D. Brent Weatherly

The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi (2009)

Minning, Todd A, Weatherly, D Brent, Atwood, James, Orlando, Ron, Tarleton, Rick L

Abstract Background Chronic chagasic cardiomyopathy is a debilitating and frequently fatal outcome of human infection with the protozoan parasite, Trypanosoma cruzi . Microarray analysis of gene...

Chromosome level assembly of the hybrid Trypanosoma cruzigenome (2009)

Weatherly, D Brent, Boehlke, Courtney, Tarleton, Rick L

Abstract Background In contrast to the essentially fully assembled genome sequences of the kinetoplastid pathogens Leishmania major and Trypanosoma brucei the assembly of the Trypanosoma cruzi genome...

A semi-quantitative GeLC-MS analysis of temporal proteome expression in the emerging nosocomial pathogen Ochrobactrum anthropi (2007)

Graham, Robert, Sharma, Mohit K, Ternan, Nigel G, Weatherly, D Brent, Tarleton, Rick L, McMullan, Geoff

Abstract Background The α-Proteobacteria are capable of interaction with eukaryotic cells, with some members, such as Ochrobactrum anthropi , capable of acting as human pathogens. O. anthropi has...

CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes (2006)

Diana L. Martin, D. Brent Weatherly, Susana A. Laucella, Melissa A. Cabinian, Matthew T. Crim, Susan Sullivan, ...

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of...

TcruziDB: an integrated, post-genomics community resource for Trypanosoma cruzi (2006)

Agüero, Fernán, Zheng, Wenlong, Weatherly, D. Brent, Mendes, Pablo, Kissinger, Jessica C.

TcruziDB (http://TcruziDB.org) is an integrated post-genomics database for the parasitic organism, Trypanosoma cruzi, the causative agent of Chagas' disease. TcruziDB was established in 2003 as a...

TcruziDB: an integrated Trypanosoma cruzi genome resource (2004)

Luchtan, Michael, Warade, Chetna, Weatherly, D. Brent, Degrave, Wim M., Tarleton, Rick L., Kissinger, Jessica C.

TcruziDB (http://TcruziDB.org) is an integrated genome database for the parasitic organism Trypanosoma cruzi, the causative agent of Chagas’ disease. The database currently incorporates all...

Dyn-MPI: Supporting MPI on Non Dedicated Clusters (2003)

D. Brent Weatherly, David K. Lowenthal, Mario Nakazawa, Franklin Lowenthal

Distributing data is one of the fundamental problems in implementing efficient distributed-memory parallel programs. The problem becomes more difficult in environments where the participating nodes...

Transaction Management for a Main-Memory Database (2002)

Piyush Burte, Boanerges Aleman-meza, D. Brent Weatherly, Rong Wu, Supervising Professor, John A. Miller

As part of research by members of the Department of Computer Science at the University of Georgia, we have developed a Java-based Transaction Manager that fits into the multi-layered design of MMODB,...

SUIF-Adapt: An Integrated Compiler/Run-Time System for Global and Dynamic Data Distributions (2002)

David K. Lowenthal, Donald G. Morris, D. Brent Weatherly, Franklin Lowenthal

Distributing data is one of the key problems in implementing efficient distributed-memory parallel programs. The problem is especially difficult in programs where (1) data redistribution between...

TcruziDB: an integrated Trypanosoma cruzi genome resource

Luchtan, Michael, Warade, Chetna, Weatherly, D. Brent, Degrave, Wim M., Tarleton, Rick L., Kissinger, Jessica C.

TcruziDB (http://TcruziDB.org) is an integrated genome database for the parasitic organism Trypanosoma cruzi, the causative agent of Chagas’ disease. The database currently incorporates all...

TcruziDB: an integrated, post-genomics community resource for Trypanosoma cruzi

Agüero, Fernán, Zheng, Wenlong, Weatherly, D. Brent, Mendes, Pablo, Kissinger, Jessica C.

TcruziDB () is an integrated post-genomics database for the parasitic organism, Trypanosoma cruzi, the causative agent of Chagas' disease. TcruziDB was established in 2003 as a flat-file database...

CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

Martin, Diana L, Weatherly, D. Brent, Laucella, Susana A, Cabinian, Melissa A, Crim, Matthew T, Sullivan, Susan, ...

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of...

TcruziDB: an integrated Trypanosoma cruzi genome resource

Luchtan, Michael, Warade, Chetna, Weatherly, D. Brent, Degrave, Wim M., Tarleton, Rick L., Kissinger, Jessica C.

TcruziDB (http://TcruziDB.org) is an integrated genome database for the parasitic organism Trypanosoma cruzi, the causative agent of Chagas’ disease. The database currently incorporates all...

TcruziDB: an integrated, post-genomics community resource for Trypanosoma cruzi

Agüero, Fernán, Zheng, Wenlong, Weatherly, D. Brent, Mendes, Pablo, Kissinger, Jessica C.

TcruziDB () is an integrated post-genomics database for the parasitic organism, Trypanosoma cruzi, the causative agent of Chagas' disease. TcruziDB was established in 2003 as a flat-file database...

CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

Martin, Diana L, Weatherly, D. Brent, Laucella, Susana A, Cabinian, Melissa A, Crim, Matthew T, Sullivan, Susan, ...

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of...

A semi-quantitative GeLC-MS analysis of temporal proteome expression in the emerging nosocomial pathogen Ochrobactrum anthropi

Graham, Robert Leslie James, Sharma, Mohit K, Ternan, Nigel G, Weatherly, D Brent, Tarleton, Rick L, McMullan, Geoff

A semi-quantitative gel-based analysis identifies distinct proteomic profiles associated with specific growth points for the nosocomial pathogen Ochrobactrum anthropi.

HLA Class I-T Cell Epitopes from trans-Sialidase Proteins Reveal Functionally Distinct Subsets of CD8+ T Cells in Chronic Chagas Disease

Alvarez, María G., Postan, Miriam, Weatherly, D. Brent, Albareda, María C., Sidney, John, Sette, Alessandro, ...

At present, 16–20 million people in Central and South America are infected with Trypanosoma cruzi, the causative agent of Chagas disease in humans. The primary clinical consequence of the infection...

High Throughput Selection of Effective Serodiagnostics for Trypanosoma cruzi infection

Cooley, Gretchen, Etheridge, R. Drew, Boehlke, Courtney, Bundy, Becky, Weatherly, D. Brent, Minning, Todd, ...

The diagnosis of Trypanosoma cruzi infection (the cause of human Chagas disease) is difficult because the symptoms of the infection are often absent or non-specific, and because the parasites...