Clostridium difficile colitis after kidney and kidney-pancreas transplantation (1999)
Chavers, B, Gillingham, K, Sutherland, D E, Dunn, D L, ...
OBJECTIVE: To determine the timing and risk factors involved in the development of Clostridium difficile (CD) colitis in kidney and kidney-pancreas transplant recipients. BACKGROUND DATA: The...
Colon perforation after renal transplantation: a single-institution review (1997)
Lledo-Garcia, E, Benedetti, E, West, M, Hakim, N S, Sutherland, D E, ...
Colon perforation (CP) is an uncommon but dramatic complication after renal transplantation. Of 1530 consecutive kidney transplants performed at our center, 8 recipients had an CP (incidence of...
Hakim, N S, Benedetti, E, Kashtan, C E, Cook, M, ...
Congenital absence of useful ilio-caval venous segment is a very infrequent congenital anomaly and makes unfit grafting of a kidney transplant in iliac fossa. We report the case of a 18 years old...
Najarian, J S, Gruessner, A C, Nakhleh, R E, Troppmann, C, Hakim, N S, ...
BACKGROUND. Urinary amylase (UA) remains the most common biochemical parameter to detect rejection in bladder-drained pancreas allografts. With the development of the cystoscopic transduodenal...
Kidney transplantation in the absence of the infrarenal vena cava (1995)
Benedetti, E, Kashtan, C E, Llédo-Garcia, E, Hakim, N, Schroeder, C H, ...
Department of Surgery, University of Minnesota, Minneapolis, USA.
Benedetti, E, Papalois, B E, Gruessner, A C, Hakim, N, ...
University of Minnesota, Department of Surgery, Minneapolis.
Benedetti, E, Gillingham, K J, Payne, W D, Dunn, D L, ...
We reviewed urologic complications of 1183 consecutive primary or secondary renal transplants performed with bladder anastomoses at the University of Minnesota Hospital between 1985 and 1993. The...
Diem, P, Redmon, J B, Abid, M, Moran, A, Sutherland, D E, Halter, J B, ...
Successful pancreas transplantation in type I diabetic patients restores normal fasting glucose levels and biphasic insulin responses to glucose. However, virtually no data from pancreas recipients...
Structural-functional relationships in diabetic nephropathy.
Mauer, S M, Steffes, M W, Ellis, E N, Sutherland, D E, Brown, D M, Goetz, F C
Renal biopsies in 45 patients with insulin-dependent diabetes mellitus (IDDM) were examined by semiquantitative light microscopy and quantitative electron microscopic stereologic morphometry. In...
Simultaneous pancreas-kidney transplantation from live donors.
Gruessner, R W, Kendall, D M, Drangstveit, M B, Gruessner, A C, Sutherland, D E
OBJECTIVE: In this first report of a clinical series of simultaneous pancreas-kidney transplants (SPKs) from live donors, the authors assess donor and recipient outcome as well as the spectrum of...
Troppmann, C, Gruessner, A C, Dunn, D L, Sutherland, D E, Gruessner, R W
OBJECTIVES: To study significant surgical complications requiring early (< or = 3 months posttransplant) relaparotomy (relap) after pancreas transplants, and to develop clinically relevant surgical...
Short- and long-term outcomes of kidney transplants with multiple renal arteries.
Benedetti, E, Troppmann, C, Gillingham, K, Sutherland, D E, Payne, W D, Dunn, D L, ...
OBJECTIVE: The authors determined whether the use of kidney allografts with multiple renal arteries adversely effects post-transplant graft and patient outcome or increases the incidence of vascular...
Autologous islet transplantation to prevent diabetes after pancreatic resection.
Wahoff, D C, Papalois, B E, Najarian, J S, Kendall, D M, Farney, A C, Leone, J P, ...
BACKGROUND: Extensive pancreatic resection for small-duct chronic pancreatitis is often required for pain relief, but the risk of diabetes is a major deterrent. OBJECTIVE: Incidence of pain relief,...
Gores, P F, Gillingham, K J, Dunn, D L, Moudry-Munns, K C, Najarian, J S, Sutherland, D E
The impact of multiple donor and recipient variables on functional survival of 307 cadaveric pancreas allografts transplanted in 253 recipients at the authors' institution between July 25, 1978 and...
Stephanian, E, Gruessner, R W, Brayman, K L, Gores, P, Dunn, D L, Najarian, J S, ...
