Shelley S. Tworoger, Yutaka Yasui, Cornelia M. Ulrich, Heather Nakamura, Kristin Lacroix, Ric Johnston, ...
Recruitment into public health intervention trials can be costly and time-consuming. We examined two components of recruitment for an exercise trial: (a) a randomized pilot study of mailing...
A mathematical model of glutathione metabolism (2008)
Reed, Michael C, Thomas, Rachel L, Pavisic, Jovana, James, S Jill, Ulrich, Cornelia M, Nijhout, H Frederik
Abstract Background Glutathione (GSH) plays an important role in anti-oxidant defense and detoxification reactions. It is primarily synthesized in the liver by the transsulfuration pathway and...
Curtin, Karen, Slattery, Martha L., Ulrich, Cornelia M., Bigler, Jeannette, Levin, Theodore R., Wolff, Roger K., ...
This study investigated associations between CpG island methylator phenotype (CIMP) colon cancer and genetic polymorphisms relevant to one-carbon metabolism and thus, potentially the provision of...
Genetic variability in prostaglandin synthesis, fish intake and risk of colorectal polyps (2007)
Poole, Elizabeth M., Bigler, Jeannette, Whitton, John, Sibert, Justin G., Kulmacz, Richard J., Potter, John D., ...
Dietary polyunsaturated fatty acids (PUFAs) can be converted to prostaglandins and leukotrienes. Metabolism of omega-6 (n-6) PUFAs results in the production of pro-inflammatory mediators whereas...
Genetic variability in prostaglandin synthesis, fish intake, and risk of colorectal polyps (2007)
Poole, Elizabeth M., Bigler, Jeannette, Whitton, John, Sibert, Justin G., Kulmacz, Richard J., Potter, John D., ...
Dietary polyunsaturated fatty acids (PUFAs) can be converted to prostaglandins and leukotrienes. Metabolism of omega-6 (n-6) PUFAs results in the production of pro-inflammatory mediators while...
In silico experimentation with a model of hepatic mitochondrial folate metabolism (2006)
Nijhout, H Frederik, Reed, Michael C, Lam, Shi-Ling, Shane, Barry, Gregory, Jesse F, Ulrich, Cornelia M
Abstract Background In eukaryotes, folate metabolism is compartmentalized and occurs in both the cytosol and the mitochondria. The function of this compartmentalization and the great changes that...
Randomized trial of exercise in sedentary middle aged women: effects on quality of life (2006)
Bowen, Deborah J, Fesinmeyer, Megan D, Yasui, Yutaka, Tworoger, Shelley, Ulrich, Cornelia M, Irwin, Melinda L, ...
Abstract Increasing physical activity is currently considered to be a possible prevention strategy for cancer, obesity, and cardiovascular disease, either alone or in combination with dietary...
Sparks, Rachel, Ulrich, Cornelia M, Bigler, Jeannette, Tworoger, Shelley S, Yasui, Yutaka, Rajan, Kumar B, ...
Abstract Introduction UDP-glucuronosyltransferase (UGT) and sulfotransferase (SULT) enzymes are involved in removing sex hormones from circulation. Polymorphic variation in five UGT and SULT genes...
TGF{beta}1 polymorphism (L10P) and risk of colorectal adenomatous and hyperplastic polyps (2004)
Sparks, Rachel, Bigler, Jeannette, Sibert, Justin G., Potter, John D., Yasui, Yutaka, Ulrich, Cornelia M.
Background Transforming growth factor-β1 (TGFβ1) is a multifunctional signalling molecule with a wide array of roles. Animal experiments suggest that TGFβ1 plays a biphasic role in carcinogenesis...
TGF{beta}1 polymorphism (L10P) and risk of colorectal adenomatous and hyperplastic polyps (2004)
Sparks, Rachel, Bigler, Jeannette, Sibert, Justin G, Potter, John D, Yasui, Yutaka, Ulrich, Cornelia M
Background Transforming growth factor-β1 (TGFb1) is a multifunctional signalling molecule with a wide array of roles. Animal experiments suggest that TGFb1 plays a biphasic role in carcinogenesis by...
Effects of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women (2003)
Irwin, Melinda L., Yasui, Yutaka, Ulrich, Cornelia M., Bowen, Deborah, Rudolph, Rebecca E., Schwartz, Robert S., ...
Context The increasing prevalence of obesity is a major public health concern. Physical activity may promote weight and body fat loss. Objective To examine the effects of exercise on total and...
5,10-Methylenetetrahydrofolate Reductase Polymorphisms and Leukemia Risk: A HuGE Minireview (2003)
Robien, Kim, Ulrich, Cornelia M.
Leukemias commonly arise as a result of DNA translocations, inversions, or deletions in genes regulating blood cell development or homeostasis. Folate deficiency has been associated with uracil...
Sparks, Rachel, Ulrich, Cornelia M, Bigler, Jeannette, Tworoger, Shelley S, Yasui, Yutaka, Rajan, Kumar B, ...
Randomized trial of exercise in sedentary middle aged women: effects on quality of life
Bowen, Deborah J, Fesinmeyer, Megan D, Yasui, Yutaka, Tworoger, Shelley, Ulrich, Cornelia M, Irwin, Melinda L, ...
Increasing physical activity is currently considered to be a possible prevention strategy for cancer, obesity, and cardiovascular disease, either alone or in combination with dietary changes. This...
In silico experimentation with a model of hepatic mitochondrial folate metabolism
Nijhout, H Frederik, Reed, Michael C, Lam, Shi-Ling, Shane, Barry, Gregory, Jesse F, Ulrich, Cornelia M
Sparks, Rachel, Ulrich, Cornelia M, Bigler, Jeannette, Tworoger, Shelley S, Yasui, Yutaka, Rajan, Kumar B, ...
Randomized trial of exercise in sedentary middle aged women: effects on quality of life
Bowen, Deborah J, Fesinmeyer, Megan D, Yasui, Yutaka, Tworoger, Shelley, Ulrich, Cornelia M, Irwin, Melinda L, ...
Increasing physical activity is currently considered to be a possible prevention strategy for cancer, obesity, and cardiovascular disease, either alone or in combination with dietary changes. This...