and are fertile. However, defects were observed after...
In Vivo, Villin Is Required for Ca2+-Dependent F-Actin Disruption in Intestinal Brush Borders
Ferrary, Evelyne, Cohen-Tannoudji, Michel, Pehau-Arnaudet, Gérard, Lapillonne, Alexandre, Athman, Rafika, Ruiz, Tereza, ...
Villin is an actin-binding protein localized in intestinal and kidney brush borders. In vitro, villin has been demonstrated to bundle and sever F-actin in a Ca2+-dependent manner. We generated...
Wong, Pauline, Colucci-Guyon, Emma, Takahashi, Kenzo, Gu, Changhong, Babinet, Charles, Coulombe, Pierre A.
Mammalian genomes feature multiple genes encoding highly related keratin 6 (K6) isoforms. These type II keratins show a complex regulation with constitutive and inducible components in several...