Christine L. Powell

Multicenter Study of Acetaminophen Hepatotoxicity Reveals the Importance of Biological Endpoints in Genomic Analyses (2007)

Beyer, Richard P., Fry, Rebecca C., Lasarev, Michael R., McConnachie, Lisa A., Meira, Lisiane B., Palmer, Valerie S., ...

Gene expression profiling is a widely used technique with data from the majority of published microarray studies being publicly available. These data are being used for meta-analyses and in silico...

Phenotypic Anchoring of Acetaminophen-Induced Oxidative Stress with Gene Expression Profiles in Rat Liver (2006)

Powell, Christine L., Kosyk, Oksana, Ross, Pamela K., Schoonhoven, Robert, Boysen, Gunnar, Swenberg, James A., ...

Toxicogenomics provides the ability to examine in greater detail the underlying molecular events that precede and accompany toxicity, thus allowing prediction of adverse events at much earlier times...

Phenotypic Anchoring of Acetaminophen-Induced Oxidative Stress with Gene Expression Profiles in Rat Liver (2006)

Powell, Christine L., Kosyk, Oksana, Ross, Pamela K., Schoonhoven, Robert, Boysen, Gunnar, Swenberg, James A., ...

Toxicogenomics provides the ability to examine in greater detail the underlying molecular events that precede and accompany toxicity, thus allowing prediction of adverse events at much earlier times...

Lipids versus Proteins as Major Targets of Pro-Oxidant, Direct-Acting Hemolytic Agents (2005)

McMillan, David C., Powell, Christine L., Bowman, Zachary S., Morrow, Jason D., Jollow, David J.

Lipid peroxidation and the accompanying translocation of phosphatidylserine (PS) from the inner to the outer leaflet of the lipid bilayer have recently been identified as key components of a...