Scientific Commons: Claudia Lamina

Abstract Background We investigated the influence of genotyping errors on the type I error rate and empirical power of two haplotype based association methods applied to candidate regions. We...

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins (2009)

Kollerits, Barbara, Coassin, Stefan, Beckmann, Noam D., Teumer, Alexander, Kiechl, Stefan, Döring, Angela, ...

Adiponutrin (PNPLA3) is a predominantly liver-expressed transmembrane protein with phospholipase activity that is regulated by fasting and feeding. Recent genome-wide association studies identified...

Common variants near MC4R are associated with fat mass, weight and risk of obesity (2008)

Loos, Ruth J.F., Lindgren, Cecilia M., Li, Shengxu, Wheeler, Eleanor, Zhao, Jing Hua, Prokopenko, Inga, ...

To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the...

Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up (2006)

Lamina, Claudia, Meisinger, Christa, Heid, Iris M., Löwel, Hannelore, Rantner, Barbara, Koenig, Wolfgang, ...

Aims Peripheral arterial occlusive disease is associated with a high risk of cardiovascular morbidity and mortality. We prospectively examined the association of the ankle-brachial index (ABI) and...

Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up (2006)

Lamina, Claudia, Meisinger, Christa, Heid, Iris M., Löwel, Hannelore, Rantner, Barbara, Koenig, Wolfgang, ...

Aims Peripheral arterial occlusive disease is associated with a high risk of cardiovascular morbidity and mortality. We prospectively examined the association of the ankle-brachial index (ABI) and...

Haplotype Reconstruction Error as a Classical Misclassification Problem: Introducing Sensitivity and Specificity as Error Measures

Lamina, Claudia, Bongardt, Friedhelm, Küchenhoff, Helmut, Heid, Iris M.

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

Linsel-Nitschke, Patrick, Götz, Anika, Erdmann, Jeanette, Braenne, Ingrid, Braund, Peter, Hengstenberg, Christian, ...

Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods

Marquard, Vivien, Beckmann, Lars, Heid, Iris M, Lamina, Claudia, Chang-Claude, Jenny

Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

Linsel-Nitschke, Patrick, Götz, Anika, Erdmann, Jeanette, Braenne, Ingrid, Braund, Peter, Hengstenberg, Christian, ...

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

Kolz, Melanie, Johnson, Toby, Sanna, Serena, Teumer, Alexander, Vitart, Veronique, Perola, Markus, ...

Elevated serum uric acid levels cause gout and are a risk factor for cardiovascular disease and diabetes. To investigate the polygenetic basis of serum uric acid levels, we conducted a meta-analysis...

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

Lindgren, Cecilia M., Heid, Iris M., Randall, Joshua C., Lamina, Claudia, Steinthorsdottir, Valgerdur, Qi, Lu, ...

To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist...

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

Lindgren, Cecilia M., Heid, Iris M., Randall, Joshua C., Lamina, Claudia, Steinthorsdottir, Valgerdur, Qi, Lu, ...

Estimating the Single Nucleotide Polymorphism Genotype Misclassification From Routine Double Measurements in a Large Epidemiologic Sample

Heid, Iris M., Lamina, Claudia, Küchenhoff, Helmut, Fischer, Guido, Klopp, Norman, Kolz, Melanie, ...

Previously, estimation of genotype misclassification of single nucleotide polymorphisms (SNPs) as encountered in epidemiologic practice and involving thousands of subjects was lacking. The authors...

Claudia Lamina

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