Christine Margaret Boyle

Basic mechanisms of DNA-raised antibody responses to intramuscular and gene gun immunizations (2000)

Boyle, Christine Margaret, Robinson, Harriet L.

DNA-raised antibody (Ab) responses have been compared for the dependence on CD4+ and CD8+ cells, the longevity of functional antigen (Ag) expression, and the nature of the Ag-presenting cell after...

DNA Immunization: Basic Mechanisms of the DNA-Raised Antibody Response Using an Influenza Hemagglutinin-Expressing Plasmid: A Dissertation (2000)

Boyle, Christine Margaret

In DNA immunization a plasmid expressing an antigen of interest is inoculated into an animal and antigen-specific humoral and cellular immune responses are raised. In this dissertation we sought to...

DNA immunization for influenza virus: studies using hemagglutinin- and nucleoprotein-expressing DNAs (1997)

Robinson, Harriet L., Boyle, Christine Margaret, Feltquate, David Marc, Morin, Merribeth J., Santoro, Joseph C., Webster, Robert G.

DNA-based immunizations have been used to analyze the ability of DNA-expressed hemagglutinin (HA) and nucleoprotein (NP) to protect BALB/c mice against a homologous influenza virus, A/PR/8/34 (H1N1),...

Role of different lymphoid tissues in the initiation and maintenance of DNA-raised antibody responses to the influenza virus H1 glycoprotein (1996)

Boyle, Christine Margaret, Morin, Merribeth J., Webster, Robert G., Robinson, Harriet L.

Antibody responses in mice immunized by a single gene gun inoculation of plasmid expressing the influenza virus H1 hemagglutinin and in mice immunized by a sublethal H1 influenza virus infection have...