Large-scale mapping of mutations affecting zebrafish development (2007)
Geisler, Robert, Rauch, Gerd-Jörg, Geiger-Rudolph, Silke, Albrecht, Andrea, Van Bebber, Frauke, Berger, Andrea, ...
Abstract Background Large-scale mutagenesis screens in the zebrafish employing the mutagen ENU have isolated several hundred mutant loci that represent putative developmental control genes. In order...
Large-scale mapping of mutations affecting zebrafish development. (2007)
Geisler, Robert, Rauch, Joerg, Geiger-Rudolph, Silke, Albrecht, A., Van Bebber, Frauke, Berger, Andrea, ...
Moussian, Bernard, Tang, E., Tonning, A., Helms, Sigrun, Schwarz, Heinz, Nüsslein-Volhard, Christiane, ...
Precise epithelial tube diameters rely on coordinated cell shape changes and apical membrane enlargement during tube growth. Uniform tube expansion in the developing Drosophila trachea requires the...
Vogt, Nina, Koch, Iris, Schwarz, Heinz, Schnorrer, Frank, Nüsslein-Volhard, Christiane
The gamma-tubulin ring complex (gammaTuRC) forms an essential template for microtubule nucleation in animal cells. The molecular composition of the gammaTuRC has been described; however, the...
Luschnig,Stefan, Moussian,Bernard, Krauss,Jana, Desjeux,Isabelle, Perkovic,Josip, Nüsslein-Volhard,Christiane
Large-scale screens for female-sterile mutations have revealed genes required maternally for establishment of the body axes in the Drosophila embryo. Although it is likely that the majority of...
Towing of sensory axons by their migrating target cells in vivo (2004)
Gilmour,Darren, Knaut,Holger, Maischein,Hans-Martin, Nüsslein-Volhard,Christiane
Many pathfinding axons must locate target fields that are themselves positioned by active migration. A hypothetical method for ensuring that these migrations are coordinated is towing, whereby the...
Luschnig, Stefan, Moussian, Bernard, Krauss, Jana, Desjeux, Isabelle, Perkovic, Josip, Nüsslein-Volhard, Christiane
Large-scale screens for female-sterile mutations have revealed genes required maternally for establishment of the body axes in the Drosophila embryo. Although it is likely that the majority of...
Towing of sensory axons by their migrating target cells in vivo (2004)
Gilmour, Darren, Knaut, Holger, Maischein, Hans-Martin, Nüsslein-Volhard, Christiane
Many pathfinding axons must locate target fields that are themselves positioned by active migration. A hypothetical method for ensuring that these migrations are coordinated is towing, whereby the...
Dekens,Marcus, Pelegri,Francesco, Maischein,Hans-Martin, Nüsslein-Volhard,Christiane
Embryos have been successfully used for the general study of the cell cycle. Although there are significant differences between the early embryonic and the somatic cell cycle in vertebrates, the...
Maderspacher,Florian, Nüsslein-Volhard,Christiane
Colour patterns are a prominent feature of many animals and are of high evolutionary relevance. In zebrafish, the adult pigment pattern comprises alternating stripes of two pigment cell types,...
Dekens, Marcus, Pelegri, Francesco, Maischein, Hans-Martin, Nüsslein-Volhard, Christiane
Embryos have been successfully used for the general study of the cell cycle. Although there are significant differences between the early embryonic and the somatic cell cycle in vertebrates, the...
Maderspacher, Florian, Nüsslein-Volhard, Christiane
Colour patterns are a prominent feature of many animals and are of high evolutionary relevance. In zebrafish, the adult pigment pattern comprises alternating stripes of two pigment cell types,...
Zebrafish - A Practical Approach. (2002)
Nüsslein-Volhard, Christiane, Dahm, Ralf
The zebrafish offers numerous advantages to researchers interested in embryonic development, physiology and disease. In the next few years the entire zebrafish genome will be sequenced, and several...
