Claire Simons

6-Azathymidine-4'-thionucleosides: synthesis and antiviral evaluation (2008)

Simons, Claire

The synthesis of dideoxy-6-azathymidine 4'-thionucleoside 1-(2,3-dideoxy-4-thio-beta-D-erythro-pentofuranosyl)-(6-azathymidine) (2), and the L-nucleoside,...

Inhibition of vitamin D3 metabolism enhances VDR signalling in androgen-independent prostate cancer cells (2006)

Simons, Claire, Yee, SW, Campbell, MJ

Inhibition of vitamin D3 metabolism enhances VDR signalling in androgen-independent prostate cancer cells (2006)

Simons, Claire, Yee, SW, Campbell, MJ

Potent CYP19 (aromatase) 1-[(benzofuran-2-yl)(phenylmethyl)-pyridine, -imidazole, and –triazole inhibitors: synthesis and biological evaluation (2006)

Simons, Claire, Saberi, MR, Vinh, TK, Yee, SW

Potent CYP19 (aromatase) 1-[(benzofuran-2-yl)(phenylmethyl)-pyridine, -imidazole, and –triazole inhibitors: synthesis and biological evaluation (2006)

Simons, Claire, Saberi, MR, Vinh, TK, Yee, SW

Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays (2005)

Yee, Sook Wah, Jarno, Laetitia, Gomaa, Mohamed Sayed, Elford, Carole, Ooi, Liling, Coogan, Michael Peter, ...

Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays (2005)

Yee, Sook Wah, Jarno, Laetitia, Gomaa, Mohamed Sayed, Elford, Carole, Ooi, Liling, Coogan, Michael Peter, ...

Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays (2005)

Yee, Sook Wah, Jarno, Laetitia, Gomaa, Mohamed Sayed, Elford, Carole, Ooi, Liling, Coogan, Michael Peter, ...

Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays (2005)

Yee, Sook Wah, Jarno, Laetitia, Gomaa, Mohamed Sayed, Elford, Carole, Ooi, Liling, Coogan, Michael Peter, ...

6-Azapyrimidine-2'-deoxy-4'-thionucleosides: potent antiviral agents in TK+ and TK- HSV and VZV viral strains (2004)

Simons, Claire, Hughes, M, Hursthouse, E, Maslan, HL

6-Azapyrimidine-2'-deoxy-4'-thionucleosides: potent antiviral agents in TK+ and TK- HSV and VZV viral strains (2004)

Simons, Claire, Hughes, M, Hursthouse, E, Maslan, HL

6-azapyrimidine-2'-deoxy-4'-thionucleosides: antiviral agents against TK+ and TK- HSV and VZV strains (2004)

Hughes, David, Hursthouse, Mike, Simons, Claire

The synthesis of a series of novel 1-(2-deoxy-4-thio-beta-D-erythro-pentofuranosyl)-(6-azapyrimidine) nucleosides is described. X-ray crystallographic data of the thymidine derivative allowed...

Novel imidazo[1,2-c]pyrimidine base-modified nucleosides: synthesis and antiviral evaluation (2004)

Simons, Claire

The preparation of a series of novel 6-(beta-D-ribofuranosyl)-2-alkyl/aryl-6H-imidazo[1,2-c]pyrimidin-5-one nucleosides and the 2-nitrile nucleosides,...

Novel bicyclic sugar modified nucleosides: synthesis, conformational analysis and antiviral evaluation (2004)

Thet Htar, Thet, Simons, Claire

Methodology previously described by us was applied to the formation of novel conformationally restrained bicyclic sugar modified nucleosides, with introduction of an oxazole and a thiocarbamate ring...