Between September 1984 and August 1991, 265 whole pancreaticoduodenal transplants were done at our institution, with bladder drainage of exocrine secretions through a duodenocystostomy. Seventeen...
One hundred pancreas transplants at a single institution.
Sutherland, D E, Goetz, F C, Najarian, J S
Clinical pancreas transplantation at the University of Minnesota began in 1966. An initial series of 14 whole pancreas grafts was reported in part to the American Surgical Association in 1970. Only...
Najarian, J S, Fryd, D S, Strand, M, Canafax, D M, Ascher, N L, Payne, W D, ...
Between September 26, 1980 and December 31, 1983, 230 splenectomized, transfused renal allograft recipients were randomized to treatment with either cyclosporin-prednisone (N = 121, 68 diabetic and...
Intra-abdominal infections in pancreas transplant recipients.
Hesse, U J, Sutherland, D E, Simmons, R L, Najarian, J S
During a 7-year period, 116 pancreas transplants were performed in 98 diabetic patients (49 with and 49 without previous kidney transplants) at the University of Minnesota. The posttransplant...
The outcome of 304 primary renal transplants in children (1968-1985).
Najarian, J S, So, S K, Simmons, R L, Fryd, D S, Nevins, T E, Ascher, N L, ...
Of 304 children who received primary renal transplants at the University of Minnesota between January 1, 1968, and December 31, 1985, 48 (16%) were under the age of 24 months, 60 (20%) were 2-5 years...
Seven years' experience with antilymphoblast globulin for renal transplantation from cadaver donors.
Najarian, J S, Simmons, R L, Condie, R M, Thompson, E J, Fryd, D S, Howard, R J, ...
Antibody of the IgGab type can be isolated from horses immunized with cultured human lymphoblasts plus complete Freund's adjuvant. The essential steps for the production of a safe, potent anti-human...
Kidney allograft survival in dogs treated with total lymphoid irradiation.
Howard, R J, Sutherland, D E, Lum, C T, Lewis, W I, Kim, T H, Slavin, S, ...
Total lymphoid irradiation (TLI) is immunosuppressive and, in rodent, can induce a state where transplantation of allogeneic bone marrow results in chimerism and permanent acceptance of organ...
Najarian, J S, Sutherland, D E, Baumgartner, D, Burke, B, Rynasiewicz, J J, Matas, A J, ...
Total or near total pancreatectomy is the surest way to relieve the pain of chronic pancreatitis but is rarely applied because the metabolic consequences are so severe. For most patients drainage...
Najarian, J S, Ferguson, R M, Sutherland, D E, Slavin, S, Kim, T, Kersey, J, ...
Twenty-two patients at high risk to reject renal allografts have been treated with fractionated total lymphoid irradiation (FTLI) prior to transplantation of primary (2), secondary (16) or teritary...
Long-term success with double pediatric cadaver donor renal transplants.
Schneider, J R, Sutherland, D E, Simmons, R L, Fryd, D S, Najarian, J S
Many institutions are reluctant to use pediatric cadaver kidneys for transplantation because of a fear of an increased risk of technical complications or because these grafts leave the recipient with...
Matas, A J, Sibley, R, Mauer, M, Sutherland, D E, Simmons, R L, Najarian, J S
Following renal transplantation, immunosuppression is usually increased to treat presumed rejection episodes. However, a) many conditions mimic rejection in the post-transplant period, and b) many...
Renal allograft survival in patients with positive B cell crossmatch to their donor.
Morrow, C E, Sutherland, D E, Fryd, D S, Noreen, H, Segall, M, Bach, F H, ...
B cell crossmatches were performed at cold (4 C) and warm (22 C and 37 C) temperatures on 193 renal allograft recipients with negative T cell crossmatches to their donor; 152 of the patients were...
A 10-year experience with 290 pancreas transplants at a single institution.
Sutherland, D E, Dunn, D L, Goetz, F C, Kennedy, W, Ramsay, R C, Steffes, M W, ...
Since our report at the 1984 American Surgical Association meeting of 100 pancreas transplants from 1966 through 1983, another 190 have been performed. The current series, begun in 1978, now numbers...
Causes of renal allograft loss. Progress in the 1980s, challenges for the 1990s.
Schweitzer, E J, Matas, A J, Gillingham, K J, Payne, W D, Gores, P F, Dunn, D L, ...
A variety of refinements in the care of kidney transplant recipients have been instituted over the past decade. The authors studied the overall impact of these refinements on kidney allograft losses...
