Bmc Bioinformatics, Federico E Turkheimer, Federico Roncaroli, Benoit Hennuy, Christian Herens, Minh Nguyen, ...
Research article Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas
Evidence for Neo-Generation of T Cells by the Thymus after Non-Myeloablative Conditioning (2008)
Castermans, Emilie, Baron, Frédéric, Willems, Evelyne, Schaaf, Nicole, Meuris, Nathalie, Gothot, André, ...
BACKGROUND: Background and objective. We investigated immune recovery in 50 patients given either unmanipulated or CD8-depleted allogeneic peripheral blood stem cells after non-myeloablative...
Willems, Evelyne, Baron, Frédéric, Baudoux, Etienne, Wanten, Nadine, Seidel, Laurence, Vanbellinghen, Jean-François, ...
Evidence for neo-generation of T cells by the thymus after non-myeloablative conditioning. (2008)
Castermans, Emilie, Baron, Frédéric, Willems, Evelyne, Schaaf, Nicole, Meuris, Nathalie, Gothot, André, ...
BACKGROUND: Background and objective. We investigated immune recovery in 50 patients given either unmanipulated or CD8-depleted allogeneic peripheral blood stem cells after non-myeloablative...
Herens, Christian, Lambert, Frédéric, Quintanilla-Martinez, Leticia, Bisig, Bettina, Deusings, CARINE, De Leval, Laurence
Lambert, Frédéric, Heimann, Pierre, Herens, Christian, Chariot, Alain, Bours, Vincent
The idiopathic hypereosinophilic syndrome (HES) has remained for a long time a diagnosis of exclusion. Differential diagnosis between the HES and the related chronic eosinophilic leukemia (CEL)...
Turkheimer, Federico E, Roncaroli, Federico, Hennuy, Benoit, Herens, Christian, Nguyen, Minh, Martin, Didier, ...
Abstract Background Expression microarrays represent a powerful technique for the simultaneous investigation of thousands of genes. The evidence that genes are not randomly distributed in the genome...
Thielen, Caroline, Herens, Christian, Fassotte, Marie-France, Detrooz, Elisabeth, Drion, Pierre, Diss, T, ...
Objectives: Burkitt's lymphoma (BL) is a highly aggressive mature B-cell neoplasm comprising endemic, sporadic and immunodeficiency-associated variants. Human cell lines constitute a very useful tool...
De Paepe, Pascale, Dastugue, Nicole, Bastard, Christian, Herens, Christian, ...
We present an extensive characterization of 10 B-cell lymphomas with a t(9;14)(p13;q32). The presence of the PAX5/IGH gene rearrangement was demonstrated by fluorescence in situ hybridization (FISH)...
Detry, Olivier, De Roover, Arnaud, De Leval, Laurence, Herens, Christian, Delwaide, Jean, Honore, Pierre, ...
Transmission of an undiagnosed cancer with solid organ transplantation is a rare but dreadful event. In this paper the authors report the transmission of an undiagnosed sarcoma to recipients of...
Baron, Frédéric, Baudoux, Etienne, Frere, Pascale, Tourqui, Soraya, Schaaf, Nicole, Herens, Christian, ...
We investigate the feasibility of CD34-selected peripheral blood stem cell (PBSC) transplantation followed by pre-emptive CD8-depleted donor lymphocyte infusions (DLI) after a minimal conditioning...
Herens, Christian, Baron, Frédéric, Croisiau, Christiane, Tassin, Françoise, Bours, Vincent
Imatinib mesylate (tested as STI571), an abl kinase inhibitor, induces sustained, complete hematologic and cytogenetic responses in chronic myelocytic leukemia (CML) patients; however, emergence of...
Detrembleur, Nancy, Delbecque, Katty, Thiry, Anne-Marie, Boniver, Jacques, Herens, Christian, Delvenne, Philippe
A 51-year old patient consults for abdominal swelling and persistent constipation. Clinical exploration shows the presence of a left iliac fossa tumor corresponding to a papillary serous...
Baron, Frédéric, Baudoux, Etienne, Frere, Pascale, Tourqui, Soraya, Schaaf, Nicole, Greimers, Roland, ...
