Sevoflurane degradation to compound A in anaesthesia breathing systems (1996)
Cunningham, D. D., Huang, S., Webster, J., Mayoral, J., Grabenkort, R. W.
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.
Van Nostrand, W E, Farrow, J S, Wagner, S L, Bhasin, R, Goldgaber, D, Cotman, C W, ...
The amyloid beta protein and the amyloid beta-protein precursor (APP) are major constituents of senile plaques and cerebrovascular deposits in patients with Alzheimer disease and Down syndrome. Most...
Thrombin modulates and reverses neuroblastoma neurite outgrowth.
Previous studies have shown that neuroblastoma cells and several types of primary neuronal cells in culture rapidly extend neurites when switched from serum-containing to serum-free medium. The...
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.
Wagner, S L, Geddes, J W, Cotman, C W, Lau, A L, Gurwitz, D, Isackson, P J, ...
Protease nexin-1 (PN-1) is a cell-secreted protein that inhibits certain proteases, particularly thrombin, by forming SDS-stable complexes with the catalytic site serine of the protease. PN-1 was...
Low, D A, Baker, J B, Koonce, W C, Cunningham, D D
Protease-nexin (PN), a component released by normal human fibroblasts into culture medium, forms covalent linkages with thrombin (Th) and the urinary plasminogen activator urokinase, apparently with...
Epidermal growth factor carrier protein (CP) is an arginine endopeptidase bound to epidermal growth factor (EGF) in vivo that processes pro-EGF to EGF and potentiates EGF action. Here, we provide a...
Human fibroblasts accelerate the inhibition of thrombin by protease nexin.
Protease nexin (PN) is a protein protease inhibitor secreted by human fibroblasts in culture that complexes and inhibits certain regulatory serine proteases. The PN-protease complexes then bind to...
A simple two-step purification of protease nexin.
Farrell, D H, Van Nostrand, W E, Cunningham, D D
This paper describes a simple purification procedure for protease nexin, a serine proteinase inhibitor secreted by cultured human fibroblasts that regulates proteinase activity at and near the cell...
Glycosaminoglycans on fibroblasts accelerate thrombin inhibition by protease nexin-1.
Protease nexin-1 (PN-1) is a proteinase inhibitor that is secreted by human fibroblasts in culture. PN-1 inhibits certain regulatory serine proteinases by forming a covalent complex with the...
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.
Van Nostrand, W E, Farrow, J S, Wagner, S L, Bhasin, R, Goldgaber, D, Cotman, C W, ...
The amyloid beta protein and the amyloid beta-protein precursor (APP) are major constituents of senile plaques and cerebrovascular deposits in patients with Alzheimer disease and Down syndrome. Most...
Thrombin modulates and reverses neuroblastoma neurite outgrowth.
Previous studies have shown that neuroblastoma cells and several types of primary neuronal cells in culture rapidly extend neurites when switched from serum-containing to serum-free medium. The...
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.
Wagner, S L, Geddes, J W, Cotman, C W, Lau, A L, Gurwitz, D, Isackson, P J, ...
Protease nexin-1 (PN-1) is a cell-secreted protein that inhibits certain proteases, particularly thrombin, by forming SDS-stable complexes with the catalytic site serine of the protease. PN-1 was...
Low, D A, Baker, J B, Koonce, W C, Cunningham, D D
Protease-nexin (PN), a component released by normal human fibroblasts into culture medium, forms covalent linkages with thrombin (Th) and the urinary plasminogen activator urokinase, apparently with...
Epidermal growth factor carrier protein (CP) is an arginine endopeptidase bound to epidermal growth factor (EGF) in vivo that processes pro-EGF to EGF and potentiates EGF action. Here, we provide a...
Human fibroblasts accelerate the inhibition of thrombin by protease nexin.
Protease nexin (PN) is a protein protease inhibitor secreted by human fibroblasts in culture that complexes and inhibits certain regulatory serine proteases. The PN-protease complexes then bind to...
A simple two-step purification of protease nexin.
Farrell, D H, Van Nostrand, W E, Cunningham, D D
This paper describes a simple purification procedure for protease nexin, a serine proteinase inhibitor secreted by cultured human fibroblasts that regulates proteinase activity at and near the cell...
Glycosaminoglycans on fibroblasts accelerate thrombin inhibition by protease nexin-1.
Protease nexin-1 (PN-1) is a proteinase inhibitor that is secreted by human fibroblasts in culture. PN-1 inhibits certain regulatory serine proteinases by forming a covalent complex with the...
Choi, B. H., Suzuki, M., Kim, T., Wagner, S. L., Cunningham, D. D.
Protease nexin-1 (PN-1) is a potent thrombin inhibitor that is identical to the glia-derived neurite-promoting factor or glia-derived nexin. Here we report immunocytochemical studies of adult human...