Histological abnormalities of muscle from limb, thorax and diaphragm in chronic heart failure (1996)
Lindsay, D. C., Lovegrove, C. A., Dunn, M. J., Bennett, J. G., Pepper, J. R., Yacoub, M. H., ...
The aim of the study was to compare histological findings in limb and respiratory muscles from control subjects and patients with heart failure of two different aetiologies. Biopsies of the...
Syndrome X in women is associated with oestrogen deficiency (1995)
ROSANO, G. M. C., COLLINS, P., KASKI, J. C., LINDSAY, D. C., SARREL, P. M., POOLE-WILSON, P. A.
This study was undertaken to ascertain whether gynaecological history or a reduction in ovarian hormones are triggers of angina in menopausal women with a positive exercise test and normal coronary...
LINDSAY, D. C., ANAND, I. S., BENNETT, J. G., PEPPER, J. R., YACOUB, M. H., ROTHERY, S. M., ...
Chronic heart failure (CHF) is characterized by increased systemic vascular resistance and diminished blood flow to exercising skeletal muscle. The pathogenesis of the increased resistance is not...
Lindsay, D C, Jiang, C, Brunotte, F, Adamopoulos, S, Coats, A J S, Rajagopalan, B, ...
Objective: The aim was to document the response of aortic rings from a rat model of heart failure to endothelium dependent and endothelium independent vasodilating agents. The effects of an exercise...
Should colonoscopy be the first investigation for colonic disease?
Lindsay, D C, Freeman, J G, Cobden, I, Record, C O
Many patients with suspected colonic disease undergo rigid sigmoidoscopy, barium enema examination, and ultimately total colonoscopy, but the need for preliminary radiology has not been formally...
Mardini, H A, Lindsay, D C, Deighton, C M, Record, C O
It has been suggested that polymer coating might retard jejunal absorption of 5-amino salicylic acid (5-ASA) and thus promote delivery to its colonic site of action. Twenty three patients with active...
Endothelial control of lower limb blood flow in chronic heart failure.
Lindsay, D. C., Holdright, D. R., Clarke, D., Anand, I. S., Poole-Wilson, P. A., Collins, P.
BACKGROUND: Limitation of the blood supply to skeletal muscle in chronic heart failure may contribute to the symptoms of fatigue and diminished exercise capacity. The pathophysiology underlying this...
Coronary flow reserve in patients with chest pain and normal coronary arteries.
Holdright, D R, Lindsay, D C, Clarke, D, Fox, K, Poole-Wilson, P A, Collins, P
BACKGROUND--Many studies have shown that coronary flow reserve is reduced in patients with chest pain and angiographically normal coronary arteries. The methods used to assess coronary blood flow...
Endothelium-independent relaxation of rabbit coronary artery by 17 beta-oestradiol in vitro.
Jiang, C. W., Sarrel, P. M., Lindsay, D. C., Poole-Wilson, P. A., Collins, P.
1. We assessed the relaxant effect of 17 beta-oestradiol (10(-7), 10(-6) and 10(-5) M) on rabbit isolated coronary arteries precontracted with prostaglandin F2 alpha (3 x 10(-6) M), high...
Incidence and types of acute viral hepatitis in Newcastle upon Tyne.
Hosker, H. S., Lindsay, D. C., Game, F., Codd, A. A., Dale, G., Record, C. O.
The incidence and types of viral hepatitis in the city of Newcastle upon Tyne have been studied by serological analysis of (a) all blood samples sent to the virological laboratory for hepatitis...
Should colonoscopy be the first investigation for colonic disease?
Lindsay, D C, Freeman, J G, Cobden, I, Record, C O
Many patients with suspected colonic disease undergo rigid sigmoidoscopy, barium enema examination, and ultimately total colonoscopy, but the need for preliminary radiology has not been formally...