Chunlei Su

Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii

Su, Chunlei, Howe, Daniel K., Dubey, J. P., Ajioka, James W., Sibley, L. David

Strains of Toxoplasma gondii can be grouped into three predominant clonal lineages with members of the type I group being uniformly lethal in mice. To elucidate the basis of this extreme virulence, a...

Role of Cytokines and Major Histocompatibility Complex Restriction in Mouse Resistance to Infection with a Natural Recombinant Strain (Type I-III) of Toxoplasma gondii

Fux, Blima, Rodrigues, Cibele V., Portela, Ricardo W., Silva, Neide M., Su, Chunlei, Sibley, David, ...

Herein we characterized various genetic markers and the biological behavior of a natural recombinant strain of Toxoplasma gondii (P-Br). From nine genetic markers analyzed, three (B1, ROP1, and SAG1)...

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii

Khan, Asis, Taylor, Sonya, Su, Chunlei, Mackey, Aaron J., Boyle, Jon, Cole, Robert, ...

Toxoplasma gondii is a highly successful protozoan parasite in the phylum Apicomplexa, which contains numerous animal and human pathogens. T.gondii is amenable to cellular, biochemical, molecular and...

Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii

Su, Chunlei, Howe, Daniel K., Dubey, J. P., Ajioka, James W., Sibley, L. David

Strains of Toxoplasma gondii can be grouped into three predominant clonal lineages with members of the type I group being uniformly lethal in mice. To elucidate the basis of this extreme virulence, a...

Role of Cytokines and Major Histocompatibility Complex Restriction in Mouse Resistance to Infection with a Natural Recombinant Strain (Type I-III) of Toxoplasma gondii

Fux, Blima, Rodrigues, Cibele V., Portela, Ricardo W., Silva, Neide M., Su, Chunlei, Sibley, David, ...

Herein we characterized various genetic markers and the biological behavior of a natural recombinant strain of Toxoplasma gondii (P-Br). From nine genetic markers analyzed, three (B1, ROP1, and SAG1)...

Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii

Khan, Asis, Taylor, Sonya, Su, Chunlei, Mackey, Aaron J., Boyle, Jon, Cole, Robert, ...

Toxoplasma gondii is a highly successful protozoan parasite in the phylum Apicomplexa, which contains numerous animal and human pathogens. T.gondii is amenable to cellular, biochemical, molecular and...

Genetic approaches to studying virulence and pathogenesis in Toxoplasma gondii.

Sibley, L David, Mordue, Dana G, Su, Chunlei, Robben, Paul M, Howe, Dan K

Toxoplasma gondii is a common protozoan parasite that causes disease in immunocompromised humans. Equipped with a wide array of experimental tools, T. gondii has rapidly developed as a model parasite...

Toxoplasma gondii Strains Defective in Oral Transmission Are Also Defective in Developmental Stage Differentiation▿

Fux, Blima, Nawas, Julie, Khan, Asis, Gill, Darcy B., Su, Chunlei, Sibley, L. David

Toxoplasma gondii undergoes differentiation from rapidly growing tachyzoites to slowly growing bradyzoites during its life cycle in the intermediate host, and conversion can be induced in vitro by...