Weller, Sandra, Faili, Ahmad, Garcia, Corinne, Braun, Moritz C., Le Deist, Françoise, De Saint Basile, Geneviève, ...
Somatically mutated IgM+-only and IgM+IgD+CD27+ B lymphocytes comprise ≈25% of the human peripheral B cell pool. These cells phenotypically resemble class-switched B cells and have therefore been...
Defect in IgV gene somatic hypermutation in Common Variable Immuno-Deficiency syndrome
Levy, Yves, Gupta, Neetu, Le Deist, Françoise, Garcia, Corinne, Fischer, Alain, Weill, Jean-Claude, ...
Common Variable Immuno-Deficiency (CVID) is the most common symptomatic primary antibody-deficiency syndrome, but the basic immunologic defects underlying this syndrome are not well defined. We...
Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases
Alyanakian, Marie-Alexandra, You, Sylvaine, Damotte, Diane, Gouarin, Christine, Esling, Anne, Garcia, Corinne, ...
Depletion of selected regulatory CD4+ T cell subsets induces the spontaneous onset of various immune or autoimmune disorders. It is not clear, however, whether a given subset, notably CD4+CD25+...
Weller, Sandra, Faili, Ahmad, Garcia, Corinne, Braun, Moritz C., Le Deist, Françoise, De Saint Basile, Geneviève, ...
Somatically mutated IgM+-only and IgM+IgD+CD27+ B lymphocytes comprise ≈25% of the human peripheral B cell pool. These cells phenotypically resemble class-switched B cells and have therefore been...
Defect in IgV gene somatic hypermutation in Common Variable Immuno-Deficiency syndrome
Levy, Yves, Gupta, Neetu, Le Deist, Françoise, Garcia, Corinne, Fischer, Alain, Weill, Jean-Claude, ...
Common Variable Immuno-Deficiency (CVID) is the most common symptomatic primary antibody-deficiency syndrome, but the basic immunologic defects underlying this syndrome are not well defined. We...
Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases
Alyanakian, Marie-Alexandra, You, Sylvaine, Damotte, Diane, Gouarin, Christine, Esling, Anne, Garcia, Corinne, ...
Depletion of selected regulatory CD4+ T cell subsets induces the spontaneous onset of various immune or autoimmune disorders. It is not clear, however, whether a given subset, notably CD4+CD25+...
You, Sylvaine, Leforban, Bertrand, Garcia, Corinne, Bach, Jean-François, Bluestone, Jeffrey A., Chatenoud, Lucienne
Previous results have shown that CD4+CD25+ regulatory T cells (Tregs) control autoimmunity in a spontaneous model of type 1 diabetes, the nonobese diabetic (NOD) mouse. Moreover, anti-CD3 reverses...
Di Santo, James P., Aifantis, Iannis, Rosmaraki, Eleftheria, Garcia, Corinne, Feinberg, Jacqueline, Fehling, Hans Jörg, ...
Intracellular signals emanating from cytokine and antigen receptors are integrated during the process of intrathymic development. Still, the relative contributions of cytokine receptor signaling to...
Tilloy, Florence, Treiner, Emmanuel, Park, Se-Ho, Garcia, Corinne, Lemonnier, François, De La Salle, Henri, ...
We describe here a new subset of T cells, found in humans, mice, and cattle. These cells bear a canonical T cell receptor (TCR) α chain containing hAV7S2 and AJ33 in humans and the homologous...
Characterization of T Cell Differentiation in the Murine Gut
Lambolez, Florence, Azogui, Orly, Joret, Anne-Marie, Garcia, Corinne, Von Boehmer, Harald, Di Santo, James, ...
Gut intraepithelial CD8 T lymphocytes (T-IEL) are distinct from thymus-derived cells and are thought to derive locally from cryptopatch (CP) precursors. The intermediate stages of differentiation...
Buer, Jan, Lanoue, Astrid, Franzke, Anke, Garcia, Corinne, Boehmer, Harald Von, Sarukhan, Adelaida
Continuous antigenic stimulation in vivo can result in the generation of so-called “anergic” CD4+ or CD8+ T cells that fail to proliferate upon antigenic stimulation and fail to develop cytolytic...