Christophe d'Enfert

A Human-Curated Annotation of the Candida albicans Genome (2005)

Burkhard R. Braun, Christophe D'Enfert, Mikhail Martchenko, Jan Dungan, Alan Kuo, ...

Recent sequencing and assembly of the genome for the fungal pathogen Candida albicans used simple automated procedures for the identification of putative genes. We have reviewed the entire assembly,...

Candida albicans Biofilms: a Developmental State Associated With Specific and Stable Gene Expression Patterns

García-Sánchez, Susana, Aubert, Sylvie, Iraqui, Ismaïl, Janbon, Guilhem, Ghigo, Jean-Marc, D'Enfert, Christophe

Like many bacteria, yeast species can form biofilms on several surfaces. Candida albicans colonizes the surfaces of catheters, prostheses, and epithelia, forming biofilms that are extremely resistant...

A Human-Curated Annotation of the Candida albicans Genome

Braun, Burkhard R, Van Het Hoog, Marco, D'Enfert, Christophe, Martchenko, Mikhail, Dungan, Jan, Kuo, Alan, ...

Recent sequencing and assembly of the genome for the fungal pathogen Candida albicans used simple automated procedures for the identification of putative genes. We have reviewed the entire assembly,...

Identification of Essential Genes in the Human Fungal Pathogen Aspergillus fumigatus by Transposon Mutagenesis

Firon, Arnaud, Villalba, François, Beffa, Roland, D'Enfert, Christophe

The opportunistic pathogen Aspergillus fumigatus is the most frequent cause of deadly airborne fungal infections in developed countries. In order to identify novel antifungal-drug targets, we...

The Heterotrimeric G-Protein GanB(α)-SfaD(β)-GpgA(γ) Is a Carbon Source Sensor Involved in Early cAMP-Dependent Germination in Aspergillus nidulans

Lafon, Anne, Seo, Jeong-Ah, Han, Kap-Hoon, Yu, Jae-Hyuk, D'Enfert, Christophe

The role of heterotrimeric G-proteins in cAMP-dependent germination of conidia was investigated in the filamentous ascomycete Aspergillus nidulans. We demonstrate that the Gα-subunit GanB mediates a...

Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA.

Firon, Arnaud, Beauvais, Anne, Latgé, Jean-Paul, Couvé, Elisabeth, Grosjean-Cournoyer, Marie-Claire, D'Enfert, Christophe

We have evaluated the usefulness of parasexual genetics in the identification of genes essential for the growth of the human fungal pathogen Aspergillus fumigatus. First, essentiality of the A....

Identification of Essential Genes in the Human Fungal Pathogen Aspergillus fumigatus by Transposon Mutagenesis

Firon, Arnaud, Villalba, François, Beffa, Roland, D'Enfert, Christophe

The opportunistic pathogen Aspergillus fumigatus is the most frequent cause of deadly airborne fungal infections in developed countries. In order to identify novel antifungal-drug targets, we...

Candida albicans Biofilms: a Developmental State Associated With Specific and Stable Gene Expression Patterns

García-Sánchez, Susana, Aubert, Sylvie, Iraqui, Ismaïl, Janbon, Guilhem, Ghigo, Jean-Marc, D'Enfert, Christophe

Like many bacteria, yeast species can form biofilms on several surfaces. Candida albicans colonizes the surfaces of catheters, prostheses, and epithelia, forming biofilms that are extremely resistant...

A Human-Curated Annotation of the Candida albicans Genome

Braun, Burkhard R, Van Het Hoog, Marco, D'Enfert, Christophe, Martchenko, Mikhail, Dungan, Jan, Kuo, Alan, ...

Recent sequencing and assembly of the genome for the fungal pathogen Candida albicans used simple automated procedures for the identification of putative genes. We have reviewed the entire assembly,...

The Heterotrimeric G-Protein GanB(α)-SfaD(β)-GpgA(γ) Is a Carbon Source Sensor Involved in Early cAMP-Dependent Germination in Aspergillus nidulans

Lafon, Anne, Seo, Jeong-Ah, Han, Kap-Hoon, Yu, Jae-Hyuk, D'Enfert, Christophe

The role of heterotrimeric G-proteins in cAMP-dependent germination of conidia was investigated in the filamentous ascomycete Aspergillus nidulans. We demonstrate that the Gα-subunit GanB mediates a...

Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA.

Firon, Arnaud, Beauvais, Anne, Latgé, Jean-Paul, Couvé, Elisabeth, Grosjean-Cournoyer, Marie-Claire, D'Enfert, Christophe

We have evaluated the usefulness of parasexual genetics in the identification of genes essential for the growth of the human fungal pathogen Aspergillus fumigatus. First, essentiality of the A....

Molecular Phylogenetics of Candida albicans▿ †

Odds, Frank C., Bougnoux, Marie-Elisabeth, Shaw, Duncan J., Bain, Judith M., Davidson, Amanda D., Diogo, Dorothée, ...

We analyzed data on multilocus sequence typing (MLST), ABC typing, mating type-like locus (MAT) status, and antifungal susceptibility for a panel of 1,391 Candida albicans isolates. Almost all...

Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates▿ †

Coste, Alix, Selmecki, Anna, Forche, Anja, Diogo, Dorothée, Bougnoux, Marie-Elisabeth, D'Enfert, Christophe, ...

TAC1 (for transcriptional activator of CDR genes) is critical for the upregulation of the ABC transporters CDR1 and CDR2, which mediate azole resistance in Candida albicans. While a wild-type TAC1...

Multilocus Sequence Typing Reveals that the Population Structure of Candida dubliniensis Is Significantly Less Divergent than That of Candida albicans▿ †

McManus, Brenda A., Coleman, David C., Moran, Gary, Pinjon, Emmanuelle, Diogo, Dorothée, Bougnoux, Marie-Elisabeth, ...

The pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using...

The Yak1 Kinase Is Involved in the Initiation and Maintenance of Hyphal Growth in Candida albicans

Goyard, Sophie, Knechtle, Philipp, Chauvel, Murielle, Mallet, Adeline, Prévost, Marie-Christine, Proux, Caroline, ...

Members of the dual-specificity tyrosine-phosphorylated and regulated kinase (DYRK) family perform a variety of functions in eukaryotes. We used gene disruption, targeted pharmacologic inhibition,...