Christophe Hitte

Revisiting the missing protein-coding gene catalog of the domestic dog (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine A, Galibert, Francis, ...

Abstract Background Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000,...

Genetic diversity of canine olfactory receptors (2009)

Robin, Stéphanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dréano, Stéphane, André, Catherine, ...

Abstract Background Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Genetic diversity of canine olfactory receptors. (2009)

Robin, Stephanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dreano, Stephane, Andre, Catherine, ...

ABSTRACT: BACKGROUND: Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Genetic diversity of canine olfactory receptors. (2009)

Robin, Stephanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dreano, Stephane, Andre, Catherine, ...

ABSTRACT: BACKGROUND: Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Revisiting the missing protein-coding gene catalog of the domestic dog. (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine, Galibert, Francis, ...

BACKGROUND: Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000, compared to...

Revisiting the missing protein-coding gene catalog of the domestic dog. (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine, Galibert, Francis, ...

BACKGROUND: Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000, compared to...

Revisiting the missing protein-coding gene catalog of the domestic dog. (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine, Galibert, Francis, ...

BACKGROUND: Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000, compared to...

Genetic diversity of canine olfactory receptors. (2009)

Robin, Stephanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dreano, Stephane, Andre, Catherine, ...

ABSTRACT: BACKGROUND: Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Intrabreed Stratification Related to Divergent Selection Regimes in Purebred Dogs May Affect the Interpretation of Genetic Association Studies (2009)

Chang, Melanie L., Yokoyama, Jennifer S., Branson, Nick, Dyer, Donna J., Hitte, Christophe, Overall, Karen L., ...

Until recently, canine genetic research has not focused on population structure within breeds, which may confound the results of case–control studies by introducing spurious correlations between...

comparative genome (2008)

Thomas Derrien, Catherine André, Francis Galibert, Christophe Hitte, Alfonso Valencia

AutoGRAPH: an interactive web server for automating and visualizing

Survey sequencing and radiation hybrid mapping to construct comparative maps. (2008)

Hitte, Christophe, Kirkness, Ewen, Ostrander, Elaine A, Galibert, Francis

Radiation hybrid (RH) mapping has become one of the most well-established techniques for economically and efficiently navigating genomes of interest. The success of the technique relies on random...

Survey sequencing and radiation hybrid mapping to construct comparative maps. (2008)

Hitte, Christophe, Kirkness, Ewen, Ostrander, Elaine A, Galibert, Francis

Radiation hybrid (RH) mapping has become one of the most well-established techniques for economically and efficiently navigating genomes of interest. The success of the technique relies on random...

Analysis of the Unassembled Part of the Dog Genome Sequence: Chromosomal Localization of 115 Genes Inferred from Multispecies Comparative Genomics (2007)

Derrien, Thomas, André, Catherine, Galibert, Francis, Hitte, Christophe

The identification of dog genes and their accurate localization to chromosomes remain a major challenge in the postgenomics era. The 132 annotated canine genes with human orthologs remaining in the...

A comparative genome approach to marker ordering (2007)

Thomas Faraut, Simon De Givry, Patrick Chabrier, Thomas Derrien, Francis Galibert, Christophe Hitte, ...

∗ Both authors contributed equally to this work. Abstract: The increased number of genomes being sequenced offers new opportunities for the mapping of closely related organisms. We propose an...

AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps (2007)

Derrien, Thomas, André, Catherine, Galibert, Francis, Hitte, Christophe

AutoGRAPH is an interactive web server for automatic multi-species comparative genomics analyses based on personal datasets or pre-inserted public datasets. This program automatically identifies...

Coat colour in dogs: identification of the Merlelocus in the Australian shepherd breed (2006)

Hédan, Benoit, Corre, Sébastien, Hitte, Christophe, Dréano, Stéphane, Vilboux, Thierry, Derrien, Thomas, ...

Abstract Background Coat colours in canines have many natural phenotypic variants. Some of the genes and alleles involved also cause genetic developmental defects, which are also observed in humans...

