Bjørndal, Lars, Reit, Claes, Bruun, Gitte, Markvart, Merete, Kjældgaard, Marianne, Näsman, Peggy, ...
Less invasive excavation methods have been suggested for deep caries lesions. We tested the effects of stepwise vs. direct complete excavation, 1 yr after the procedure had been carried out, in 314...
Wetterslev, Jørn, Thorlund, Kristian, Brok, Jesper, Gluud, Christian
Abstract Background There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect. The required information...
Kubiak, Christine, De Andres-Trelles, Fernando, Kuchinke, Wolfgang, Huemer, Karl-Heinz, Thirstrup, Steffen, Whitfield, Kate, ...
Abstract Background Thorough knowledge of the regulatory requirements is a challenging prerequisite for conducting multinational clinical studies in Europe given their complexity and heterogeneity in...
Knorr, Ulla, Vinberg, Maj, Klose, Marianne, Feldt-Rasmussen, Ulla, Hilsted, Linda, Gade, Anders, ...
Abstract Background Endophenotypes are heritable markers, which are more prevalent in patients and their healthy relatives than in the general population. Recent studies point at disturbed regulation...
Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? (2009)
Thorlund, Kristian, Devereaux, P J, Wetterslev, Jørn, Guyatt, Gordon, Ioannidis, John P A, Thabane, Lehana, ...
Background Results from apparently conclusive meta-analyses may be false. A limited number of events from a few small trials and the associated random error may be under-recognized sources of...
Brok, Jesper, Thorlund, Kristian, Wetterslev, Jørn, Gluud, Christian
Background Random error may cause misleading evidence in meta-analyses. The required number of participants in a meta-analysis (i.e. information size) should be at least as large as an adequately...
Kastrup, Jens, Johansen, Julia S., Winkel, Per, Hansen, Jørgen Fischer, Hildebrandt, Per, Jensen, Gorm Boje, ...
Aims Macrophages in atherosclerotic plaques secrete YKL-40. We tested the hypothesis if high serum YKL-40 concentration predicts coronary events and death of patients with stable coronary artery...
Hjorthøj, Carsten, Fohlmann, Allan, Larsen, Anne-Mette, Madsen, Mette TR, Vesterager, Lone, Gluud, Christian, ...
Abstract Background A number of studies indicate a link between cannabis-use and psychosis as well as more severe psychosis in those with existing psychotic disorders. There is currently insufficient...
EVIDENCE-BASED CLINICAL PRACTICE AND THE COCHRANE HEPATO-BILIARY GROUP (2008)
Christian Gluud, Dimitrinka Nikolova
The article gives an overview of the structure, aims, products, and achievements of The Cochrane Hepato-Biliary Group (CHBG) in its 12th-year of existence. The article informs about the process of...
Møller, Christian H., Penninga, Luit, Wetterslev, Jørn, Steinbrüchel, Daniel A., Gluud, Christian
Aims To assess the clinical outcomes of off- vs. on-pump coronary artery bypass surgery in randomized trials. Methods and results We searched electronic databases and bibliographies until June 2007....
Gluud, Christian, Nikolova, Dimitrinka
Abstract Background The number of publications on clinical trials is unknown as well as the countries publishing most trial reports. To try to examine these questions we performed an ecological...
PREVALENCE OF ALCOHOL PROBLEMS IN GENERAL PRACTICE: AN EXPERIENCE FROM SOUTHERN ITALY (1996)
RAMBALDI, ANDREA, TODISCO, NICOLA, GLUUD, CHRISTIAN, MBROSONE, LUCIA, RAMBALDI, MARIO
The Michigan Alcoholism Screening Test (MAST) and the response to a question about heavy alcohol consumption were used to assess the prevalence of alcohol problems in consecutive patients (77 males...
PREVALENCE OF ALCOHOL PROBLEMS AMONG ADULT SOMATIC IN-PATIENTS IN NAPLES (1995)
RAMBALDI, ANDREA, GLUUD, CHRISTIAN, BELLI, ANTONELLO, NIELSEN, SUSANNE D., STORGAARD, HEIDI, MOESGAARD, FLEMMING
The aim of this cross-sectional study was to determine the prevalence of alcohol problems among adult somatic in-patients in urban hospitals of Naples. The patients were screened with a structured...
META-ANALYSIS OF HLA-ANTIGEN PREVALENCES IN ALCOHOLICS AND ALCOHOLIC LIVER DISEASE (1994)
In the search for genetic factors influencing susceptibility to the development of alcoholism and alcoholic liver disease, 28 studies have been published analysing the distribution of human leucocyte...
THE VALIDITY OF THE MICHIGAN ALCOHOLISM SCREENING TEST (MAST) (1994)
STORGAARD, HEIDI, NIELSEN, SUSANNE D., GLUUD, CHRISTIAN
This review examines the validity of the Michigan Alcoholism Screening Test (MAST) as a screening instrument for alcohol problems. Studies that compare the MAST-questionnaire with other defined...
