A New Test of the Statistical Nature of the Brightest Cluster Galaxies (2009)
Lin, Yen-Ting, Ostriker, Jeremiah P., Miller, Christopher J.
A novel statistic is proposed to examine the hypothesis that all cluster galaxies are drawn from the same luminosity distribution (LD). In such a "statistical model" of galaxy LD, the brightest...
Early assembly of the most massive galaxies (2009)
Collins, Chris A., Stott, John P., Hilton, Matt, Kay, Scott T., Stanford, S. Adam, Davidson, Michael, ...
The current consensus is that galaxies begin as small density fluctuations in the early Universe and grow by in situ star formation and hierarchical merging. Stars begin to form relatively quickly in...
Hilton, Matt, Stanford, S. Adam, Stott, John P., Collins, Chris A., Hoyle, Ben, Davidson, Michael, ...
We present a study of the morphological fractions and color-magnitude relation in the most distant X-ray selected galaxy cluster currently known, XMMXCS J2215.9-1738 at z=1.46, using a combination of...
Revealing components of the galaxy population through nonparametric techniques (2008)
Bamford, Steven P., Rojas, Alex L., Nichol, Robert C., Miller, Christopher J., Wasserman, Larry, Genovese, Christopher R., ...
The distributions of galaxy properties vary with environment, and are often multimodal, suggesting that the galaxy population may be a combination of multiple components. The behaviour of these...
Galaxy Zoo: the dependence of morphology and colour on environment (2008)
Bamford, Steven P., Nichol, Robert C., Baldry, Ivan K., Land, Kate, Lintott, Chris J., Schawinski, Kevin, ...
We analyse the relationships between galaxy morphology, colour, environment and stellar mass using data for over 100,000 objects from Galaxy Zoo, the largest sample of visually classified...
Testing the Utility of Self-report Screens to Detect Bipolar Disorder among Undergraduates (2008)
Background: Bipolar disorders represent a serious mental health problem, but clinicians often fail to detect bipolar diagnoses. The validation of brief and accurate self-report questionnaires may aid...
X-ray Observations of Optically Selected Giant Elliptical-Dominated Galaxy Groups (2008)
Voevodkin, Alexey, Miller, Christopher J., Borozdin, Konstantin, Heitmann, Katrin, Habib, Salman, Ricker, Paul, ...
We present a combined optical and X-ray analysis of three optically selected X-ray bright groups with giant elliptical galaxies in the center. These massive ellipticals were targeted for XMM-Newton...
Sahlén, Martin, Viana, Pedro T. P., Liddle, Andrew R., Romer, A. Kathy, Davidson, Michael, Sabirli, Kivanc, ...
We forecast the constraints on the values of sigma_8, Omega_m, and cluster scaling relation parameters which we expect to obtain from the XMM Cluster Survey (XCS). We assume a flat Lambda-CDM...
Mass and Redshift Dependence of Star Formation in Relaxed Galaxy Clusters (2008)
Finn, Rose A., Balogh, Michael L., Zaritsky, Dennis, Miller, Christopher J., Nichol, Robert C.
We investigate the star-formation properties of dynamically relaxed galaxy clusters as a function of cluster mass for 308 low-redshift clusters drawn from the Sloan Digital Sky Survey (SDSS) C4...
Brent Bryan, Robert C. Nichol, Christopher R. Genovese, Jeff Schneider, Christopher J. Miller, Observatorio Cerro Tololo, ...
We present an efficient algorithm to actively select queries for learning the boundaries separating a function domain into regions where the function is above and below a given threshold. We develop...
Brent Bryan, Robert C. Nichol, Christopher R. Genovese, Jeff Schneider, Christopher J. Miller, Observatorio Cerro Tololo, ...
We present an efficient algorithm to actively select queries for learning the boundaries separating a function domain into regions where the function is above and below a given threshold. We develop...
Active Learning For Identifying Function (2008)
Threshold Boundaries Brent, Brent Bryan, Robert C. Nichol, Christopher R. Genovese, Jeff Schneider, Christopher J. Miller, ...
We present an efficient algorithm to actively select queries for learning the boundaries separating a function domain into regions where the function is above and below a given threshold. We develop...
Active Learning For Identifying Function (2008)
Threshold Boundaries Brent, Brent Bryan, Robert C. Nichol, Christopher R. Genovese, Jeff Schneider, Christopher J. Miller, ...
We present an efficient algorithm to actively select queries for learning the boundaries separating a function domain into regions where the function is above and below a given threshold. We develop...
The XMM Cluster Survey: The Dynamical State of XMMXCS J2215.9-1738 at z=1.457 (2007)
Hilton, Matt, Collins, Chris A., Stanford, S. Adam, Lidman, Chris, Dawson, Kyle S., Davidson, Michael, ...
We present new spectroscopic observations of the most distant X-ray selected galaxy cluster currently known, XMMXCS J2215.9-1738 at z=1.457, obtained with the DEIMOS instrument at the W. M. Keck...
Mapping the Cosmological Confidence Ball Surface (2007)
Bryan, Brent, Schneider, Jeff, Miller, Christopher J., Nichol, Robert C., Genovese, Christopher, Wasserman, Larry
We present a new technique to compute simultaneously valid confidence intervals for a set of model parameters. We apply our method to the Wilkinson Microwave Anisotropy Probe's (WMAP) Cosmic...
