Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells.
Kaufman, R J, Murtha, P, Ingolia, D E, Yeung, C Y, Kellems, R E
We demonstrate that an adenosine deaminase (ADA) cDNA gene can function as a dominant selectable and amplifiable marker for gene transfer experiments in mammalian cells. Cells that incorporate the...
Ingolia, D E, Al-Ubaidi, M R, Yeung, C Y, Bigo, H A, Wright, D, Kellems, R E
A genomic library was prepared with DNA from a genetically enriched mouse cell line in which amplified copies of the adenosine deaminase (ADA) gene account for over 5% of the genome. Overlapping...
Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells.
Kaufman, R J, Murtha, P, Ingolia, D E, Yeung, C Y, Kellems, R E
We demonstrate that an adenosine deaminase (ADA) cDNA gene can function as a dominant selectable and amplifiable marker for gene transfer experiments in mammalian cells. Cells that incorporate the...
Ingolia, D E, Al-Ubaidi, M R, Yeung, C Y, Bigo, H A, Wright, D, Kellems, R E
A genomic library was prepared with DNA from a genetically enriched mouse cell line in which amplified copies of the adenosine deaminase (ADA) gene account for over 5% of the genome. Overlapping...