Christie G. Brouillette

Dimethyl sulfoxide at 2.5% (v/v) alters the structural cooperativity and unfolding mechanism of dimeric bacterial NAD+ synthetase (2004)

Yang, Zhengrong W., Tendian, Susan W., Carson, W. Michael, Brouillette, Wayne J., Delucas, Lawrence J., Brouillette, Christie G.

Dimethyl sulfoxide (DMSO) is commonly used as a cosolvent to improve the aqueous solubility of small organic compounds. Its use in a screen to identify novel inhibitors of the enzyme NAD+ synthetase...

Down-Regulation of Cell Surface Receptors Is Modulated by Polar Residues within the Transmembrane Domain

Zaliauskiene, Lolita, Kang, Sunghyun, Brouillette, Christie G., Lebowitz, Jacob, Arani, Ramin B., Collawn, James F.

How recycling receptors are segregated from down-regulated receptors in the endosome is unknown. In previous studies, we demonstrated that substitutions in the transferrin receptor (TR) transmembrane...

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

Borhani, David W., Rogers, Danise P., Engler, Jeffrey A., Brouillette, Christie G.

The structure of truncated human apolipoprotein A-I (apo A-I), the major protein component of high density lipoprotein, has been determined at 4-Å resolution. The crystals comprise residues...

Structural Domains in Vesicular Stomatitis Virus Membrane as Studied by Differential Scanning Calorimetry

Brouillette, Christie G., Compans, Richard W., Segrest, Jere P., Brandts, John F.

Dynamics of Apolipoprotein-Phospholipid Interactions

Brouillette, Christie G., Segrest, Jere P., Ng, Thian, Chung, Byung Hong, Ragland, James B.

Down-Regulation of Cell Surface Receptors Is Modulated by Polar Residues within the Transmembrane Domain

Zaliauskiene, Lolita, Kang, Sunghyun, Brouillette, Christie G., Lebowitz, Jacob, Arani, Ramin B., Collawn, James F.

How recycling receptors are segregated from down-regulated receptors in the endosome is unknown. In previous studies, we demonstrated that substitutions in the transferrin receptor (TR) transmembrane...

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

Borhani, David W., Rogers, Danise P., Engler, Jeffrey A., Brouillette, Christie G.

The structure of truncated human apolipoprotein A-I (apo A-I), the major protein component of high density lipoprotein, has been determined at 4-Å resolution. The crystals comprise residues...

Structural Domains in Vesicular Stomatitis Virus Membrane as Studied by Differential Scanning Calorimetry

Brouillette, Christie G., Compans, Richard W., Segrest, Jere P., Brandts, John F.

Dynamics of Apolipoprotein-Phospholipid Interactions

Brouillette, Christie G., Segrest, Jere P., Ng, Thian, Chung, Byung Hong, Ragland, James B.

Dimethyl sulfoxide at 2.5% (v/v) alters the structural cooperativity and unfolding mechanism of dimeric bacterial NAD+ synthetase

Yang, Zhengrong W., Tendian, Susan W., Carson, W. Michael, Brouillette, Wayne J., Delucas, Lawrence J., Brouillette, Christie G.

Dimethyl sulfoxide (DMSO) is commonly used as a cosolvent to improve the aqueous solubility of small organic compounds. Its use in a screen to identify novel inhibitors of the enzyme NAD+ synthetase...

Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis

Lu, Shanyun, Smith, Craig D., Yang, Zhengrong, Pruett, Pamela S., Nagy, Lisa, McCombs, Deborah, ...

The crystal structure of apo nicotinic acid mononucleotide adenylyltransferase (NaMNAT) from B. anthracis was determined to 2.3 Å resolution and compared with other bacterial NaMNAT structures.