PREVALENCE OF ALCOHOL PROBLEMS AMONG ADULT SOMATIC IN-PATIENTS OF A COPENHAGEN HOSPITAL (1994)
NIELSEN, SUSANNE D., STORGAARD, HEIDI, MOESGAARD, FLEMMING, GLUUD, CHRISTIAN
The adult patients of somatic departments of a Copenhagen hospital were screened on a randomly selected day during a 14 day period by interviewers who examined them using a stnictured questionnaire...
PHYSICIAN'S INFORMATION ABOUT ALCOHOL PROBLEMS AT HOSPITALISATION OF ALCOHOL MISUSERS (1992)
NIELSEN, SUSANNE D., GLUUD, CHRISTIAN
Information was gathered on recognition and treatment of alcohol problems in the primary and secondary health sectors, the latter represented by a department of hepatology. The general practitioner...
Thesis (doctoral)--Københavns universitet, 1988.
Non-absorbable disaccharides for hepatic encephalopathy: systematic review of randomised trials
Als-Nielsen, Bodil, Gluud, Lise L, Gluud, Christian
Objective To assess the effects of non-absorbable disaccharides (lactulose and lactitol) in patients with hepatic encephalopathy.
Gluud, Christian, Gluud, Lise Lotte
Diagnostic tests are often much less rigorously evaluated than new drugs. It is time to ensure that the harms and benefits of new tests are fully understood
Krleža-Jerić, Karmela, Chan, An-Wen, Dickersin, Kay, Sim, Ida, Grimshaw, Jeremy, Gluud, Christian
Registering of trials is essential to make sure all results are publicly available and that ethical obligations to participants are met
Jespersen, Christian M, Als-Nielsen, Bodil, Damgaard, Morten, Hansen, Jørgen Fischer, Hansen, Stig, Helø, Olav H, ...
Objective To determine if the macrolide clarithromycin affects mortality and cardiovascular morbidity in patients with stable coronary heart disease.
Lee, Chuanfang, Gong, Yan, Brok, Jesper, Boxall, Elizabeth H, Gluud, Christian
Objective To evaluate the effects of hepatitis B vaccine and immunoglobulin in newborn infants of mothers positive for hepatitis B surface antigen.
Juul, Anne Benedicte, Wetterslev, Jørn, Gluud, Christian, Kofoed-Enevoldsen, Allan, Jensen, Gorm, Callesen, Torben, ...
Objectives To evaluate the long term effects of perioperative β blockade on mortality and cardiac morbidity in patients with diabetes undergoing major non-cardiac surgery.
Non-absorbable disaccharides for hepatic encephalopathy: systematic review of randomised trials
Als-Nielsen, Bodil, Gluud, Lise L, Gluud, Christian
Objective To assess the effects of non-absorbable disaccharides (lactulose and lactitol) in patients with hepatic encephalopathy.
Gluud, Christian, Gluud, Lise Lotte
Diagnostic tests are often much less rigorously evaluated than new drugs. It is time to ensure that the harms and benefits of new tests are fully understood
Krleža-Jerić, Karmela, Chan, An-Wen, Dickersin, Kay, Sim, Ida, Grimshaw, Jeremy, Gluud, Christian
Registering of trials is essential to make sure all results are publicly available and that ethical obligations to participants are met
Jespersen, Christian M, Als-Nielsen, Bodil, Damgaard, Morten, Hansen, Jørgen Fischer, Hansen, Stig, Helø, Olav H, ...
Objective To determine if the macrolide clarithromycin affects mortality and cardiovascular morbidity in patients with stable coronary heart disease.
Lee, Chuanfang, Gong, Yan, Brok, Jesper, Boxall, Elizabeth H, Gluud, Christian
Objective To evaluate the effects of hepatitis B vaccine and immunoglobulin in newborn infants of mothers positive for hepatitis B surface antigen.
Juul, Anne Benedicte, Wetterslev, Jørn, Gluud, Christian, Kofoed-Enevoldsen, Allan, Jensen, Gorm, Callesen, Torben, ...
Objectives To evaluate the long term effects of perioperative β blockade on mortality and cardiac morbidity in patients with diabetes undergoing major non-cardiac surgery.
Wood, Lesley, Egger, Matthias, Gluud, Lise Lotte, Schulz, Kenneth F, Jüni, Peter, Altman, Douglas G, ...
Objective To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the...
Hjorthøj, Carsten, Fohlmann, Allan, Larsen, Anne-Mette, Madsen, Mette TR, Vesterager, Lone, Gluud, Christian, ...
Boysen, Gudrun, Krarup, Lars-Henrik, Zeng, Xianrong, Oskedra, Adam, Kõrv, Janika, Andersen, Grethe, ...
Objectives To investigate if repeated verbal instructions about physical activity to patients with ischaemic stroke could increase long term physical activity.
Knorr, Ulla, Vinberg, Maj, Klose, Marianne, Feldt-Rasmussen, Ulla, Hilsted, Linda, Gade, Anders, ...
Kubiak, Christine, De Andres-Trelles, Fernando, Kuchinke, Wolfgang, Huemer, Karl-Heinz, Thirstrup, Steffen, Whitfield, Kate, ...