Berlind, Andreas A., Frieman, Joshua A., Weinberg, David H., Blanton, Michael R., Warren, Michael S., Abazajian, Kevork, ...
We identify galaxy groups and clusters in volume-limited samples of the SDSS redshift survey, using a redshift-space friends-of-friends algorithm. We optimize the friends-of-friends linking lengths...
Statistical Computations with AstroGrid and the Grid (2005)
Nichol, Robert C, Smith, Garry, Miller, Christopher J, Genovese, Chris, Wasserman, Larry, Bryan, Brent, ...
We outline our first steps towards marrying two new and emerging technologies; the Virtual Observatory (e.g, AstroGrid) and the computational grid. We discuss the construction of VOTechBroker, which...
Cluster Merger Variance and the Luminosity Gap Statistic (2005)
Milosavljevic, Milos, Miller, Christopher J., Furlanetto, Steven R., Cooray, Asantha
The presence of multiple luminous galaxies in clusters can be explained by the finite time over which a galaxy sinks to the center of the cluster and merges with the the central galaxy. The simplest...
Schulte-Ladbeck, Regina E., K"onig, Brigitte, Miller, Christopher J., Hopkins, Andrew M., Drozdovsky, Igor O., Turnshek, David A., ...
We report HST/STIS spectroscopy and Gemini/GMOS-N imaging of the Damped Lyman Alpha (DLA) system toward HS 1543+5921 caused by the host star-forming galaxy (SFG) SBS 1543+593. The Gemini image shows...
The C4 Clustering Algorithm: Clusters of Galaxies in the Sloan Digital Sky Survey (2005)
Miller, Christopher J., Nichol, Robert, Reichart, Dan, Wechsler, Risa, Evrard, August, Annis, James, ...
We present the "C4 Cluster Catalog", a new sample of 748 clusters of galaxies identified in the spectroscopic sample of the Second Data Release (DR2) of the Sloan Digital Sky Survey (SDSS). The C4...
Star-forming galaxies in the sloan digital sky survey - the view from Pittsburgh (2005)
Schulte-Ladbeck, Regina E., Miller, Christopher J., Hopp, Ulrich, Hopkins, Andrew, Nichol, Robert C., Voges, Wolfgang, ...
The C4 clustering algorithm: clusters of galaxies in the sloan digital sky survey (2005)
Miller, Christopher J., Nichol, Robert C., Reichart, Daniel, Wechsler, Risa H., Evrard, August E., Annis, James, ...
The C4 clustering algorithm: Clusters of galaxies in the Sloan Digital Sky Survey (2005)
Miller, Christopher J., Nichol, Robert C., Reichart, Daniel, Wechsler, Risa H., Evrard, August E., Annis, James, ...
We present the C4 Cluster Catalog, a new sample of 748 clusters of galaxies identified in the spectroscopic sample of the Second Data Release (DR2) of the Sloan Digital Sky Survey (SDSS). The C4...
Immunodeficiency Virus Infection (2005)
Kristina Abel, David M. Rocke, Barinderpal Chohan, Linda Fritts, Christopher J. Miller
The current knowledge about early innate immune responses at mucosal sites of human immunodeficiency virus (HIV) entry is limited but likely to be important in the design of effective HIV vaccines...
Conditional Density Estimation using Finite Mixture Models with (2005)
An Application To, Alex L. Rojas, Christopher R. Genovese, Christopher J. Miller, Robert Nichol, Larry Wasserman
Conditional density estimation (CDE) is a statistical technique that allows for a better understanding of the relationship between a response variable and a set of covariates, in comparison with...
Nonparametric Inference for the Cosmic Microwave Background (2004)
Genovese, Christopher R., Miller, Christopher J., Nichol, Robert C., Arjunwadkar, Mihir, Wasserman, Larry
The Cosmic Microwave Background (CMB), which permeates the entire Universe, is the radiation left over from just 380,000 years after the Big Bang. On very large scales, the CMB radiation field is...
The Clustering of AGN in the Sloan Digital Sky Survey (2004)
Wake, David A., Miller, Christopher J., Di Matteo, Tiziana, Nichol, Robert C., Pope, Adrian, Szalay, Alexander S., ...
We present the two--point correlation function (2PCF) of narrow-line active galactic nuclei (AGN) selected within the First Data Release of the Sloan Digital Sky Survey. Using a sample of 13605 AGN...
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Nonparametric Inference for the Cosmic Microwave Background (2004)
Genovese, Christopher R., Miller, Christopher J., Nichol, Robert C., Arjunwadkar, Mihir, Wasserman, Larry
The cosmic microwave background (CMB), which permeates the entire Universe, is the radiation left over from just 380,000 years after the Big Bang. On very large scales, the CMB radiation field is...
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
The clustering of active galactic nuclei in the Sloan Digital Sky Survey (2004)
Wake, David A., Miller, Christopher J., Di Matteo, Tiziana, Nichol, Robert C., Pope, Adrian, Szalay, Alexander S., ...
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Galaxy ecology : groups and low-density environments in the SDSS and 2dFGRS (2004)
Balogh, Michael L., Eke, Vince, Miller, Christopher J., Lewis, Ian, Bower, Richard G., Couch, Warrick J., ...