BIOINFORMATICS APPLICATIONS NOTE (2006)

Genome Analysis, Thomas Derrien, Catherine André, Francis Galibert, Christophe Hitte

Vol. 23 no. 4 2007, pages 498–499 doi:10.1093/bioinformatics/btl618 AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors (2005)

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

An integrated 4249 marker FISH/RH map of the canine genome (2004)

Breen, Matthew, Hitte, Christophe, Lorentzen, Travis D, Thomas, Rachael, Cadieu, Edouard, Sabacan, Leah, ...

Abstract Background The 156 breeds of dog recognized by the American Kennel Club offer a unique opportunity to map genes important in genetic variation. Each breed features a defining constellation...

CRH_Server: an online comparative and radiation hybrid mapping server for the canine genome (2004)

Hitte, Christophe, Derrien, Thomas, André, Catherine, Ostrander, Elaine A., Galibert, Francis

Summary: CRH_Server is an on line Comparative and Radiation Hybrid mapping Server dedicated to canine genomics. CRH_Server allows users to compute their own RH data using the current canine RH map,...

CRH_server: an online comparative and radiation hybrid mapping server for the canine genome (2004)

Hitte, Christophe, Derrien, Thomas, André, Catherine, Ostrander, Elaine A., Galibert, Francis

Summary: CRH_Server is an on line Comparative and Radiation Hybrid mapping Server dedicated to canine genomics. CRH_Server allows users to compute their own RH data using the current canine RH map,...

CRH_server: an online comparative and radiation hybrid mapping server for the canine genome (2004)

Hitte, Christophe, Derrien, Thomas, André, Catherine, Ostrander, Elaine A., Galibert, Francis

Summary: CRH_Server is an on line Comparative and Radiation Hybrid mapping Server dedicated to canine genomics. CRH_Server allows users to compute their own RH data using the current canine RH map,...

Comparison of the canine and human olfactory receptor gene repertoires (2003)

Quignon, Pascale, Kirkness, Ewen, Cadieu, Edouard, Touleimat, Nizar, Guyon, Richard, Renier, Corinne, ...

Abstract Background Olfactory receptors (ORs), the first dedicated molecules with which odorants physically interact to arouse an olfactory sensation, constitute the largest gene family in...

A Mutation in the Canine BHD Gene is Associated with Hereditary Multifocal Renal Cystadenocarcinoma and Nodular Dermatofibrosis in the German Shepherd Dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A Mutation in the Canine BHD Gene is Associated with Hereditary Multifocal Renal Cystadenocarcinoma and Nodular Dermatofibrosis in the German Shepherd Dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A 1-Mb resolution radiation hybrid map of the canine genome

Guyon, Richard, Lorentzen, Travis D., Hitte, Christophe, Kim, Lisa, Cadieu, Edouard, Parker, Heidi G., ...

The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the...

Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes

Breen, Matthew, Jouquand, Sophie, Renier, Corinne, Mellersh, Cathryn S., Hitte, Christophe, Holmes, Nigel G., ...

We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of...

Comparison of the canine and human olfactory receptor gene repertoires

Quignon, Pascale, Kirkness, Ewen, Cadieu, Edouard, Touleimat, Nizar, Guyon, Richard, Renier, Corinne, ...

In this study, 817 novel canine olfactory receptor (OR) sequences were identified, and 640 have been characterized. Of the 661 characterized OR sequences, representing half of the canine repertoire,...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

A 1-Mb resolution radiation hybrid map of the canine genome

Guyon, Richard, Lorentzen, Travis D., Hitte, Christophe, Kim, Lisa, Cadieu, Edouard, Parker, Heidi G., ...

The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the...

Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes

Breen, Matthew, Jouquand, Sophie, Renier, Corinne, Mellersh, Cathryn S., Hitte, Christophe, Holmes, Nigel G., ...

We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of...

Comparison of the canine and human olfactory receptor gene repertoires

Quignon, Pascale, Kirkness, Ewen, Cadieu, Edouard, Touleimat, Nizar, Guyon, Richard, Renier, Corinne, ...

In this study, 817 novel canine olfactory receptor (OR) sequences were identified, and 640 have been characterized. Of the 661 characterized OR sequences, representing half of the canine repertoire,...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...