Cristiano Simone

Cdk9-55: a new player in muscle regeneration (2008)

Giacinti, Cristina, MusarĂ², Antonio, De Falco, Giulia, Jourdan, Isabelle, Molinaro, Mario, Bagella, Luigi Marco, ...

Adult skeletal muscle contains a specialized population of myogenic quiescent stem cells, termed satellite cells, which contribute to repair myofibers after injury. During muscle regeneration,...

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008)

Spanel-Borowski, Katharina, Smith, Mark A., Simone, Cristiano, Simonsen, Anne, Simon, Hans-Uwe, ...

Research in autophagy continues to accelerate, and as a result many new scientists are entering the field. Accordingly, it is important to establish a standard set of criteria for monitoring...

Identification of murine cdk10: association with Ets2 transcription factor and effects on the cell cycle (2006)

Bagella, Luigi Marco, Giacinti, Cristina, Simone, Cristiano, Giordano, Antonio

Cyclin-dependent kinases (cdks) are the catalytic subunits of a large family of serine/threonine protein kinases whose best-characterized members are key regulators of eukaryotic cell cycle...

MyoD recruits the cdk9/cyclin T2 complex on Myogenic-genes regulatory regions (2005)

Giacinti, Cristina, Bagella, Luigi Marco, Puri, Pier Lorenzo, Giordano, Antonio, Simone, Cristiano

During skeletal myogenesis, muscle-regulatory factors bHLH and MEF2 promote the expression of muscle-specific genes by recruiting several chromatin-modifying complexes on specific DNA regulatory...

Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis (2000)

Guanti, Ginevra, Resta, Nicoletta, Simone, Cristiano, Cariola, Filomena, Demma, Ignazio, Fiorente, Paola, ...

So far, somatic mutations of the PTEN gene have been found in several different neoplasms but not in colorectal tumours. As exons 7 and 8 of the PTEN coding sequence contain an (A)6 repeat and...

Differentiation-Induced Radioresistance in Muscle Cells

Latella, Lucia, Lukas, Jiri, Simone, Cristiano, Puri, Pier Lorenzo, Bartek, Jiri

DNA damage induces cell cycle arrest and DNA repair or apoptosis in proliferating cells. Terminally differentiated cells are permanently withdrawn from the cell cycle and partly resistant to...

Differentiation-Induced Radioresistance in Muscle Cells

Latella, Lucia, Lukas, Jiri, Simone, Cristiano, Puri, Pier Lorenzo, Bartek, Jiri

DNA damage induces cell cycle arrest and DNA repair or apoptosis in proliferating cells. Terminally differentiated cells are permanently withdrawn from the cell cycle and partly resistant to...