Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
Lin, Pengnian, Buxton, Jake A., Acheson, Ann, Radziejewski, Czeslaw, Maisonpierre, Peter C., Yancopoulos, George D., ...
Angiogenesis is required for tumor growth and metastasis, and inhibition of angiogenesis is a promising approach for anticancer therapy. Tie2 (a.k.a Tek) is an endothelium-specific receptor tyrosine...
VEGF-Trap: A VEGF blocker with potent antitumor effects
Holash, Jocelyn, Davis, Sam, Papadopoulos, Nick, Croll, Susan D., Ho, Lillian, Russell, Michelle, ...
Vascular endothelial growth factor (VEGF) plays a critical role during normal embryonic angiogenesis and also in the pathological angiogenesis that occurs in a number of diseases, including cancer....
Cursiefen, Claus, Chen, Lu, Borges, Leonardo P., Jackson, David, Cao, Jingtai, Radziejewski, Czeslaw, ...
Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization, is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds VEGFR1 and VEGFR2 and is...
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
Lin, Pengnian, Buxton, Jake A., Acheson, Ann, Radziejewski, Czeslaw, Maisonpierre, Peter C., Yancopoulos, George D., ...
Angiogenesis is required for tumor growth and metastasis, and inhibition of angiogenesis is a promising approach for anticancer therapy. Tie2 (a.k.a Tek) is an endothelium-specific receptor tyrosine...
VEGF-Trap: A VEGF blocker with potent antitumor effects
Holash, Jocelyn, Davis, Sam, Papadopoulos, Nick, Croll, Susan D., Ho, Lillian, Russell, Michelle, ...
Vascular endothelial growth factor (VEGF) plays a critical role during normal embryonic angiogenesis and also in the pathological angiogenesis that occurs in a number of diseases, including cancer....
Cursiefen, Claus, Chen, Lu, Borges, Leonardo P., Jackson, David, Cao, Jingtai, Radziejewski, Czeslaw, ...
Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization, is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds VEGFR1 and VEGFR2 and is...