We analyse the observed correlation between galaxy environment and Hα emission-line strength, using volume-limited samples and group catalogues of 24 968 galaxies at 0.05 < z < 0.095,...
The bimodal galaxy color distribution: dependence on luminosity and environment (2004)
Balogh, Michael L., Baldry, Ivan K., Nichol, Robert C., Miller, Christopher J., Bower, Richard G., Glazebrook, Karl
We analyze the u - r color distribution of 24,346 galaxies with M r ≤ -18 and z < 0.08, drawn from the Sloan Digital Sky Survey first data release, as a function of luminosity and...
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Galaxy ecology: groups and low-density environments in the SDSS and 2dFGRS (2004)
Balogh, Michael L., Eke, Vince, Miller, Christopher J., Lewis, Ian, Bower, Richard G., Couch, Warrick J., ...
We analyse the observed correlation between galaxy environment and Hα emission-line strength, using volume-limited samples and group catalogues of 24 968 galaxies at 0.05 < z < 0.095, drawn from the...
The bimodal galaxy color distribution: dependence on luminosity and environment (2004)
Balogh, Michael L., Baldry, Ivan K., Nichol, Robert C., Miller, Christopher J., Bower, Richard G., Glazebrook, Karl
We analyze the u - r color distribution of 24,346 galaxies with M r ≤ -18 and z < 0.08, drawn from the Sloan Digital Sky Survey first data release, as a function of luminosity and...
Miller, Christopher J., Packham, Gary A., Pickernell, David G., McGovern, Mark F.
Government aid offered to Wales, and largely spent on attracting foreign direct investment, has yet to provide tangible benefits in terms of relative economic prosperity and sustained job creation....
Star-Forming Galaxies in the Sloan Digital Sky Survey -- The View from Pittsburgh (2003)
Schulte-Ladbeck, Regina E., Miller, Christopher J., Hopp, Ulrich, Hopkins, Andrew, Nichol, Robert C., Voges, Wolfgang, ...
We used data from the Data Release 1 (DR1) of the Sloan Digital Sky Survey (SDSS) in order to define a catalog of about 13,000 star-forming galaxies (SFG). We discuss the results of two projects....
The Environment of AGNs in the Sloan Digital Sky Survey (2003)
Miller, Christopher J., Nichol, Robert C., Gomez, Percy, Hopkins, Andrew, Bernardi, Mariangela
We present the observed fraction of galaxies with an Active Galactic Nucleus (AGN) as a function of environment in the Early Data Release of the Sloan Digital Sky Survey (SDSS). Using 4921 galaxies...
The Morphological Butcher-Oemler effect in the SDSS Cut&Enhance Galaxy Cluster Catalog (2003)
Goto, Tomotsugu, Okamura, Sadanori, Yagi, Masafumi, Sheth, Ravi K., Bahcall, Neta A., Zabel, Shane A., ...
We investigate the evolution of the fractions of late type cluster galaxies as a function of redshift, using one of the largest, most uniform cluster samples available. The sample consists of 514...
The Environment of Passive Spiral Galaxies in the SDSS (2003)
Goto, Tomotsugu, Okamura, Sadanori, Sekiguchi, Maki, Bernardi, Mariangela, Brinkmann, Jon., Gomez, Percy L., ...
In previous work on galaxy clusters, several authors reported a discovery of an unusual population of galaxies, which have spiral morphologies, but do not show any star formation activity. These...
Hdelta-Selected Galaxies in the Sloan Digital Sky Survey I: The Catalog (2003)
Goto, Tomotsugu, Nichol, Robert C., Miller, Christopher J., Bernardi, Mariangela, Hopkins, Andrew, Tremonti, Christy, ...
[Abridged] We present here a new and homogeneous sample of 3340 galaxies selected from the Sloan Digital Sky Survey (SDSS) based solely on the observed strength of their Hdelta absorption line. These...
The Interplay of Cluster and Galaxy Evolution (2003)
Nichol, Robert C., Miller, Christopher J., Goto, Tomotsugu
We review here the interplay of cluster and galaxy evolution. As a case study, we consider the Butcher-Oemler effect and propose that it is the result of the changing rate of cluster merger events in...
Detecting the Baryons in Matter Power Spectra (2002)
Miller, Christopher J., Nichol, Robert C., Chen, Xuelei
We examine power spectra from the Abell/ACO rich cluster survey and the 2dF Galaxy Redshift Survey (2dfGRS) for observational evidence of features produced by the baryons. A non-negligible baryon...
A Non-parametric Analysis of the CMB Power Spectrum (2001)
Miller, Christopher J., Nichol, Robert C., Genovese, Christopher, Wasserman, Larry
We examine Cosmic Microwave Background (CMB) temperature power spectra from the BOOMERANG, MAXIMA, and DASI experiments. We non-parametrically estimate the true power spectrum with no model...
Non-Parametric Inference in Astrophysics (2001)
Wasserman, Larry, Miller, Christopher J., Nichol, Robert C., Genovese, Chris, Jang, Woncheol, Connolly, Andrew J., ...
We discuss non-parametric density estimation and regression for astrophysics problems. In particular, we show how to compute non-parametric confidence intervals for the location and size of peaks of...
