Cordula Tschuch

Off-target effects of siRNA specific for GFP (2008)

Tschuch, Cordula, Schulz, Angela, Pscherer, Armin, Werft, Wiebke, Benner, Axel, Hotz-Wagenblatt, Agnes, ...

Abstract Background Gene knock down by RNAi is a highly effective approach to silence gene expression in experimental as well as therapeutic settings. However, this widely used methodology entails...

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism

Mertens, Daniel, Wolf, Stephan, Tschuch, Cordula, Mund, Cora, Kienle, Dirk, Ohl, Sibylle, ...

Genomic material from chromosome band 13q14.3 distal to the retinoblastoma locus is recurrently lost in a variety of human neoplasms, indicating an as-yet-unidentified tumor-suppressor mechanism. No...

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism

Mertens, Daniel, Wolf, Stephan, Tschuch, Cordula, Mund, Cora, Kienle, Dirk, Ohl, Sibylle, ...

Genomic material from chromosome band 13q14.3 distal to the retinoblastoma locus is recurrently lost in a variety of human neoplasms, indicating an as-yet-unidentified tumor-suppressor mechanism. No...