Peek, G.J., Clemens, F., Elbourne, D., Firmin, R., Hardy, P., Hibbert, C., ...
An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma,...
Peek, G.J., Clemens, F., Elbourne, D., Firmin, R., Hardy, P., Hibbert, C., ...
An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma,...
Peek, G.J., Clemens, F., Elbourne, D., Firmin, R., Hardy, P., Hibbert, C., ...
An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma,...
Does secondary school size make a difference? A systematic review. (2006)
Newman, M, Garrett, Z, Elbourne, D, Bradley, S, Noden, P, Taylor, J, ...
Does secondary school size make a difference? A systematic review (2006)
Newman, M, Garrett, Z, Elbourne, D, Bradley, S, Noden, Philip, Taylor, J, ...
Does secondary school size make a difference? A systematic review (2006)
Newman, M, Garrett, Z, Elbourne, D, Bradley, S, Noden, Philip, Taylor, J, ...
Harvey, S., Harrison, D.A., Singer, M., Ashcroft, J., Jones, C.M., Elbourne, D., ...
Background: Over the past 30 years the pulmonary artery catheter (PAC) has become a widely used haemodynamic monitoring device in the management of critically ill patients, though doubts exist about...
Newman, M, Elbourne, D, Leask, M
This paper reports on the findings of a scoping project that set out to investigate the phenomenon of under reporting of primary research in education more systematically, and to produce a draft set...
Elbourne, D., Dezateux, C., Arthur, R., Clarke, N.M.P., Gray, A., King, A., ...
Background: Clinical screening aims to identify and treat neonatal hip instability associated with increased risk of hip displacement, but risks failures of diagnosis and treatment (abduction...
The trials of Dr. Bernard Fisher: a European perspective on an American episode (1997)
BUYSE, Marc, Peto, R., Collins, R., Sackett, D., Darbyshire, J., Babiker, A., ...
The trials of Dr. Bernard Fisher: a European perspective on an American episode (1997)
BUYSE, Marc, Peto, R., Collins, R., Sackett, D., Darbyshire, J., Babiker, A., ...
West Berkshire perineal management trial.
Sleep, J, Grant, A, Garcia, J, Elbourne, D, Spencer, J, Chalmers, I
One thousand women were allocated at random to one of two perineal management policies, both intended to minimise trauma during spontaneous vaginal delivery. In one the aim was to restrict episiotomy...
West Berkshire perineal management trial.
Sleep, J, Grant, A, Garcia, J, Elbourne, D, Spencer, J, Chalmers, I
One thousand women were allocated at random to one of two perineal management policies, both intended to minimise trauma during spontaneous vaginal delivery. In one the aim was to restrict episiotomy...
Elbourne, D, Pritchard, C, Dauncey, M
This paper makes use of the opportunity provided by comparable obstetric data bases to examine area and social class variations in perinatal outcome and associated factors in areas smaller than those...
Comparing two methods of follow up in a multicentre randomised trial
Fooks, J., Mutch, L., Yudkin, P., Johnson, A., Elbourne, D.
AIMS—To evaluate a parental questionnaire as a means of providing outcome measures for a multicentre randomised controlled trial of treatment for post-haemorrhagic ventricular...
Randomised controlled trial of prophylactic etamsylate: follow up at 2 years of age
Elbourne, D, Ayers, S, Dellagrammaticas, H, Johnson, A, Leloup, M, Lenoir-Piat, S
AIM—To assess the role of etamsylate* in reducing the risk of haemorrhagic brain damage and its consequences. DESIGN—Follow up of babies recruited into a randomised controlled...
Perinatal pathology in the context of a clinical trial: attitudes of bereaved parents
Snowdon, C, Elbourne, D, Garcia, J
Background: Interviews with neonatologists in a related study had revealed a degree of discomfort with approaching bereaved parents for postmortem examinations (PMs) and a widespread concern that...
Perinatal pathology in the context of a clinical trial: attitudes of neonatologists and pathologists
Snowdon, C, Elbourne, D, Garcia, J
Objective: To describe the attitudes of neonatologists to trial related perinatal postmortem examinations (PMs), in the light of declining perinatal PM rates and poor levels of participation in...
Gardner, F, Dezateux, C, Elbourne, D, Gray, A, King, A, Quinn, A, ...
Background: The hip trial aimed to assess clinical effectiveness, economic and psychosocial costs, and benefits of ultrasound imaging (US) compared with conventional clinical assessment alone to...
Clinical trials and rare diseases. Trials of adequate size are possible with the right organisation.