Keller, Andreas, Backes, Christina, Gerasch, Andreas, Kaufmann, Michael, Kohlbacher, Oliver, Meese, Eckart, ...
Motivation: Deregulated signaling cascades are known to play a crucial role in many pathogenic processes, among them are tumor initiation and progression. In the recent past, modern experimental...
Keller, Andreas, Backes, Christina, Al-Awadhi, Maher, Gerasch, Andreas, Küntzer, Jan, Kohlbacher, Oliver, ...
Abstract Background High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical processes. While...
Pierre Dönnes, Annette Höglund, Marc Sturm, Nicole Comtesse, Christina Backes, Eckart Meese, ...
The development of human cancer is a highly complex process and can be considered the result of several combined events, such as genetic alterations, disturbance of signal transduction, or failure of...
HP: GeneTrail – advanced gene set enrichment analysis (2008)
Christina Backes, Andreas Keller, Jan Kuentzer, Benny Kneissl, Nicole Comtesse, Yasser A. Elnakady, ...
We present a comprehensive and efficient gene set analysis tool, called ‘GeneTrail ’ that offers a rich functionality and is easy to use. Our web-based application facilitates the statistical...
HP: GeneTrail – advanced gene set enrichment analysis (2008)
Christina Backes, Andreas Keller, Jan Kuentzer, Benny Kneissl, Nicole Comtesse, Yasser A. Elnakady, ...
We present a comprehensive and efficient gene set analysis tool, called ‘GeneTrail ’ that offers a rich functionality and is easy to use. Our web-based application facilitates the statistical...
BN++- A Biological Information System (2008)
Jan Küntzer, Torsten Blum, Andreas Gerasch, Christina Backes, Michael Kaufmann, Oliver Kohlbacher, ...
Recent years have seen an explosive growth in the amount of biochemical data available. Numerous databases have been established and are being used as an essential resource by biologists around the...
Bmc Bioinformatics, Andreas Keller, Christina Backes, Maher Al-awadhi, Andreas Gerasch, Jan Küntzer, ...
Software GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments
BNDB – The Biochemical Network Database (2007)
Küntzer, Jan, Backes, Christina, Blum, Torsten, Gerasch, Andreas, Kaufmann, Michael, Kohlbacher, Oliver, ...
Abstract Background Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored in numerous...
Computation of significance scores of unweighted Gene Set Enrichment Analyses (2007)
Keller, Andreas, Backes, Christina, Lenhof, Hans-Peter
Abstract Background Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for interpreting...
GeneTrail--advanced gene set enrichment analysis (2007)
Backes, Christina, Keller, Andreas, Kuentzer, Jan, Kneissl, Benny, Comtesse, Nicole, Elnakady, Yasser A., ...
We present a comprehensive and efficient gene set analysis tool, called ‘GeneTrail’ that offers a rich functionality and is easy to use. Our web-based application facilitates the statistical...
Andreas Keller, Christina Backes, Hans-peter Lenhof
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for interpreting...
BMC Bioinformatics Database BNDB – The Biochemical Network Database (2007)
Jan Küntzer, Christina Backes, Torsten Blum, Andreas Gerasch, Michael Kaufmann, Oliver Kohlbacher, ...
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored in numerous...
BN++ - A Biological Information System (2006)
Küntzer, Jan, Blum, Torsten, Gerasch, Andreas, Backes, Christina, Hildebrandt, Andreas, Kaufmann, Michael, ...
Recent years have seen an explosive growth in the amount of biochemical data available. Numerous databases have been established and are being used as an essential resource by biologists around the...
prediction of Caspase- and Granzyme B-cleavage (2005)
Christina Backes, Jan Kuentzer, Hans-peter Lenhof, Nicole Comtesse, Eckart Meese
sites in protein sequences
Backes, Christina, Kuentzer, Jan, Lenhof, Hans-Peter, Comtesse, Nicole, Meese, Eckart
Caspases and granzyme B are proteases that share the primary specificity to cleave at the carboxyl terminal of aspartate residues in their substrates. Both, caspases and granzyme B are enzymes that...
Backes, Christina, Kuentzer, Jan, Lenhof, Hans-Peter, Comtesse, Nicole, Meese, Eckart
Caspases and granzyme B are proteases that share the primary specificity to cleave at the carboxyl terminal of aspartate residues in their substrates. Both, caspases and granzyme B are enzymes that...
Comtesse, Nicole, Zippel, Andrea, Walle, Sascha, Monz, Dominik, Backes, Christina, Fischer, Ulrike, ...
There are numerous studies on the immune response against malignant human tumors. This study was aimed to address the complexity and specificity of humoral immune response against a benign human...
Backes, Christina, Kuentzer, Jan, Lenhof, Hans-Peter, Comtesse, Nicole, Meese, Eckart
Caspases and granzyme B are proteases that share the primary specificity to cleave at the carboxyl terminal of aspartate residues in their substrates. Both, caspases and granzyme B are enzymes that...
Comtesse, Nicole, Zippel, Andrea, Walle, Sascha, Monz, Dominik, Backes, Christina, Fischer, Ulrike, ...
There are numerous studies on the immune response against malignant human tumors. This study was aimed to address the complexity and specificity of humoral immune response against a benign human...
GeneTrail—advanced gene set enrichment analysis
Backes, Christina, Keller, Andreas, Kuentzer, Jan, Kneissl, Benny, Comtesse, Nicole, Elnakady, Yasser A., ...
We present a comprehensive and efficient gene set analysis tool, called ‘GeneTrail’ that offers a rich functionality and is easy to use. Our web-based application facilitates the statistical...