Fourmidable: a database for ant genomics (2009)
Wurm, Yannick, Uva, Paolo, Ricci, Frédéric, Wang, John, Jemielity, Stephanie, Iseli, Christian, ...
Abstract Background Fourmidable is an infrastructure to curate and share the emerging genetic, molecular, and functional genomic data and protocols for ants. Description The Fourmidable assembly...
Probabilistic base calling of Solexa sequencing data (2008)
Rougemont, Jacques, Amzallag, Arnaud, Iseli, Christian, Farinelli, Laurent, Xenarios, Ioannis, Naef, Felix
Abstract Background Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA colonies....
Christian Iseli, C. Victor Jongeneel
One of the problems associated with the large-scale analysis of unannotated, low quality EST sequences is the detection of coding regions and the correction of frameshift errors that they often...
Rapid evolution of cancer/testis genes on the X chromosome (2007)
Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, ...
Abstract Background Cancer/testis (CT) genes are normally expressed only in germ cells, but can be activated in the cancer state. This unusual property, together with the finding that many CT...
Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, ...
Abstract Introduction Diverse microarray and sequencing technologies have been widely used to characterise the molecular changes in malignant epithelial cells in breast cancers. Such gene expression...
Similarities and differences of polyadenylation signals in human and fly (2006)
Retelska, Dorota, Iseli, Christian, Bucher, Philipp, Jongeneel, C Victor, Naef, Felix
Abstract Background Cleavage of messenger RNA (mRNA) precursors is an essential step in mRNA maturation. The signal recognized by the cleavage enzyme complex has been characterized as an A rich...
An atlas of human gene expression from massively parallel signature sequencing (MPSS) (2005)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
trome, trEST and trGEN: databases of predicted protein sequences (2004)
Sperisen, Peter, Iseli, Christian, Pagni, Marco, Stevenson, Brian J., Bucher, Philipp, Jongeneel, C. Victor
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these...
Long-Range Heterogeneity at the 3' Ends of Human mRNAs (2002)
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
Long-Range Heterogeneity at the 3' Ends of Human mRNAs (2002)
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
trEST, trGEN and Hits: access to databases of predicted protein sequences (2001)
Pagni, Marco, Iseli, Christian, Junier, Thomas, Falquet, Laurent, Jongeneel, Victor, Bucher, Philipp
High throughput genome (HTG) and expressed sequence tag (EST) sequences are currently the most abundant nucleotide sequence classes in the public database. The large volume, high degree of...
A cSNP Map and Database for Human Chromosome 21 (2001)
Deutsch, Samuel, Iseli, Christian, Bucher, Philipp, Antonarakis, Stylianos E., Scott, Hamish S.
A cSNP Map and Database for Human Chromosome 21 (2001)
Deutsch, Samuel, Iseli, Christian, Bucher, Philipp, Antonarakis, Stylianos E., Scott, Hamish S.
A cSNP Map and Database for Human Chromosome 21 (2001)
Deutsch, Samuel, Iseli, Christian, Bucher, Philipp, Antonarakis, Stylianos E., Scott, Hamish S.
Spyder: a reconfigurable processor development system (1996)
The Spyder project consists of the development of a reconfigurable processor as well as its application development environment. The name Spyder is an anagram of the first letters of "REconfigurable...
trEST, trGEN and Hits: access to databases of predicted protein sequences
Pagni, Marco, Iseli, Christian, Junier, Thomas, Falquet, Laurent, Jongeneel, Victor, Bucher, Philipp
High throughput genome (HTG) and expressed sequence tag (EST) sequences are currently the most abundant nucleotide sequence classes in the public database. The large volume, high degree of...
Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, ...
Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in...
Long-Range Heterogeneity at the 3′ Ends of Human mRNAs
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
The publication of a draft of the human genome and of large collections of transcribed sequences has made it possible to study the complex relationship between the transcriptome and the genome. In...
Brentani, Helena, Caballero, Otávia L., Camargo, Anamaria A., Da Silva, Aline M., Da Silva, Wilson Araújo, Neto, Emmanuel Dias, ...
Whereas genome sequencing defines the genetic potential of an organism, transcript sequencing defines the utilization of this potential and links the genome with most areas of biology. To exploit the...
trome, trEST and trGEN: databases of predicted protein sequences
Sperisen, Peter, Iseli, Christian, Pagni, Marco, Stevenson, Brian J., Bucher, Philipp, Jongeneel, C. Victor
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these...
A cSNP Map and Database for Human Chromosome 21
Deutsch, Samuel, Iseli, Christian, Bucher, Philipp, Antonarakis, Stylianos E., Scott, Hamish S.
