Chella David

Mapping myasthenia gravis–associated T cell epitopes on human acetylcholine receptors in HLA transgenic mice

Yang, Huan, Goluszko, Elzbieta, David, Chella, Okita, David K., Conti-Fine, Bianca, Chan, Teh-sheng, ...

Susceptibility to myasthenia gravis (MG) is positively linked to expression of HLA-DQ8 and DR3 molecules and negatively linked to expression of the DQ6 molecule. To elucidate the molecular basis of...

A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice

Marietta, Eric, Black, Kay, Camilleri, Michael, Krause, Patricia, Rogers, Roy S., David, Chella, ...

Dermatitis herpetiformis (DH) is an autoimmune blistering skin disorder that is associated with gluten sensitivity. It presents as a papulovesicular rash and is often associated with enteropathy. The...

Mapping myasthenia gravis–associated T cell epitopes on human acetylcholine receptors in HLA transgenic mice

Yang, Huan, Goluszko, Elzbieta, David, Chella, Okita, David K., Conti-Fine, Bianca, Chan, Teh-sheng, ...

Susceptibility to myasthenia gravis (MG) is positively linked to expression of HLA-DQ8 and DR3 molecules and negatively linked to expression of the DQ6 molecule. To elucidate the molecular basis of...

A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice

Marietta, Eric, Black, Kay, Camilleri, Michael, Krause, Patricia, Rogers, Roy S., David, Chella, ...

Dermatitis herpetiformis (DH) is an autoimmune blistering skin disorder that is associated with gluten sensitivity. It presents as a papulovesicular rash and is often associated with enteropathy. The...

In Vivo Evidence for the Contribution of Human Histocompatibility Leukocyte Antigen (Hla)-Dq Molecules to the Development of Diabetes

Wen, Li, Wong, F. Susan, Tang, Jie, Chen, Ning-Yuan, Altieri, Martha, David, Chella, ...

Although DQA1*0301/DQB1*0302 is the human histocompatibility leukocyte antigen (HLA) class II gene most commonly associated with human type 1 diabetes, direct in vivo experimental evidence for its...

Human HLA-DR Transgenes Protect Mice from Fatal Virus-Induced Encephalomyelitis and Chronic Demyelination▿

Rodriguez, Moses, Zoecklein, Laurie, Kerkvliet, Jason G., Pavelko, Kevin D., Papke, Louisa, Howe, Charles L., ...

We evaluated the participatory role of human HLA-DR molecules in control of virus from the central nervous system and in the development of subsequent spinal cord demyelination. The experiments...