Christine Canning

Corresponding Author: (2005)

Roberto Bellucci, Edwin P Alyea, Sabina Chiaretti, Catherine J Wu, Emmanuel Zorn, Edie Weller, ...

doi:10.1182/blood-2004-11-4463 Graft versus tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma cell membrane receptor

CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia

Yang, Xiao-Feng, Wu, Catherine J., McLaughlin, Stephen, Chillemi, Antoinette, Wang, Kathy S., Canning, Christine, ...

This report describes a tumor-associated antigen, termed CML66, initially cloned from a chronic myelogenous leukemia (CML) cDNA expression library. CML66 encodes a 583-aa protein with a molecular...

Detection of a potent humoral response associated with immune-induced remission of chronic myelogenous leukemia

Wu, Catherine J., Yang, Xiao-Feng, McLaughlin, Stephen, Neuberg, Donna, Canning, Christine, Stein, Brady, ...

The effectiveness of donor-lymphocyte infusion (DLI) for treatment of relapsed chronic myelogenous leukemia (CML) after allogeneic bone marrow transplantation is a clear demonstration of the...

CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia

Yang, Xiao-Feng, Wu, Catherine J., McLaughlin, Stephen, Chillemi, Antoinette, Wang, Kathy S., Canning, Christine, ...

This report describes a tumor-associated antigen, termed CML66, initially cloned from a chronic myelogenous leukemia (CML) cDNA expression library. CML66 encodes a 583-aa protein with a molecular...

Detection of a potent humoral response associated with immune-induced remission of chronic myelogenous leukemia

Wu, Catherine J., Yang, Xiao-Feng, McLaughlin, Stephen, Neuberg, Donna, Canning, Christine, Stein, Brady, ...

The effectiveness of donor-lymphocyte infusion (DLI) for treatment of relapsed chronic myelogenous leukemia (CML) after allogeneic bone marrow transplantation is a clear demonstration of the...

Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor

Bellucci, Roberto, Alyea, Edwin P., Chiaretti, Sabina, Wu, Catherine J., Zorn, Emmanuel, Weller, Edie, ...

Donor lymphocyte infusions (DLIs) induce effective graft-versus-tumor responses in patients with multiple myeloma who relapse after allogeneic hematopoietic stem-cell transplantation. The...

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

Zorn, Emmanuel, Nelson, Erik A., Mohseni, Mehrdad, Porcheray, Fabrice, Kim, Haesook, Litsa, Despina, ...

IL-2 plays a critical role in the maintenance of CD4+CD25+ FOXP3+ regulatory T cells (Tregs) in vivo. We examined the effects of IL-2 signaling in human Tregs. In vitro, IL-2 selectively up-regulated...

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

Hodi, F. Stephen, Butler, Marcus, Oble, Darryl A., Seiden, Michael V., Haluska, Frank G., Kruse, Andrea, ...

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) functions as a negative regulator of endogenous and vaccine-induced antitumor immunity. The administration of fully human anti-CTLA-4 blocking...