To decrease the incidence of graft-versus-host disease (GVHD) observed after nonmyeloablative stem cell transplantation (NMSCT), we studied the feasibility of CD8-depleted or CD34-selected NMSCT...
Tassin, Françoise, Dewé, Walthère, Schaaf, Nicole, Herens, Christian, Ravoet, C, Albert, Adelin, ...
Marrow dysplasia is a major characteristic of patients with myelodysplastic syndrome (MDS), along with marrow blastosis, cytopenia and cytogenetic anomalies. However, the impact of the degree of...
Herens, Christian, Tassin, Françoise, Lemaire, Véronique, Beguin, Yves, Collard, E, Lampertz, S, ...
Inclusion of the BCR-ABL ES probe in routine cytogenetics led to the identification of a subgroup of Philadelphia positive (Ph+) chronic myeloid leukaemia patients characterized by a 5'-ABL deletion....
Translocation (2;3)(P21;Q26) as the Sole Anomaly in a Case of Primary Myelofibrosis (1999)
Herens, Christian, Hermanne, J P, Tassin, Françoise, Fassotte, M F, Thiry, Albert, Jamar, Michelle, ...
Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison...
Les syndromes myélodysplasiques: syndromes préleucémiques (1998)
Tassin, Françoise, Schaaf, Nicole, Herens, Christian, Thiry, Anne-Marie, Paulus, Jean-Michel, ...
The myelodysplastic syndromes (MDS) are a heterogeneous group of disorders characterized by peripheral blood cytopenias with a hypercellular bone marrow exhibiting dyspoiesis. The predominant in...
Herens, Christian, Jamar, Mauricette, Alvarez Gonzalez, Maria-Luz, Lesenfants, S, Lombet, Jacques, Bonnivert, Jacques, ...
In 1990, Lambotte syndrome was reported as an apparently autosomal recessive multiple congenital anomaly/mental retardation (MCA/MR) syndrome observed in 4 of 12 sibs from a probably consanguineous...
Herens, Christian, Alvarez Gonzalez, Maria-Luz, Barbason, Hervé
Cytogenetic analysis of rat hepatocarcinomas obtained after diethylnitrosamine (DEN) exposure showed a wide variety of numerical and structural chromosomal changes: 53 of 86 hepatocellular carcinomas...
Chromosome 22 Mosaic Monosomy (46,Xy/45,Xy,-22) (1987)
Verloes, Alain, Herens, Christian, Lambotte, C, Frederic, J
A slightly dysmorphic and mentally defective child with mosaic monosomy 22 is reported. Chromosome 22 is absent in 10.5% of lymphocytes and 8.3% of fibroblasts. This is the second case report of that...
Transgenic engineering of male-specific muscular hypertrophy
Pirottin, Dimitri, Grobet, Luc, Adamantidis, Antoine, Farnir, Frédéric, Herens, Christian, Schrøder, Henrik Daa, ...
Using a two-step procedure involving insertional gene targeting and recombinase-mediated cassette exchange in ES cells, we have produced two lines of transgenic mice expressing a dominant-negative...
Transgenic engineering of male-specific muscular hypertrophy
Pirottin, Dimitri, Grobet, Luc, Adamantidis, Antoine, Farnir, Frédéric, Herens, Christian, Schrøder, Henrik Daa, ...
Using a two-step procedure involving insertional gene targeting and recombinase-mediated cassette exchange in ES cells, we have produced two lines of transgenic mice expressing a dominant-negative...
Turkheimer, Federico E, Roncaroli, Federico, Hennuy, Benoit, Herens, Christian, Nguyen, Minh, Martin, Didier, ...
A Case of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia with a Rare FIP1L1 Breakpoint
Lambert, Frédéric, Heimann, Pierre, Herens, Christian, Chariot, Alain, Bours, Vincent
The idiopathic hypereosinophilic syndrome (HES) has remained for a long time a diagnosis of exclusion. Differential diagnosis between the HES and the related chronic eosinophilic leukemia (CEL)...