100 HLA-identical sibling transplants. Prognostic factors other than histocompatibility.
Ascher, N L, Simmons, R L, Noreen, H, VanHook, J, Howard, R J, Sutherland, D E, ...
Analysis of 100 patients receiving HLA identical sibling transplants was performed. Excellent graft survival demonstrated in the group attests to the importance of matching serological determined...
Fistulisation of shunt vasculature: a unique approach to fistula development.
Buselmeier, T J, Rynasiewicz, J J, Howard, R H, Sutherland, D E, Davin, T D, Lynch, R L, ...
Diem, P, Redmon, J B, Abid, M, Moran, A, Sutherland, D E, Halter, J B, ...
Successful pancreas transplantation in type I diabetic patients restores normal fasting glucose levels and biphasic insulin responses to glucose. However, virtually no data from pancreas recipients...
Structural-functional relationships in diabetic nephropathy.
Mauer, S M, Steffes, M W, Ellis, E N, Sutherland, D E, Brown, D M, Goetz, F C
Renal biopsies in 45 patients with insulin-dependent diabetes mellitus (IDDM) were examined by semiquantitative light microscopy and quantitative electron microscopic stereologic morphometry. In...
Simultaneous pancreas-kidney transplantation from live donors.
Gruessner, R W, Kendall, D M, Drangstveit, M B, Gruessner, A C, Sutherland, D E
OBJECTIVE: In this first report of a clinical series of simultaneous pancreas-kidney transplants (SPKs) from live donors, the authors assess donor and recipient outcome as well as the spectrum of...
Troppmann, C, Gruessner, A C, Dunn, D L, Sutherland, D E, Gruessner, R W
OBJECTIVES: To study significant surgical complications requiring early (< or = 3 months posttransplant) relaparotomy (relap) after pancreas transplants, and to develop clinically relevant surgical...
Short- and long-term outcomes of kidney transplants with multiple renal arteries.
Benedetti, E, Troppmann, C, Gillingham, K, Sutherland, D E, Payne, W D, Dunn, D L, ...
OBJECTIVE: The authors determined whether the use of kidney allografts with multiple renal arteries adversely effects post-transplant graft and patient outcome or increases the incidence of vascular...
Autologous islet transplantation to prevent diabetes after pancreatic resection.
Wahoff, D C, Papalois, B E, Najarian, J S, Kendall, D M, Farney, A C, Leone, J P, ...
BACKGROUND: Extensive pancreatic resection for small-duct chronic pancreatitis is often required for pain relief, but the risk of diabetes is a major deterrent. OBJECTIVE: Incidence of pain relief,...
Gores, P F, Gillingham, K J, Dunn, D L, Moudry-Munns, K C, Najarian, J S, Sutherland, D E
The impact of multiple donor and recipient variables on functional survival of 307 cadaveric pancreas allografts transplanted in 253 recipients at the authors' institution between July 25, 1978 and...
Stephanian, E, Gruessner, R W, Brayman, K L, Gores, P, Dunn, D L, Najarian, J S, ...
Between September 1984 and August 1991, 265 whole pancreaticoduodenal transplants were done at our institution, with bladder drainage of exocrine secretions through a duodenocystostomy. Seventeen...
One hundred pancreas transplants at a single institution.
Sutherland, D E, Goetz, F C, Najarian, J S
Clinical pancreas transplantation at the University of Minnesota began in 1966. An initial series of 14 whole pancreas grafts was reported in part to the American Surgical Association in 1970. Only...
Najarian, J S, Fryd, D S, Strand, M, Canafax, D M, Ascher, N L, Payne, W D, ...
Between September 26, 1980 and December 31, 1983, 230 splenectomized, transfused renal allograft recipients were randomized to treatment with either cyclosporin-prednisone (N = 121, 68 diabetic and...
Intra-abdominal infections in pancreas transplant recipients.
Hesse, U J, Sutherland, D E, Simmons, R L, Najarian, J S
During a 7-year period, 116 pancreas transplants were performed in 98 diabetic patients (49 with and 49 without previous kidney transplants) at the University of Minnesota. The posttransplant...
The outcome of 304 primary renal transplants in children (1968-1985).
Najarian, J S, So, S K, Simmons, R L, Fryd, D S, Nevins, T E, Ascher, N L, ...
Of 304 children who received primary renal transplants at the University of Minnesota between January 1, 1968, and December 31, 1985, 48 (16%) were under the age of 24 months, 60 (20%) were 2-5 years...
Seven years' experience with antilymphoblast globulin for renal transplantation from cadaver donors.