Recent Dynamical Relaxation of Galaxy Clusters: Evidence for a Low-$\Omega_m$ Universe (2001)
Melott, Adrian L., Chambers, Scott W., Miller, Christopher J.
We argue that there has been substantial evolution in the ellipticity of rich galaxy clusters between 0 < z < 0.1, and suggest that this is additional evidence for a low matter-density Universe.
Controlling the False Discovery Rate in Astrophysical Data Analysis (2001)
Miller, Christopher J., Genovese, Christopher, Nichol, Robert C., Wasserman, Larry, Connolly, Andrew, Reichart, Daniel, ...
The False Discovery Rate (FDR) is a new statistical procedure to control the number of mistakes made when performing multiple hypothesis tests, i.e. when comparing many data against a given model...
Acoustic Oscillations in the Early Universe and Today (2001)
Miller, Christopher J., Nichol, Robert C., Batuski, David J.
During its first ~100,000 years, the universe was a fully ionized plasma with a tight coupling by Thompson scattering between the photons and matter. The trade--off between gravitational collapse and...
Possible Detection of Baryonic Fluctuations in the Large-Scale Structure Power Spectrum (2001)
Miller, Christopher J., Nichol, Robert C., Batuski, David J.
We present a joint analysis of the power spectra of density fluctuations from three independent cosmological redshift surveys; the PSCz galaxy catalog, the APM galaxy cluster catalog and the...
The Nearest Neighbor Alignment of Cluster X-ray Isophotes (2001)
Chambers, Scott W., Melott, Adrian L., Miller, Christopher J.
We examine the orientations of rich galaxy cluster X-ray isophotes with respect to their rich nearest neighbors using existing samples of Abell cluster position angles measured from {\it Einstein}...
Einstein Cluster Alignments Revisited (2000)
Chambers, Scott W., Melott, Adrian L., Miller, Christopher J.
We have examined whether the major axes of rich galaxy clusters tend to point toward their nearest neighboring cluster. We have used the data of Ulmer, McMillan, and Kowalski, who used position...
The Power Spectrum of Rich Clusters on Near Gigaparsec Scales (2000)
Miller, Christopher J., Batuski, David J.
Recently, there have been numerous analyses of the redshift space power spectrum of rich clusters of galaxies. Some of these analyses indicate a "bump" in the Abell/ACO cluster power spectrum around...
Wavelength Doesn't Matter: Optical vs. X-ray Luminosities of Galaxy Clusters (1999)
Miller, Christopher J., Melott, Adrian L., Nichol, Robert C.
We examine the relationship between the total X-ray and optical luminosities of groups and clusters of galaxies taken from various samples in the literature. The clusters and groups were drawn from...
Environmental Dependence of the Fundamental Plane of Galaxy Clusters (1999)
Miller, Christopher J., Melott, Adrian, Gorman, Patrick
Galaxy clusters approximate a planar (FP) distribution in a three-dimensional parameter space which can be characterized by optical luminosity, half-light radius, and X-ray luminosity. Using a...
Massive Cooling Flow Clusters Inhabit Crowded Environments (1999)
Loken, Chris, Melott, Adrian L., Miller, Christopher J.
With the availability of large-scale redshift survey data, it is now becoming possible to explore correlations between large-scale structure and the properties and morphologies of galaxy clusters. We...
Thesis (M.A.)--Northern Illinois University, 1999.
Typescript.
Developmental Toxicity of L-Selenomethionine in Macaca fascicularis (1991)
TARANTAL, ALICE F., WILLHITE, CALVIN C., LASLEY, BILL L., MURPHY, CHRISTOPHER J., MILLER, CHRISTOPHER J., CUKIERSKI, MATTHEW J., ...
Forty pregnant long-tailed macaques were dosed via nasogastric intubation with 0, 25, 150, or 300 μg/kg of L-selenomethionine (Se) daily during organogenesis [Gestational Day (GD) 20–50]....
Miller, Christopher J. (Christopher John)
Binder's title: Cleveland medical thesis, 1863-1864, v. 27.
Wyand, Michael S., Manson, Kelledy H., Miller, Christopher J., Neurath, A. Robert
Heterosexual transmission of human immunodeficiency virus type 1 (HIV-1) is the major cause of the ongoing AIDS epidemic. Application of chemical barrier methods is expected to contribute to the...
Tang, Yi-Quan, Yuan, Jun, Miller, Christopher J., Selsted, Michael E.
Experiments to isolate and characterize rhesus macaque myeloid α-defensins (RMADs) were conducted. Seven RMAD peptides were isolated and sequenced, and the cDNAs encoding six of these peptides and...
Lü, F. Xusheng, Ma, Zhongmin, Rourke, Tracy, Srinivasan, Seema, McChesney, Michael, Miller, Christopher J.
The levels of antigen-specific antibodies (Abs) and immunoglobulins in the cervical mucus of women vary with the menstrual cycle; the highest levels occur during menses, and the lowest occur during...
Buge, Suzan L., Murty, Lalita, Arora, Kamalpreet, Kalyanaraman, V. S., Markham, Phillip D., Richardson, Ersell S., ...
