Christian Brun-Buisson

Risk stratification of early admission to the intensive care unit of patients with no major criteria of severe community-acquired pneumonia: development of an international prediction rule (2009)

Renaud, Bertrand, Labarère, José, Coma, Eva, Santin, Aline, Hayon, Jan, Gurgui, Mercé, ...

Abstract Introduction To identify risk factors for early (< three days) intensive care unit (ICU) admission of patients hospitalised with community-acquired pneumonia (CAP) and not requiring...

Impact of a computer-generated alert system prompting review of antibiotic use in hospitals (2009)

Lesprit, Philippe, Duong, Trung, Girou, Emmanuelle, Hemery, François, Brun-Buisson, Christian

Objectives The aim of this study was to measure the impact on antibiotic use of a computer-generated alert prompting post-prescription review and direct counselling in hospital wards. Methods A...

Brachyspira pilosicolibloodstream infections: Case report and review of the literature (2008)

Bait-Merabet, Lilia, Thille, Arnaud, Legrand, Patrick, Brun-Buisson, Christian, Cattoir, Vincent

Abstract Brachyspira pilosicoli is the etiologic agent of human and animal intestinal spirochetosis and is rarely implicated as a cause of bacteremia. Here, we describe the case of a B. pilosicoli...

Inappropriate prescribing of aminoglycosides: risk factors and impact of an antibiotic control team (2006)

Zahar, Jean-Ralph, Rioux, Christophe, Girou, Emmanuelle, Hulin, Anne, Sauve, Colette, Bernier-Combes, Alexandra, ...

Objectives: Many factors are involved in the appropriate use of aminoglycosides, such as modalities of administration, drug levels monitoring and duration of treatment. We assessed prospectively the...

Inappropriate prescribing of aminoglycosides: risk factors and impact of an antibiotic control team (2006)

Zahar, Jean-Ralph, Rioux, Christophe, Girou, Emmanuelle, Hulin, Anne, Sauve, Colette, Bernier-Combes, Alexandra, ...

Objectives: Many factors are involved in the appropriate use of aminoglycosides, such as modalities of administration, drug levels monitoring and duration of treatment. We assessed prospectively the...

Ethics roundtable debate: A patient dies from an ICU-acquired infection related to methicillin-resistant Staphylococcus aureus– how do you defend your case and your team? (2004)

Vincent, Jean-Louis, Brun-Buisson, Christian, Niederman, Michael, Haenni, Christian, Harbarth, Stephan, Sprumont, Dominique, ...

Abstract An elderly patient dies from septic shock in the intensive care unit. This is perhaps not an unusual scenario, but in this case the sepsis happens to have been due to methicillin-resistant...

Appropriate use of restricted antimicrobial agents in hospitals: the importance of empirical therapy and assisted re-evaluation (2000)

Thuong, Marie, Shortgen, Frédérique, Zazempa, Virginie, Girou, Emmanuelle, Soussy, Claude J., Brun-Buisson, Christian

We evaluated the appropriateness of use of restricted antimicrobial agents in the context of a newly implemented order form and delivery system for restricted antimicrobial agents, using sequential...

Use of the coagulase gene typing method for detection of carriers of methicillin-resistant Staphylococcus aureus (1996)

Lawrence, Christine, Cosseron, Marie, Mimoz, Olivier, Brun-Buisson, Christian, Costa, Yannick, Samii, Kamran, ...

Strains of Staphylococcus aureus can be typed on the basis of the polymorphism of the coagulase gene. DNA fragments generated after amplification by polymerase chain reaction (PCR) of the variable...

Usefulness of Routine Epicardial Pacing Wire Culture for Early Prediction of Poststernotomy Mediastinitis

Mekontso-Dessap, Armand, Honoré, Stéphanie, Kirsch, Matthias, Houël, Rémi, Loisance, Daniel, Brun-Buisson, Christian

Poststernotomy mediastinitis (PSM) is one of the most serious complications of cardiac surgery, and its associated morbidity and mortality demand early recognition for emergency therapy. In this...

Ethics roundtable debate: A patient dies from an ICU-acquired infection related to methicillin-resistant Staphylococcus aureus – how do you defend your case and your team?

Vincent, Jean-Louis, Brun-Buisson, Christian, Niederman, Michael, Haenni, Christian, Harbarth, Stephan, Sprumont, Dominique, ...

An elderly patient dies from septic shock in the intensive care unit. This is perhaps not an unusual scenario, but in this case the sepsis happens to have been due to methicillin-resistant...

Usefulness of Routine Epicardial Pacing Wire Culture for Early Prediction of Poststernotomy Mediastinitis

Mekontso-Dessap, Armand, Honoré, Stéphanie, Kirsch, Matthias, Houël, Rémi, Loisance, Daniel, Brun-Buisson, Christian

Poststernotomy mediastinitis (PSM) is one of the most serious complications of cardiac surgery, and its associated morbidity and mortality demand early recognition for emergency therapy. In this...

Ethics roundtable debate: A patient dies from an ICU-acquired infection related to methicillin-resistant Staphylococcus aureus – how do you defend your case and your team?

Vincent, Jean-Louis, Brun-Buisson, Christian, Niederman, Michael, Haenni, Christian, Harbarth, Stephan, Sprumont, Dominique, ...

An elderly patient dies from septic shock in the intensive care unit. This is perhaps not an unusual scenario, but in this case the sepsis happens to have been due to methicillin-resistant...

Preventing ventilator associated pneumonia

Brun-Buisson, Christian

Oral antiseptic agents should be part of a multifaceted preventive care package

A Model to Compute the Medical Cost of Patients in Intensive Care

Carine Chaix, Isabelle Durand-Zaleski, Corinne Alberti, Christian Brun-Buisson

Objective: Our objective was to identify, among the information routinely collected on patients in intensive care units (ICUs), data that determine the total cost for a given patient. Design: We...

Brachyspira pilosicoli bloodstream infections: Case report and review of the literature

Bait-Merabet, Lilia, Thille, Arnaud, Legrand, Patrick, Brun-Buisson, Christian, Cattoir, Vincent

Brachyspira pilosicoli is the etiologic agent of human and animal intestinal spirochetosis and is rarely implicated as a cause of bacteremia. Here, we describe the case of a B. pilosicoli...

Outpatient Antibiotic Use and Prevalence of Antibiotic-Resistant Pneumococci in France and Germany: A Sociocultural Perspective

Harbarth, Stephan, Albrich, Werner, Brun-Buisson, Christian

The prevalence of penicillin-nonsusceptible pneumococci is sharply divided between France (43%) and Germany (7%). These differences may be explained on different levels: antibiotic- prescribing...