Zebrafish as a system to study development and organogenesis (2002)
Nüsslein-Volhard, Christiane, Gilmour, Darren T., Dahm, Ralf
Holley, Scott A., Geisler, Robert, Nüsslein-Volhard, Christiane
Somitogenesis has been linked both to a molecular clock that controls the oscillation of gene expression in the presomitic mesoderm (PSM) and to Notch pathway signaling. The oscillator, or clock, is...
Santamaria, Pedro, Nüsslein-Volhard, Christiane
Mutant alleles at the maternal effect locus dorsal cause a dorsalization of the Drosophila embryo. In extreme mutants, the embryos develop exclusively structures which derive from the dorsal-most...
The Genetics of the DORSAL-BICAUDAL-D Region of DROSOPHILA MELANOGASTER
Steward, Ruth, Nüsslein-Volhard, Christiane
The chromosomal region 36C on 2L contains two maternal-effect loci, dorsal (dl) and Bicaudal-D (Bic-D), which are involved in establishing polarity of the Drosophila embryo along the dorsal-ventral...
Luschnig, Stefan, Moussian, Bernard, Krauss, Jana, Desjeux, Isabelle, Perkovic, Josip, Nüsslein-Volhard, Christiane
Large-scale screens for female-sterile mutations have revealed genes required maternally for establishment of the body axes in the Drosophila embryo. Although it is likely that the majority of...
Holley, Scott A., Geisler, Robert, Nüsslein-Volhard, Christiane
Somitogenesis has been linked both to a molecular clock that controls the oscillation of gene expression in the presomitic mesoderm (PSM) and to Notch pathway signaling. The oscillator, or clock, is...
Santamaria, Pedro, Nüsslein-Volhard, Christiane
Mutant alleles at the maternal effect locus dorsal cause a dorsalization of the Drosophila embryo. In extreme mutants, the embryos develop exclusively structures which derive from the dorsal-most...
The Genetics of the DORSAL-BICAUDAL-D Region of DROSOPHILA MELANOGASTER
Steward, Ruth, Nüsslein-Volhard, Christiane
The chromosomal region 36C on 2L contains two maternal-effect loci, dorsal (dl) and Bicaudal-D (Bic-D), which are involved in establishing polarity of the Drosophila embryo along the dorsal-ventral...
Luschnig, Stefan, Moussian, Bernard, Krauss, Jana, Desjeux, Isabelle, Perkovic, Josip, Nüsslein-Volhard, Christiane
Large-scale screens for female-sterile mutations have revealed genes required maternally for establishment of the body axes in the Drosophila embryo. Although it is likely that the majority of...
Large-scale mapping of mutations affecting zebrafish development
Geisler, Robert, Rauch, Gerd-Jörg, Geiger-Rudolph, Silke, Albrecht, Andrea, Van Bebber, Frauke, Berger, Andrea, ...
Wilsch-Bräuninger, Michaela, Schwarz, Heinz, Nüsslein-Volhard, Christiane
Localization of maternally provided RNAs during oogenesis is required for formation of the antero–posterior axis of the Drosophila embryo. Here we describe a subcellular structure in nurse cells...
Knaut, Holger, Pelegri, Francisco, Bohmann, Kerstin, Schwarz, Heinz, Nüsslein-Volhard, Christiane
Work in different organisms revealed that the vasa gene product is essential for germline specification. Here, we describe the asymmetric segregation of zebrafish vasa RNA, which distinguishes germ...
Harris, Matthew P., Rohner, Nicolas, Schwarz, Heinz, Perathoner, Simon, Konstantinidis, Peter, Nüsslein-Volhard, Christiane
The genetic basis of the development and variation of adult form of vertebrates is not well understood. To address this problem, we performed a mutant screen to identify genes essential for the...
Reischauer, Sven, Levesque, Mitchell P., Nüsslein-Volhard, Christiane, Sonawane, Mahendra
Changes in tissue homeostasis, acquisition of invasive cell characteristics, and tumor formation can often be linked to the loss of epithelial cell polarity. In carcinogenesis, the grade of neoplasia...