Rhesus macaques were immunized with a combination vaccine regimen consisting of adenovirus type 5 host range mutant-simian immunodeficiency virus envelope (Ad5hr-SIVenv) recombinant priming and...
Miller, Christopher J., Marthas, Marta, Greenier, Jennifer, Lu, Ding, Dailey, Peter J., Lu, Yichen
We used the rhesus macaque model of heterosexual human immunodeficiency virus (HIV) transmission to test the hypothesis that in vitro measures of macrophage tropism predict the ability of a primate...
McChesney, Michael B., Collins, Jennifer R., Lu, Ding, Lu, Xusheng, Torten, Judith, Ashley, Rhoda L., ...
The intact cervicovaginal mucosa is a relative barrier to the sexual transmission of human immunodeficiency virus type 1 (HIV-1). In the simian immunodeficiency virus (SIV) macaque model of HIV...
Hu, Jinjie, Gardner, Murray B., Miller, Christopher J.
Despite recent insights into mucosal human immunodeficiency virus (HIV) transmission, the route used by primate lentiviruses to traverse the stratified squamous epithelium of mucosal surfaces remains...
Himathongkham, Sunee, Halpin, Nancy S., Li, Jinling, Stout, Michael W., Miller, Christopher J., Luciw, Paul A.
The envelope (env) glycoprotein of human immunodeficiency virus type 1 (HIV-1) determines several viral properties (e.g., coreceptor usage, cell tropism, and cytopathicity) and is a major target of...
Crotty, Shane, Lohman, Barbara L., Lü, Fabien X.-S., Tang, ShenBei, Miller, Christopher J., Andino, Raul
Poliovirus live virus vectors are a candidate recombinant vaccine system. Previous studies using this system showed that a live poliovirus vector expressing a foreign antigen between the structural...
Buge, Suzan L., Murty, Lalita, Arora, Kamalpreet, Kalyanaraman, V. S., Markham, Phillip D., Richardson, Ersell S., ...
Greenier, Jennifer L., Miller, Christopher J., Lu, Ding, Dailey, Peter J., Lü, Fabien X., Kunstman, Kevin J., ...
A better understanding of the host and viral factors associated with human immunodeficiency virus (HIV) transmission is essential to developing effective strategies to curb the global HIV epidemic....
Protection against Simian Immunodeficiency Virus Vaginal Challenge by Using Sabin Poliovirus Vectors
Crotty, Shane, Miller, Christopher J., Lohman, Barbara L., Neagu, Martha R., Compton, Lara, Lu, Ding, ...
Here we provide the first report of protection against a vaginal challenge with a highly virulent simian immunodeficiency virus (SIV) by using a vaccine vector. New poliovirus vectors based on Sabin...
Makori, Norbert, Tarantal, Alice F., Lü, Fabien X., Rourke, Tracy, Marthas, Marta L., McChesney, Michael B., ...
Little is known regarding the timing of immune ontogeny and effector function in fetal humans and nonhuman primates. We studied the organization of lymphocyte and antigen-presenting cell populations...
Abel, Kristina, Compton, Lara, Rourke, Tracy, Montefiori, David, Lu, Ding, Rothaeusler, Kristina, ...
Attenuated primate lentivirus vaccines provide the most consistent protection against challenge with pathogenic simian immunodeficiency virus (SIV). Thus, they provide an excellent model to examine...
Effects of Ovarian Steroids on Immunoglobulin-Secreting Cell Function in Healthy Women
Lü, Fabien X., Ma, Zhongmin, Moser, Susie, Evans, Thomas G., Miller, Christopher J.
To determine the effect of the ovarian hormone cycle on immunity, immunoglobulin-secreting cell (ISC) frequency and lymphocyte subsets were examined in the blood of healthy women. We found that...
Abel, Kristina, Rourke, Tracy, Ma, Zhong-Min, De Silva, Veronique, Fallert, Beth, ...
Although gamma interferon (IFN-γ) is a key mediator of antiviral defenses, it is also a mediator of inflammation. As inflammation can drive lentiviral replication, we sought to determine the...
LaFranco-Scheuch, Lisa, Abel, Kristina, Makori, Norbert, Rothaeusler, Kristina, Miller, Christopher J.
Viral suppression by noncytolytic CD8+ T cells, in addition to that by classic antiviral CD8+ cytotoxic T lymphocytes, has been described for human immunodeficiency virus and simian immunodeficiency...
Ma, Zhong-Min, Abel, Kristina, Rourke, Tracy, Wang, Yichuan, Miller, Christopher J.
In rhesus macaques, classic systemic infection, characterized by persistent viremia and seroconversion, occurred after multiple low-dose (103 50% tissue culture infective doses) intravaginal (IVAG)...
Characterization of Virus-Responsive Plasmacytoid Dendritic Cells in the Rhesus Macaque
Chung, Eugene, Amrute, Sheela B., Abel, Kristina, Gupta, Gunjan, Wang, Yichuan, Miller, Christopher J., ...
Plasmacytoid dendritic cells (PDC) are potent producers of alpha interferon (IFN-α) in response to enveloped viruses and provide a critical link between the innate and adaptive immune responses....
Kim, Eun-Young, Busch, Marc, Abel, Kristina, Fritts, Linda, Bustamante, Patty, Stanton, Jenny, ...