Najarian, J S, Simmons, R L, Condie, R M, Thompson, E J, Fryd, D S, Howard, R J, ...
Antibody of the IgGab type can be isolated from horses immunized with cultured human lymphoblasts plus complete Freund's adjuvant. The essential steps for the production of a safe, potent anti-human...
Kidney allograft survival in dogs treated with total lymphoid irradiation.
Howard, R J, Sutherland, D E, Lum, C T, Lewis, W I, Kim, T H, Slavin, S, ...
Total lymphoid irradiation (TLI) is immunosuppressive and, in rodent, can induce a state where transplantation of allogeneic bone marrow results in chimerism and permanent acceptance of organ...
Najarian, J S, Sutherland, D E, Baumgartner, D, Burke, B, Rynasiewicz, J J, Matas, A J, ...
Total or near total pancreatectomy is the surest way to relieve the pain of chronic pancreatitis but is rarely applied because the metabolic consequences are so severe. For most patients drainage...
Najarian, J S, Ferguson, R M, Sutherland, D E, Slavin, S, Kim, T, Kersey, J, ...
Twenty-two patients at high risk to reject renal allografts have been treated with fractionated total lymphoid irradiation (FTLI) prior to transplantation of primary (2), secondary (16) or teritary...
Long-term success with double pediatric cadaver donor renal transplants.
Schneider, J R, Sutherland, D E, Simmons, R L, Fryd, D S, Najarian, J S
Many institutions are reluctant to use pediatric cadaver kidneys for transplantation because of a fear of an increased risk of technical complications or because these grafts leave the recipient with...
Matas, A J, Sibley, R, Mauer, M, Sutherland, D E, Simmons, R L, Najarian, J S
Following renal transplantation, immunosuppression is usually increased to treat presumed rejection episodes. However, a) many conditions mimic rejection in the post-transplant period, and b) many...
Renal allograft survival in patients with positive B cell crossmatch to their donor.
Morrow, C E, Sutherland, D E, Fryd, D S, Noreen, H, Segall, M, Bach, F H, ...
B cell crossmatches were performed at cold (4 C) and warm (22 C and 37 C) temperatures on 193 renal allograft recipients with negative T cell crossmatches to their donor; 152 of the patients were...
A 10-year experience with 290 pancreas transplants at a single institution.
Sutherland, D E, Dunn, D L, Goetz, F C, Kennedy, W, Ramsay, R C, Steffes, M W, ...
Since our report at the 1984 American Surgical Association meeting of 100 pancreas transplants from 1966 through 1983, another 190 have been performed. The current series, begun in 1978, now numbers...
Causes of renal allograft loss. Progress in the 1980s, challenges for the 1990s.
Schweitzer, E J, Matas, A J, Gillingham, K J, Payne, W D, Gores, P F, Dunn, D L, ...
A variety of refinements in the care of kidney transplant recipients have been instituted over the past decade. The authors studied the overall impact of these refinements on kidney allograft losses...
100 HLA-identical sibling transplants. Prognostic factors other than histocompatibility.
Ascher, N L, Simmons, R L, Noreen, H, VanHook, J, Howard, R J, Sutherland, D E, ...
Analysis of 100 patients receiving HLA identical sibling transplants was performed. Excellent graft survival demonstrated in the group attests to the importance of matching serological determined...
Fistulisation of shunt vasculature: a unique approach to fistula development.
Buselmeier, T J, Rynasiewicz, J J, Howard, R H, Sutherland, D E, Davin, T D, Lynch, R L, ...
Pancreas transplantation. An immunohistologic and histopathologic examination of 100 grafts.
Sibley, R. K., Sutherland, D. E.
The authors examined tissues obtained by biopsy, pancreatectomy, and autopsy from 100 pancreas grafts to determine the cause of dysfunction or failure of the graft. Immunohistologic examination of 42...
Handwerger, B S, Fernandes, G, Riehm, T, Yoon, J W, Sutherland, D E, Brown, D M
Increasing data suggest a possible viral aetiology of juvenile onset, insulin-dependent diabetes mellitus. The M variant of the encephalomyocarditis (EMC) virus infects murine pancreatic beta cells...
Grotting, J. C., Rosai, J., Matas, A. J., Frenzel, E. M., Payne, W. D., Sutherland, D. E., ...
Streptozotocin-induced diabetes in the rat can be reversed by the transplantation of isogenic islets of Langerhans from neonatal donors. We studied the morphology of intraportally transplanted islets...