Chun Liang

Role Of Fip200 In Cerebellar Degeneration (2009)

Liang, Chun

Although the primary function of autophagy is the supply of amino acids as a response to starvation conditions in many organisms, recent studies suggested that basal autophagy, which occurs...

WebGMAP: a web service for mapping and aligning cDNA sequences to genomes (2009)

Liang, Chun, Liu, Lin, Ji, Guoli

The genomes of thousands of organisms are being sequenced, often with accompanying sequences of cDNAs or ESTs. One of the great challenges in bioinformatics is to make these genomic sequences and...

mRNA expression of the DNA replication-initiation proteins in epithelial dysplasia and squamous cell carcinoma of the tongue (2008)

Li, Jian-na, Feng, Chong-jin, Lu, Yong-jun, Li, Hui-jun, Tu, Zheng, Liao, Gui-qing, ...

Abstract Background The tongue squamous cell carcinomas (SCCs) are characterized by high mitotic activity, and early detection is desirable. Overexpression of the DNA replication-initiation proteins...

Antisense oligonucleotides targeted to human cdc45 (2008)

Liang, Chun, Feng, Dao-rong, Yu, Zhiling

Antisense oligonucleotides that inhibit expression of human replication-initiation protein as well as methods of preventing or treating hyperproliferative conditions using said oligonucleotides are...

Sorghum Expressed Sequence Tags Identify Signature Genes for Drought, Pathogenesis, and Skotomorphogenesis from a Milestone Set of 16,801 Unique Transcripts 1[w] (2008)

Lee H. Pratt, Chun Liang, Manish Shah, Feng Sun, Haiming Wang, St. Patrick Reid, ...

This article is published in Plant Physiology Online, Plant Physiology Preview Section, which publishes manuscripts accepted for publication after they have been edited and the authors have corrected...

WebTraceMiner: a web service for processing and mining EST sequence trace files (2007)

Liang, Chun, Wang, Gang, Liu, Lin, Ji, Guoli, Liu, Yuansheng, Chen, Jinqiao, ...

Expressed sequence tags (ESTs) remain a dominant approach for characterizing the protein-encoding portions of various genomes. Due to inherent deficiencies, they also present serious challenges for...

ConiferEST: an integrated bioinformatics system for data reprocessing and mining of conifer expressed sequence tags (ESTs) (2007)

Liang, Chun, Wang, Gang, Liu, Lin, Ji, Guoli, Fang, Lin, Liu, Yuansheng, ...

Abstract Background With the advent of low-cost, high-throughput sequencing, the amount of public domain Expressed Sequence Tag (EST) sequence data available for both model and non-model organism is...

MAGIC-SPP: a database-driven DNA sequence processing package with associated management tools (2006)

Liang, Chun, Sun, Feng, Wang, Haiming, Qu, Junfeng, Freeman, Robert M, Pratt, Lee H, ...

Abstract Background Processing raw DNA sequence data is an especially challenging task for relatively small laboratories and core facilities that produce as many as 5000 or more DNA sequences per...

MAGIC Database and Interfaces: An Integrated Package for Gene Discovery and Expression (2006)

Chun Liang, Haiming Wang, Dmitri S. Kolychev, Feng Sun, Robert Freeman, ...

The rapidly increasing rate at which biological data is being produced requires a corresponding growth in relational databases and associated tools that can help laboratories contend with that data....

MAGIC Database and Interfaces: An Integrated Package for Gene Discovery and Expression (2004)

Chun Liang, Haiming Wang, Dmitri S. Kolychev, Feng Sun, Robert Freeman, ...

The rapidly increasing rate at which biological data is being produced requires a corresponding growth in relational databases and associated tools that can help laboratories contend with that data....

The Cdc6p nucleotide-binding motif is required for loading Mcm proteins onto chromatin

Weinreich, Michael, Liang, Chun, Stillman, Bruce

Cdc6p has an essential function in the mechanism and regulation of the initiation of DNA replication. Budding yeast Cdc6p binds to chromatin near autonomously replicating sequence elements in late M...

Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle

Weinreich, Michael, Liang, Chun, Chen, Hsu-Hsin, Stillman, Bruce

Cdc6p and the origin recognition complex (ORC) are essential for assembly of a pre-replicative complex (preRC) at origins of replication, before the initiation of DNA synthesis. In the absence of...

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

Liang, Chun, Stillman, Bruce

Faithful inheritance of genetic information requires that DNA be copied only once each cell cycle. Initiation of DNA replication involves the establishment of a prereplication complex (pre-RC) and...

Sorghum Expressed Sequence Tags Identify Signature Genes for Drought, Pathogenesis, and Skotomorphogenesis from a Milestone Set of 16,801 Unique Transcripts1[w]

Pratt, Lee H., Liang, Chun, Shah, Manish, Sun, Feng, Wang, Haiming, Reid, St. Patrick, ...