To characterize the occurrence, frequency, and kinetics of retroviral recombination in vivo, we intravaginally inoculated rhesus macaques, either simultaneously or sequentially, with attenuated...
Abel, Kristina, Wang, Yichuan, Fritts, Linda, Sanchez, Eleonora, Chung, Eugene, Fitzgerald-Bocarsly, Patricia, ...
To determine if deoxycytidyl-deoxyguanosine oligonucleotides (CpG ODN) can be used effectively as nonspecific inducers of innate immune defenses for preventative or therapeutic interventions in...
Miller, Christopher J., Li, Qingsheng, Abel, Kristina, Kim, Eun-Young, Ma, Zhong-Min, Wietgrefe, Stephen, ...
Abel, Kristina, Rocke, David M., Chohan, Barinderpal, Fritts, Linda, Miller, Christopher J.
The current knowledge about early innate immune responses at mucosal sites of human immunodeficiency virus (HIV) entry is limited but likely to be important in the design of effective HIV vaccines...
Wang, Yichuan, Abel, Kristina, Lantz, Katherine, Krieg, Arthur M., McChesney, Michael B., Miller, Christopher J.
The initial host response to viral infection occurs after Toll-like receptors (TLRs) on dendritic cells (DC) are stimulated by viral nucleic acids (double-stranded RNA, single-stranded RNA) and alpha...
Abel, Kristina, Alegria-Hartman, Michelle J., Rothaeusler, Kristina, Marthas, Marta, Miller, Christopher J.
To define the role of alpha/beta interferons (IFN-α/β) in simian immunodeficiency virus (SIV) infection, IFN-α and IFN-β mRNA levels and mRNA levels of Mx, an antiviral effector molecule, were...
Miller, Christopher J., Li, Qingsheng, Abel, Kristina, Kim, Eun-Young, Ma, Zhong-Min, Wietgrefe, Stephen, ...
In the current global AIDS pandemic, more than half of new human immunodeficiency virus type 1 (HIV-1) infections are acquired by women through intravaginal HIV exposure. For this study, we explored...
Reynolds, Matthew R., Rakasz, Eva, Skinner, Pamela J., White, Cara, Abel, Kristina, Ma, Zhong-Min, ...
In the acute stage of infection following sexual transmission of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV), virus-specific CD8+ T-lymphocyte responses partially...
Quigley, Máire F., Abel, Kristina, Zuber, Bartek, Miller, Christopher J., Sandberg, Johan K., Shacklett, Barbara L.
Perforin-mediated cytotoxicity is a major effector function of virus-specific CD8 T cells. We have investigated the expression of perforin in the gut, an important site of simian immunodeficiency...
Wyand, Michael S., Manson, Kelledy H., Miller, Christopher J., Neurath, A. Robert
Heterosexual transmission of human immunodeficiency virus type 1 (HIV-1) is the major cause of the ongoing AIDS epidemic. Application of chemical barrier methods is expected to contribute to the...
Tang, Yi-Quan, Yuan, Jun, Miller, Christopher J., Selsted, Michael E.
Experiments to isolate and characterize rhesus macaque myeloid α-defensins (RMADs) were conducted. Seven RMAD peptides were isolated and sequenced, and the cDNAs encoding six of these peptides and...
Lü, F. Xusheng, Ma, Zhongmin, Rourke, Tracy, Srinivasan, Seema, McChesney, Michael, Miller, Christopher J.
The levels of antigen-specific antibodies (Abs) and immunoglobulins in the cervical mucus of women vary with the menstrual cycle; the highest levels occur during menses, and the lowest occur during...
Buge, Suzan L., Murty, Lalita, Arora, Kamalpreet, Kalyanaraman, V. S., Markham, Phillip D., Richardson, Ersell S., ...
Rhesus macaques were immunized with a combination vaccine regimen consisting of adenovirus type 5 host range mutant-simian immunodeficiency virus envelope (Ad5hr-SIVenv) recombinant priming and...
Miller, Christopher J., Marthas, Marta, Greenier, Jennifer, Lu, Ding, Dailey, Peter J., Lu, Yichen
We used the rhesus macaque model of heterosexual human immunodeficiency virus (HIV) transmission to test the hypothesis that in vitro measures of macrophage tropism predict the ability of a primate...
McChesney, Michael B., Collins, Jennifer R., Lu, Ding, Lu, Xusheng, Torten, Judith, Ashley, Rhoda L., ...
The intact cervicovaginal mucosa is a relative barrier to the sexual transmission of human immunodeficiency virus type 1 (HIV-1). In the simian immunodeficiency virus (SIV) macaque model of HIV...
Hu, Jinjie, Gardner, Murray B., Miller, Christopher J.
Despite recent insights into mucosal human immunodeficiency virus (HIV) transmission, the route used by primate lentiviruses to traverse the stratified squamous epithelium of mucosal surfaces remains...
Himathongkham, Sunee, Halpin, Nancy S., Li, Jinling, Stout, Michael W., Miller, Christopher J., Luciw, Paul A.
The envelope (env) glycoprotein of human immunodeficiency virus type 1 (HIV-1) determines several viral properties (e.g., coreceptor usage, cell tropism, and cytopathicity) and is a major target of...
Crotty, Shane, Lohman, Barbara L., Lü, Fabien X.-S., Tang, ShenBei, Miller, Christopher J., Andino, Raul
Poliovirus live virus vectors are a candidate recombinant vaccine system. Previous studies using this system showed that a live poliovirus vector expressing a foreign antigen between the structural...
Buge, Suzan L., Murty, Lalita, Arora, Kamalpreet, Kalyanaraman, V. S., Markham, Phillip D., Richardson, Ersell S., ...
Greenier, Jennifer L., Miller, Christopher J., Lu, Ding, Dailey, Peter J., Lü, Fabien X., Kunstman, Kevin J., ...
A better understanding of the host and viral factors associated with human immunodeficiency virus (HIV) transmission is essential to developing effective strategies to curb the global HIV epidemic....
Protection against Simian Immunodeficiency Virus Vaginal Challenge by Using Sabin Poliovirus Vectors
Crotty, Shane, Miller, Christopher J., Lohman, Barbara L., Neagu, Martha R., Compton, Lara, Lu, Ding, ...
Here we provide the first report of protection against a vaginal challenge with a highly virulent simian immunodeficiency virus (SIV) by using a vaccine vector. New poliovirus vectors based on Sabin...
Makori, Norbert, Tarantal, Alice F., Lü, Fabien X., Rourke, Tracy, Marthas, Marta L., McChesney, Michael B., ...
Little is known regarding the timing of immune ontogeny and effector function in fetal humans and nonhuman primates. We studied the organization of lymphocyte and antigen-presenting cell populations...
Abel, Kristina, Compton, Lara, Rourke, Tracy, Montefiori, David, Lu, Ding, Rothaeusler, Kristina, ...
Attenuated primate lentivirus vaccines provide the most consistent protection against challenge with pathogenic simian immunodeficiency virus (SIV). Thus, they provide an excellent model to examine...
Abel, Kristina, Alegria-Hartman, Michelle J., Rothaeusler, Kristina, Marthas, Marta, Miller, Christopher J.
To define the role of alpha/beta interferons (IFN-α/β) in simian immunodeficiency virus (SIV) infection, IFN-α and IFN-β mRNA levels and mRNA levels of Mx, an antiviral effector molecule, were...
Effects of Ovarian Steroids on Immunoglobulin-Secreting Cell Function in Healthy Women
Lü, Fabien X., Ma, Zhongmin, Moser, Susie, Evans, Thomas G., Miller, Christopher J.
To determine the effect of the ovarian hormone cycle on immunity, immunoglobulin-secreting cell (ISC) frequency and lymphocyte subsets were examined in the blood of healthy women. We found that...
Abel, Kristina, Rourke, Tracy, Ma, Zhong-Min, De Silva, Veronique, Fallert, Beth, ...
Although gamma interferon (IFN-γ) is a key mediator of antiviral defenses, it is also a mediator of inflammation. As inflammation can drive lentiviral replication, we sought to determine the...
LaFranco-Scheuch, Lisa, Abel, Kristina, Makori, Norbert, Rothaeusler, Kristina, Miller, Christopher J.
Viral suppression by noncytolytic CD8+ T cells, in addition to that by classic antiviral CD8+ cytotoxic T lymphocytes, has been described for human immunodeficiency virus and simian immunodeficiency...
Ma, Zhong-Min, Abel, Kristina, Rourke, Tracy, Wang, Yichuan, Miller, Christopher J.
In rhesus macaques, classic systemic infection, characterized by persistent viremia and seroconversion, occurred after multiple low-dose (103 50% tissue culture infective doses) intravaginal (IVAG)...
Characterization of Virus-Responsive Plasmacytoid Dendritic Cells in the Rhesus Macaque
Chung, Eugene, Amrute, Sheela B., Abel, Kristina, Gupta, Gunjan, Wang, Yichuan, Miller, Christopher J., ...
Plasmacytoid dendritic cells (PDC) are potent producers of alpha interferon (IFN-α) in response to enveloped viruses and provide a critical link between the innate and adaptive immune responses....
Kim, Eun-Young, Busch, Marc, Abel, Kristina, Fritts, Linda, Bustamante, Patty, Stanton, Jenny, ...
To characterize the occurrence, frequency, and kinetics of retroviral recombination in vivo, we intravaginally inoculated rhesus macaques, either simultaneously or sequentially, with attenuated...
Abel, Kristina, Wang, Yichuan, Fritts, Linda, Sanchez, Eleonora, Chung, Eugene, Fitzgerald-Bocarsly, Patricia, ...
To determine if deoxycytidyl-deoxyguanosine oligonucleotides (CpG ODN) can be used effectively as nonspecific inducers of innate immune defenses for preventative or therapeutic interventions in...
Miller, Christopher J., Li, Qingsheng, Abel, Kristina, Kim, Eun-Young, Ma, Zhong-Min, Wietgrefe, Stephen, ...
In the current global AIDS pandemic, more than half of new human immunodeficiency virus type 1 (HIV-1) infections are acquired by women through intravaginal HIV exposure. For this study, we explored...
Reynolds, Matthew R., Rakasz, Eva, Skinner, Pamela J., White, Cara, Abel, Kristina, Ma, Zhong-Min, ...
In the acute stage of infection following sexual transmission of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV), virus-specific CD8+ T-lymphocyte responses partially...
Miller, Christopher J., Li, Qingsheng, Abel, Kristina, Kim, Eun-Young, Ma, Zhong-Min, Wietgrefe, Stephen, ...
Abel, Kristina, Rocke, David M., Chohan, Barinderpal, Fritts, Linda, Miller, Christopher J.
The current knowledge about early innate immune responses at mucosal sites of human immunodeficiency virus (HIV) entry is limited but likely to be important in the design of effective HIV vaccines...
Wang, Yichuan, Abel, Kristina, Lantz, Katherine, Krieg, Arthur M., McChesney, Michael B., Miller, Christopher J.
The initial host response to viral infection occurs after Toll-like receptors (TLRs) on dendritic cells (DC) are stimulated by viral nucleic acids (double-stranded RNA, single-stranded RNA) and alpha...
Quigley, Máire F., Abel, Kristina, Zuber, Bartek, Miller, Christopher J., Sandberg, Johan K., Shacklett, Barbara L.
Perforin-mediated cytotoxicity is a major effector function of virus-specific CD8 T cells. We have investigated the expression of perforin in the gut, an important site of simian immunodeficiency...
Wang, Yichuan, Abel, Kristina, Lantz, Katherine, Krieg, Arthur M., McChesney, Michael B., Miller, Christopher J.
Antiviral Antibodies Are Necessary for Control of Simian Immunodeficiency Virus Replication▿
Miller, Christopher J., Genescà, Meritxell, Abel, Kristina, Montefiori, David, Forthal, Donald, Bost, Kristen, ...
To better define the role of B cells in the control of pathogenic simian immunodeficiency virus (SIV) replication, six rhesus monkeys were depleted of B cells by intravenous infusion of rituximab...
Michael A. Spencer, Stephen K. Swallow, Christopher J. Miller
This paper studies the preferences and willingness-to-pay of individuals for volunteer water quality monitoring programs. The study involves supporting water quality monitoring at two ponds in the...
Robert J. Johnston, Elena Y. Besedin, Richard Iovanna, Christopher J. Miller, Ryan F. Wardwell, Matthew H. Ranson
"Researchers are increasingly considering benefit transfer approaches that allow welfare measures to be adjusted for characteristics of the policy context. The validity and reliability of such...
Ambrose, Zandrea, Compton, Lara, Piatak, Michael, Lu, Ding, Alvord, W. Gregory, Lubomirski, Mariusz S., ...
The rising prevalence of human immunodeficiency virus type 1 (HIV-1) infection in women, especially in resource-limited settings, accentuates the need for accessible, inexpensive, and...
Hong, Jung Joo, Reynolds, Matthew R., Mattila, Teresa L., Hage, Aaron, Watkins, David I., Miller, Christopher J., ...
CD8 T cells play an important role in controlling viral infections. We investigated the in situ localization of simian immunodeficiency virus (SIV)-specific T cells in lymph and genital tissues from...
Spencer, Michael A., Swallow, Stephen K., Miller, Christopher J.
This paper studies the preferences and willingness-to-pay for individuals for volunteer water quality monitoring programs. The study involves supporting water quality monitoring at two ponds in the...
Favre, David, Lederer, Sharon, Kanwar, Bittoo, Ma, Zhong-Min, Proll, Sean, Kasakow, Zeljka, ...
Chronic immune activation and progression to AIDS are observed after SIV infection in macaques but not in natural host primate species. To better understand this dichotomy, we compared acute...
Genescà, Meritxell, Skinner, Pamela J., Hong, Jung Joo, Li, Jun, Lu, Ding, McChesney, Michael B., ...
The presence, at the time of challenge, of antiviral effector T cells in the vaginal mucosa of female rhesus macaques immunized with live-attenuated simian-human immunodeficiency virus 89.6...
Toxic Algae Contamination and Demand for Shellfish: A Case Study of Demand for Mussels in Montreal
Roheim Wessells, Cathy, Miller, Christopher J., Brooks, Priscilla M.
Toxic algae blooms are a worldwide phenomena, which appear to be increasing in frequency and severity. These natural events cause product contaminations that often have significant economic...
Lozano Reina, José-Manuel, Favre, David, Kasakow, Zeljka, Mayau, Véronique, Nugeyre, Marie-Thérèse, Ka, Thierno, ...
Nonpathogenic simian immunodeficiency virus SIVagm infection of African green monkeys (AGMs) is characterized by the absence of a robust antibody response against Gag p27. To determine if this is...
Ma, Zhong-Min, Stone, Mars, Piatak, Mike, Schweighardt, Becky, Haigwood, Nancy L., Montefiori, David, ...
To define the ratio of simian immunodeficiency virus (SIV) RNA molecules to infectious virions in plasma, a ramp-up-stage plasma pool was made from the earliest viral RNA (vRNA)-positive plasma...
Wang, Yichuan, Blozis, Shelley A., Lederman, Michael, Krieg, Arthur, Landay, Alan, Miller, Christopher J.
The potential benefit of using unmethylated CpG oligoribodeoxynucleotides (ODN) as an adjuvant in a therapeutic simian immunodeficiency virus (SIV) vaccine consisting of AT2-inactivated SIVmac239 was...