Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation (2007)
Saban, Ricardo, D'Andrea, Michael R, Andrade-Gordon, Patricia, Derian, Claudia K, Dozmorov, Igor, Ihnat, Michael A, ...
Abstract Background In general, inflammation plays a role in most bladder pathologies and represents a defense reaction to injury that often times is two edged. In particular, bladder neurogenic...
Regulatory network of inflammation downstream of proteinase-activated receptors (2007)
Saban, Ricardo, D'Andrea, Michael R, Andrade-Gordon, Patricia, Derian, Claudia K, Dozmorov, Igor, Ihnat, Michael A, ...
Abstract Background Protease-activated receptors (PAR) are present in the urinary bladder, and their expression is altered in response to inflammation. PARs are a unique class of G protein-coupled...
John A. Barrett, Claudia K. Derian, Robert S. Swillo, Richard F. Woltmann, Mark H. Perrone
Using The globally ischaemic isolated guinea-pig heart we conducted studies to assess the role of activated neutrophils (PMNs) and the role of the endothelium in reperfusion injury. Reperfusion...
Andrade-Gordon, Patricia, Maryanoff, Bruce E., Derian, Claudia K., Zhang, Han-Cheng, Addo, Michael F., Darrow, Andrew L., ...
Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus that...
Andrade-Gordon, Patricia, Maryanoff, Bruce E., Derian, Claudia K., Zhang, Han-Cheng, Addo, Michael F., Darrow, Andrew L., ...
Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus that...
Regulatory network of inflammation downstream of proteinase-activated receptors
Saban, Ricardo, D'Andrea, Michael R, Andrade-Gordon, Patricia, Derian, Claudia K, Dozmorov, Igor, Ihnat, Michael A, ...
Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation
Saban, Ricardo, D'Andrea, Michael R, Andrade-Gordon, Patricia, Derian, Claudia K, Dozmorov, Igor, Ihnat, Michael A, ...
D’Andrea, Michael R., Derian, Claudia K., Santulli, Rosemary J., Andrade-Gordon, Patricia
The serine proteases thrombin and trypsin are among many factors that malignant cells secrete into the extracellular space to mediate metastatic processes such as cellular invasion, extracellular...
Sukocheva, Olga, Wadham, Carol, Holmes, Andrew, Albanese, Nathaniel, Verrier, Emily, Feng, Feng, ...
The transactivation of enhanced growth factor receptor (EGFR) by G protein–coupled receptor (GPCR) ligands is recognized as an important signaling mechanism in the regulation of complex biological...
Barrett, John A., Derian, Claudia K., Swillo, Robert S., Woltmann, Richard F., Perrone, Mark H.
Using The globally ischaemic isolated guinea-pig heart we conducted studies to assess the role of activated neutrophils (PMNs) and the role of the endothelium in reperfusion injury. Reperfusion...
Scotton, Chris J., Krupiczojc, Malvina A., Königshoff, Melanie, Mercer, Paul F., Lee, Y.C. Gary, Kaminski, Naftali, ...
Uncontrolled activation of the coagulation cascade contributes to the pathophysiology of several conditions, including acute and chronic lung diseases. Coagulation zymogens are considered to be...