Improved knowledge of the sorghum transcriptome will enhance basic understanding of how plants respond to stresses and serve as a source of genes of value to agriculture. Toward this goal, Sorghum...

The Cdc6p nucleotide-binding motif is required for loading Mcm proteins onto chromatin

Weinreich, Michael, Liang, Chun, Stillman, Bruce

Cdc6p has an essential function in the mechanism and regulation of the initiation of DNA replication. Budding yeast Cdc6p binds to chromatin near autonomously replicating sequence elements in late M...

Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle

Weinreich, Michael, Liang, Chun, Chen, Hsu-Hsin, Stillman, Bruce

Cdc6p and the origin recognition complex (ORC) are essential for assembly of a pre-replicative complex (preRC) at origins of replication, before the initiation of DNA synthesis. In the absence of...

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

Liang, Chun, Stillman, Bruce

Faithful inheritance of genetic information requires that DNA be copied only once each cell cycle. Initiation of DNA replication involves the establishment of a prereplication complex (pre-RC) and...

Sorghum Expressed Sequence Tags Identify Signature Genes for Drought, Pathogenesis, and Skotomorphogenesis from a Milestone Set of 16,801 Unique Transcripts1[w]

Pratt, Lee H., Liang, Chun, Shah, Manish, Sun, Feng, Wang, Haiming, Reid, St. Patrick, ...

Improved knowledge of the sorghum transcriptome will enhance basic understanding of how plants respond to stresses and serve as a source of genes of value to agriculture. Toward this goal, Sorghum...

WebTraceMiner: a web service for processing and mining EST sequence trace files

Liang, Chun, Wang, Gang, Liu, Lin, Ji, Guoli, Liu, Yuansheng, Chen, Jinqiao, ...

Expressed sequence tags (ESTs) remain a dominant approach for characterizing the protein-encoding portions of various genomes. Due to inherent deficiencies, they also present serious challenges for...

Cdc48p is required for the cell cycle commitment point at Start via degradation of the G1-CDK inhibitor Far1p

Fu, Xinrong, Ng, Christine, Feng, Daorong, Liang, Chun

The budding yeast Cdc48p and its mammalian homologue p97 are involved in many important cellular activities. Because previous cdc48 mutants have exclusive G2/M arrest, Cdc48p was thought to play an...

MAGIC Database and Interfaces: An Integrated Package for Gene Discovery and Expression

Cordonnier-Pratt, Marie-Michèle, Liang, Chun, Wang, Haiming, Kolychev, Dmitri S., Sun, Feng, Freeman, Robert, ...

The rapidly increasing rate at which biological data is being produced requires a corresponding growth in relational databases and associated tools that can help laboratories contend with that data....

Unique Features of Nuclear mRNA Poly(A) Signals and Alternative Polyadenylation in Chlamydomonas reinhardtii

Shen, Yingjia, Liu, Yuansheng, Liu, Lin, Liang, Chun, Li, Qingshun Q.

To understand nuclear mRNA polyadenylation mechanisms in the model alga Chlamydomonas reinhardtii, we generated a data set of 16,952 in silico-verified poly(A) sites from EST sequencing traces based...

Expressed Sequence Tags With cDNA Termini: Previously Overlooked Resources for Gene Annotation and Transcriptome Exploration in Chlamydomonas reinhardtii

Liang, Chun, Liu, Yuansheng, Liu, Lin, Davis, Adam C., Shen, Yingjia, Li, Qingshun Quinn

Many of Chlamydomonas reinhardtii expressed sequence tags (ESTs) in GenBank dbEST and community EST assemblies were either over- or undertrimmed in terms of their cDNA termini, which are defined as...

Autographa californica Multiple Nucleopolyhedrovirus 38K Is a Novel Nucleocapsid Protein That Interacts with VP1054, VP39, VP80, and Itself▿ †

Wu, Wenbi, Liang, Hanquan, Kan, Junsuo, Liu, Chao, Yuan, Meijin, Liang, Chun, ...

It has been shown that the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) 38K (ac98) is required for nucleocapsid assembly. However, the exact role of 38K in nucleocapsid assembly...

Sequence Analysis of Bacterial Artificial Chromosome Clones from the Apospory-Specific Genomic Region of Pennisetum and Cenchrus1[W][OA]

Conner, Joann A., Goel, Shailendra, Gunawan, Gunawati, Cordonnier-Pratt, Marie-Michele, Johnson, Virgil Ed, Liang, Chun, ...

Apomixis, asexual reproduction through seed, is widespread among angiosperm families. Gametophytic apomixis in Pennisetum squamulatum and Cenchrus ciliaris is controlled by the apospory-specific...

WebGMAP: a web service for mapping and aligning cDNA sequences to genomes

Liang, Chun, Liu, Lin, Ji, Guoli

The genomes of thousands of organisms are being sequenced, often with accompanying sequences of cDNAs or ESTs. One of the great challenges in bioinformatics is to make these genomic sequences and...