Claudia R. Morris

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

Kato, Gregory J., McGowan, Vicki, Machado, Roberto F., Little, Jane A., Taylor, James, Morris, Claudia R., ...

Pulmonary hypertension is prevalent in adult patients with sickle cell disease and is strongly associated with early mortality and markers of hemolysis, in particular, serum lactate dehydrogenase...

Evaluation of a Novel, Integrated Approach Using Functionalized Magnetic Beads, Bench-Top MALDI-TOF-MS with Prestructured Sample Supports, and Pattern Recognition Software for Profiling Potential Biomarkers in Human Plasma

Zhang, Xinyi, Leung, Sau-Mei, Morris, Claudia R., Shigenaga, Mark K.

The advantage of using proteins and peptides as biomarkers is that they can be found readily in blood, urine, and other biological fluids. Such sample types are easily obtained and represent a...

Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease

Morris, Claudia R., Suh, Jung H., Hagar, Ward, Larkin, Sandra, Bland, D. Anton, Steinberg, Martin H., ...

Erythrocyte glutathione depletion has been linked to hemolysis and oxidative stress. Glutamine plays an additional antioxidant role through preservation of intracellular nicotinamide adenine...