Chuan-Ming Hao

Plasminogen activator inhibitor-1 modulates adipocyte differentiation (2006)

Kanjanabuch, Talerngsak, Mao, Su-Li, Hao, Chuan-Ming, Tang, Yi-Wei, ...

Increased plasminogen activator inhibitor-1 (PAI-1) is linked to obesity and insulin resistance. However, the functional role of PAI-1 in adipocytes is unknown. This study was designed to investigate...

Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., ...

Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present...

Dehydration activates an NF-κB–driven, COX2-dependent survival mechanism in renal medullary interstitial cells

Hao, Chuan-Ming, Yull, Fiona, Blackwell, Timothy, Kömhoff, Martin, Davis, Linda S., Breyer, Matthew D.

Renal prostaglandin (PG) synthesis is mediated by cyclooxygenase-1 and -2 (COX1 and COX2). After dehydration, the maintenance of normal renal function becomes particularly dependent upon PG...

Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., ...

Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present...

Dehydration activates an NF-κB–driven, COX2-dependent survival mechanism in renal medullary interstitial cells

Hao, Chuan-Ming, Yull, Fiona, Blackwell, Timothy, Kömhoff, Martin, Davis, Linda S., Breyer, Matthew D.

Renal prostaglandin (PG) synthesis is mediated by cyclooxygenase-1 and -2 (COX1 and COX2). After dehydration, the maintenance of normal renal function becomes particularly dependent upon PG...

Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor

Chen, Jian, Zhao, Min, He, Wenjuan, Milne, Ginger L., Howard, Jocelyn R. H., Morrow, Jason, ...

A high-NaCl diet induces renal medullary cyclooxygenase (COX)2 expression, and selective intramedullary infusion of a COX2 inhibitor increases blood pressure in rats on a high-salt diet. The present...

Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c

Han, Byoung Geun, Hao, Chuan-Ming, Tchekneva, Elena E., Wang, Ying-Ying, Lee, Chieh Allen, Ebrahim, Benyamin, ...

The present studies examined the relationship between fasting blood glucose and Hb A1c in C57BL/6J, DBA/2J, and KK/HlJ mice with and without diabetes mellitus. Daily averaged blood glucose levels...