Klingelhoefer, Jochen W., Moutsianas, Loukas, Holmes, Chris
Motivation: Short interfering RNA (siRNA)-induced RNA interference is an endogenous pathway in sequence-specific gene silencing. The potency of different siRNAs to inhibit a common target varies...
Papaspiliopoulos, Omiros, Yau, Chris, Roberts, Gareth, Holmes, Chris
We consider the development of Bayesian Nonparametric methods for product partition models such as Hidden Markov Models and change point models. Our approach uses a Mixture of Dirichlet Process (MDP)...
Issue 1.0 A Review of Frame Technology (2007)
Frame Technology was introduced during the early 1980’s as an approach to providing significant levels of improvement in software productivity through adaptive reuse. However, despite the claims of...
Direct UV written optical planar devices (2006)
Adikan, Rafiq, Holmes, Chris, Major, Huw, Gawith, Corin, Gates, James, Smith, Peter
The importance of optical technology is reflected by it being one of Malaysia's Ministry of Science, Technology and Innovation Strategic Research Areas. Analogous to the silicon chip, the impetus now...
All systems GO for understanding mouse gene function (2004)
Holmes, Chris, Brown, Steve DM
Abstract It is widely supposed that the tissue specificity of gene expression indicates gene function. Now, an extensive analysis of gene expression in the mouse reveals that quantitative measurement...
All systems GO for understanding mouse gene function (2004)
Holmes, Chris, Brown, Steve D M
It is widely supposed that the tissue specificity of gene expression indicates gene function. Now, an extensive analysis of gene expression in the mouse reveals that quantitative measurement of...
Bayesian Wavelet Analysis with a Model Complexity Prior (1998)
this paper Bayesian methods for the selection and shrinkage of wavelet coefficients are considered. The wavelet coefficients are assigned a zero mean normal prior with precision matrix
Typescript (photocopy).
All systems GO for understanding mouse gene function
Holmes, Chris, Brown, Steve DM
It is widely supposed that the tissue specificity of gene expression indicates gene function. Now, an extensive analysis of gene expression in the mouse reveals that quantitative measurement of...
All systems GO for understanding mouse gene function
Holmes, Chris, Brown, Steve DM
It is widely supposed that the tissue specificity of gene expression indicates gene function. Now, an extensive analysis of gene expression in the mouse reveals that quantitative measurement of...
Flexible Threshold Models for Modelling Interest Rate Volatility
Petros Dellaportas, Chris Holmes
This paper focuses on interest rate models with regime switching and extends previous nonlinear threshold models by relaxing the assumption of a fixed number of regimes. Instead we suggest automatic...