Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.
Mazumder, A, Cooney, D, Agbaria, R, Gupta, M, Pommier, Y
The effects of 3'-azido-3'-deoxythymidine (AZT) and three of its intracellular metabolites, azido- thymidine mono-, di-, and triphosphates, on the human immunodeficiency virus type 1 integrase have...
Tridandapani, S, Kelley, T, Pradhan, M, Cooney, D, Justement, L B, Coggeshall, K M
Recently, we and others have demonstrated that negative signaling in B cells selectively induces the tyrosine phosphorylation of a novel inositol polyphosphate phosphatase, p145SHIP. In this study,...
Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.
Mazumder, A, Cooney, D, Agbaria, R, Gupta, M, Pommier, Y
The effects of 3'-azido-3'-deoxythymidine (AZT) and three of its intracellular metabolites, azido- thymidine mono-, di-, and triphosphates, on the human immunodeficiency virus type 1 integrase have...
Tridandapani, S, Kelley, T, Pradhan, M, Cooney, D, Justement, L B, Coggeshall, K M
Recently, we and others have demonstrated that negative signaling in B cells selectively induces the tyrosine phosphorylation of a novel inositol polyphosphate phosphatase, p145SHIP. In this study,...
The economics of inclusion body processing
Lee, GH, Cooney, D, Middelberg, APJ, Choe, WS
Many recombinant proteins are often over-expressed in host cells, such as Escherichia coli, and are found as insoluble and inactive protein aggregates known as inclusion bodies (IBs). Recently, a...