Christina L. Boulton

PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRalpha-induced myeloproliferative disease (2003)

Stover, Elizabeth H, Boulton, Christina L, Gotlib, Jason, Legare, Robert D, Amaral, Sonia M, ...

FIP1L1-PDGFRalpha causes hypereosinophilic syndrome (HES) and is inhibited by the tyrosine kinase inhibitor imatinib (Gleevec). Imatinib is a potent inhibitor of ABL, ARG, PDGFRalpha, PDGFRbeta, and...

PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model

Kelly, Louise M., Kutok, Jeffrey L., Williams, Ifor R., Boulton, Christina L., Amaral, Sonia M., Curley, David P., ...

Acute promyelocytic leukemia (APL) cells invariably express aberrant fusion proteins involving the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic leukemia protein...

A large-scale screen for mutagen-sensitive loci in Drosophila.

Laurencon, Anne, Orme, Charisse M, Peters, Heather K, Boulton, Christina L, Vladar, Eszter K, Langley, Sasha A, ...

In a screen for new DNA repair mutants, we tested 6275 Drosophila strains bearing homozygous mutagenized autosomes (obtained from C. Zuker) for hypersensitivity to methyl methanesulfonate (MMS) and...

PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model

Kelly, Louise M., Kutok, Jeffrey L., Williams, Ifor R., Boulton, Christina L., Amaral, Sonia M., Curley, David P., ...

Acute promyelocytic leukemia (APL) cells invariably express aberrant fusion proteins involving the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic leukemia protein...

A large-scale screen for mutagen-sensitive loci in Drosophila.

Laurencon, Anne, Orme, Charisse M, Peters, Heather K, Boulton, Christina L, Vladar, Eszter K, Langley, Sasha A, ...

In a screen for new DNA repair mutants, we tested 6275 Drosophila strains bearing homozygous mutagenized autosomes (obtained from C. Zuker) for hypersensitivity to methyl methanesulfonate (MMS) and...