Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA.
Szymkowski, D E, Lawrence, C W, Wood, R D
One cis-syn cyclobutane thymine dimer or one (6-4) thymine-thymine photoproduct was built into an identical sequence of a closed-circular M13 duplex DNA, and nucleotide excision repair synthesis...
Szymkowski, D E, Yarema, K, Essigmann, J M, Lippard, S J, Wood, R D
We have examined the ability of human cell extracts to repair the most frequent DNA adduct caused by the cancer chemotherapeutic agent cis-diamminedichloroplatinum(II). A circular DNA duplex with an...
Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts.
Moggs, J G, Szymkowski, D E, Yamada, M, Karran, P, Wood, R D
In order to understand the action of the chemotherapeutic drug cisplatin, it is necessary to determine why some types of cisplatin-DNA intrastrand crosslinks are repaired better than others. Using...
An XPG DNA repair defect causing mutagen hypersensitivity in mouse leukemia L1210 cells.
Vilpo, J A, Vilpo, L M, Szymkowski, D E, O'Donovan, A, Wood, R D
One of the most widely used antitumor drugs is cis-diamminedichloroplatinum(II) (cisplatin), and mechanisms of cisplatin resistance have been investigated in numerous model systems. Many studies have...
Identification and characterization of a Dictyostelium discoideum ribosomal protein gene.
We have identified a developmentally repressed large-subunit ribosomal protein gene of Dictyostelium discoideum based on sequence similarity to other ribosomal proteins. Protein rpl7 is homologous to...
Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.
Biggerstaff, M, Szymkowski, D E, Wood, R D
The mammalian ERCC1-encoded polypeptide is required for nucleotide excision repair of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic...
Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA.
Szymkowski, D E, Lawrence, C W, Wood, R D
One cis-syn cyclobutane thymine dimer or one (6-4) thymine-thymine photoproduct was built into an identical sequence of a closed-circular M13 duplex DNA, and nucleotide excision repair synthesis...
Szymkowski, D E, Yarema, K, Essigmann, J M, Lippard, S J, Wood, R D
We have examined the ability of human cell extracts to repair the most frequent DNA adduct caused by the cancer chemotherapeutic agent cis-diamminedichloroplatinum(II). A circular DNA duplex with an...
Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts.
Moggs, J G, Szymkowski, D E, Yamada, M, Karran, P, Wood, R D
In order to understand the action of the chemotherapeutic drug cisplatin, it is necessary to determine why some types of cisplatin-DNA intrastrand crosslinks are repaired better than others. Using...
An XPG DNA repair defect causing mutagen hypersensitivity in mouse leukemia L1210 cells.
Vilpo, J A, Vilpo, L M, Szymkowski, D E, O'Donovan, A, Wood, R D
One of the most widely used antitumor drugs is cis-diamminedichloroplatinum(II) (cisplatin), and mechanisms of cisplatin resistance have been investigated in numerous model systems. Many studies have...
Identification and characterization of a Dictyostelium discoideum ribosomal protein gene.
We have identified a developmentally repressed large-subunit ribosomal protein gene of Dictyostelium discoideum based on sequence similarity to other ribosomal proteins. Protein rpl7 is homologous to...
Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.
Biggerstaff, M, Szymkowski, D E, Wood, R D
The mammalian ERCC1-encoded polypeptide is required for nucleotide excision repair of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic...