Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
Rothermel, Beverly A., McKinsey, Timothy A., Vega, Rick B., Nicol, Rebekka L., Mammen, Pradeep, Yang, John, ...
Signaling events controlled by calcineurin promote cardiac hypertrophy, but the degree to which such pathways are required to transduce the effects of various hypertrophic stimuli remains uncertain....
Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo
Antos, Christopher L., McKinsey, Timothy A., Frey, Norbert, Kutschke, William, McAnally, John, Shelton, John M., ...
The adult myocardium responds to a variety of pathologic stimuli by hypertrophic growth that frequently progresses to heart failure. The calcium/calmodulin-dependent protein phosphatase calcineurin...
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression
López-Rodríguez, Cristina, Antos, Christopher L., Shelton, John M., Richardson, James A., Lin, Fangming, Novobrantseva, Tatiana I., ...
The transcription factor NFAT5/TonEBP, a member of the NFAT/Rel family of transcription factors, has been implicated in diverse cellular responses, including the response to osmotic stress,...
Juhaszova, Magdalena, Zorov, Dmitry B., Kim, Suhn-Hee, Pepe, Salvatore, Fu, Qin, Fishbein, Kenneth W., ...
Environmental stresses converge on the mitochondria that can trigger or inhibit cell death. Excitable, postmitotic cells, in response to sublethal noxious stress, engage mechanisms that afford...
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
Rothermel, Beverly A., McKinsey, Timothy A., Vega, Rick B., Nicol, Rebekka L., Mammen, Pradeep, Yang, John, ...
Signaling events controlled by calcineurin promote cardiac hypertrophy, but the degree to which such pathways are required to transduce the effects of various hypertrophic stimuli remains uncertain....
Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo
Antos, Christopher L., McKinsey, Timothy A., Frey, Norbert, Kutschke, William, McAnally, John, Shelton, John M., ...
The adult myocardium responds to a variety of pathologic stimuli by hypertrophic growth that frequently progresses to heart failure. The calcium/calmodulin-dependent protein phosphatase calcineurin...
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression
López-Rodríguez, Cristina, Antos, Christopher L., Shelton, John M., Richardson, James A., Lin, Fangming, Novobrantseva, Tatiana I., ...
The transcription factor NFAT5/TonEBP, a member of the NFAT/Rel family of transcription factors, has been implicated in diverse cellular responses, including the response to osmotic stress,...
Juhaszova, Magdalena, Zorov, Dmitry B., Kim, Suhn-Hee, Pepe, Salvatore, Fu, Qin, Fishbein, Kenneth W., ...
Environmental stresses converge on the mitochondria that can trigger or inhibit cell death. Excitable, postmitotic cells, in response to sublethal noxious stress, engage mechanisms that afford...