Single nucleotide polymorphisms (SNPs) are likely to contribute to the study of complex genetic diseases. The genomic sequence of human chromosome 21q was recently completed with 225 annotated genes,...
Identification of cancer/testis-antigen genes by massively parallel signature sequencing
Chen, Yao-Tseng, Scanlan, Matthew J., Venditti, Charis A., Chua, Ramon, Theiler, Gregory, Stevenson, Brian J., ...
Massively parallel signature sequencing (MPSS) generates millions of short sequence tags corresponding to transcripts from a single RNA preparation. Most MPSS tags can be unambiguously assigned to...
An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
Similarities and differences of polyadenylation signals in human and fly
Retelska, Dorota, Iseli, Christian, Bucher, Philipp, Jongeneel, C Victor, Naef, Felix
trEST, trGEN and Hits: access to databases of predicted protein sequences
Pagni, Marco, Iseli, Christian, Junier, Thomas, Falquet, Laurent, Jongeneel, Victor, Bucher, Philipp
High throughput genome (HTG) and expressed sequence tag (EST) sequences are currently the most abundant nucleotide sequence classes in the public database. The large volume, high degree of...
Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, ...
Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in...
Long-Range Heterogeneity at the 3′ Ends of Human mRNAs
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
The publication of a draft of the human genome and of large collections of transcribed sequences has made it possible to study the complex relationship between the transcriptome and the genome. In...
Brentani, Helena, Caballero, Otávia L., Camargo, Anamaria A., Da Silva, Aline M., Da Silva, Wilson Araújo, Neto, Emmanuel Dias, ...
Whereas genome sequencing defines the genetic potential of an organism, transcript sequencing defines the utilization of this potential and links the genome with most areas of biology. To exploit the...
trome, trEST and trGEN: databases of predicted protein sequences
Sperisen, Peter, Iseli, Christian, Pagni, Marco, Stevenson, Brian J., Bucher, Philipp, Jongeneel, C. Victor
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these...
A cSNP Map and Database for Human Chromosome 21
Deutsch, Samuel, Iseli, Christian, Bucher, Philipp, Antonarakis, Stylianos E., Scott, Hamish S.
Single nucleotide polymorphisms (SNPs) are likely to contribute to the study of complex genetic diseases. The genomic sequence of human chromosome 21q was recently completed with 225 annotated genes,...
Identification of cancer/testis-antigen genes by massively parallel signature sequencing
Chen, Yao-Tseng, Scanlan, Matthew J., Venditti, Charis A., Chua, Ramon, Theiler, Gregory, Stevenson, Brian J., ...
Massively parallel signature sequencing (MPSS) generates millions of short sequence tags corresponding to transcripts from a single RNA preparation. Most MPSS tags can be unambiguously assigned to...
An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
Similarities and differences of polyadenylation signals in human and fly
Retelska, Dorota, Iseli, Christian, Bucher, Philipp, Jongeneel, C Victor, Naef, Felix
Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, ...
Rapid evolution of cancer/testis genes on the X chromosome
Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, ...
Indexing Strategies for Rapid Searches of Short Words in Genome Sequences
Iseli, Christian, Ambrosini, Giovanna, Bucher, Philipp, Jongeneel, C. Victor
Searching for matches between large collections of short (14–30 nucleotides) words and sequence databases comprising full genomes or transcriptomes is a common task in biological sequence analysis....
Probabilistic base calling of Solexa sequencing data
Rougemont, Jacques, Amzallag, Arnaud, Iseli, Christian, Farinelli, Laurent, Xenarios, Ioannis, Naef, Felix
Fourmidable: a database for ant genomics
Wurm, Yannick, Uva, Paolo, Ricci, Frédéric, Wang, John, Jemielity, Stephanie, Iseli, Christian, ...
Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line
Zhao, Qi, Caballero, Otavia L., Levy, Samuel, Stevenson, Brian J., Iseli, Christian, De Souza, Sandro J., ...
We have identified new genomic alterations in the breast cancer cell line HCC1954, using high-throughput transcriptome sequencing. With 120 Mb of cDNA sequences, we were able to identify genomic...
Detection of Genomic Variation by Selection of a 9 Mb DNA Region and High Throughput Sequencing
Nikolaev, Sergey I., Iseli, Christian, Sharp, Andrew J., Robyr, Daniel, Rougemont, Jacques, Gehrig, Corinne, ...
Detection of the rare polymorphisms and causative mutations of genetic diseases in a targeted genomic area has become a major goal in order to understand genomic and phenotypic variability. We have...