Sriram, Venkataraman, Cho, Sungyoo, Li, Ping, O'Donnell, Patrick W., Dunn, Claire, Hayakawa, Kyoko, ...
Neoplastic transformation of cells is accompanied by an aberration of cell surface glycolipid composition. These tumor-associated, altered glycosphingolipids are often shed into the tumor cell...
Hegde, Nagendra R., Tomazin, Roman A., Wisner, Todd W., Dunn, Claire, Boname, Jessica M., Lewinsohn, David M., ...
Human cytomegalovirus (HCMV) establishes persistent lifelong infections and replicates slowly. To withstand robust immunity, HCMV utilizes numerous immune evasion strategies. The HCMV gene cassette...
Sriram, Venkataraman, Cho, Sungyoo, Li, Ping, O'Donnell, Patrick W., Dunn, Claire, Hayakawa, Kyoko, ...
Neoplastic transformation of cells is accompanied by an aberration of cell surface glycolipid composition. These tumor-associated, altered glycosphingolipids are often shed into the tumor cell...
Hegde, Nagendra R., Tomazin, Roman A., Wisner, Todd W., Dunn, Claire, Boname, Jessica M., Lewinsohn, David M., ...
Human cytomegalovirus (HCMV) establishes persistent lifelong infections and replicates slowly. To withstand robust immunity, HCMV utilizes numerous immune evasion strategies. The HCMV gene cassette...
Dunn, Claire, Brunetto, Maurizia, Reynolds, Gary, Christophides, Theodoros, Kennedy, Patrick T., Lampertico, Pietro, ...
Hepatitis B virus (HBV) causes chronic infection in more than 350 million people worldwide. It replicates in hepatocytes but is non-cytopathic; liver damage is thought to be immune mediated. Here, we...
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL
Hegde, Nagendra R., Dunn, Claire, Lewinsohn, David M., Jarvis, Michael A., Nelson, Jay A., Johnson, David C.
Human cytomegalovirus (HCMV) infects endothelial, epithelial, and glial cells in vivo. These cells can express MHC class II proteins, but are unlikely to play important roles in priming host...
Dunn, Claire, Chalupny, N. Jan, Sutherland, Claire L., Dosch, Stephanie, Sivakumar, P.V., Johnson, David C., ...
The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I–related ligands, including the...
Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection
Lopes, A. Ross, Kellam, Paul, Das, Abhishek, Dunn, Claire, Kwan, Antonia, Turner, Joanna, ...
HBV-specific CD8+ T cells are critical for a successful immune response to HBV infection. They are markedly diminished in number in patients who fail to control the virus, but the mechanisms...
Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
Das, Abhishek, Hoare, Matthew, Davies, Nathan, Lopes, A. Ross, Dunn, Claire, Kennedy, Patrick T.F., ...
The inflamed liver in chronic hepatitis B virus (HBV) infection (CHB) is characterized by a large influx of non–virus-specific CD8 T cells. Little is known about the functional capacity of these...