D. F. Fischer

A direct androgenic involvement in the expression of human corticotropin-releasing hormone (2006)

Bao, A.M, Fischer, D.F., Wu, Y.H., Hol, E.M., Balesar, R., Unmehopa, U.A., ...

We investigated the possibility of a direct action of androgens on the expression of the human corticotropin-releasing hormone (CRH), which plays a central role in the hypothalamic pituitary-adrenal...

Ubiquitin proteasome system as a pharmacological target in neurodegeneration (2006)

Hol, E.M., Fischer, D.F., Ovaa, H., Scheper, W.

Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies (2006)

Leeuwen, F.W. Van, Tijn, P. Van, Sonnemans, M.A.F., Hobo, B., Mann, D.M.A., Broeckhoven, C. Van, ...

Alzheimer-associated APP+1 transgenic mice: Frameshift beta-amyloid precursor protein is secreted in cerebrospinal fluid without inducing neuropathology (2006)

Fischer, D.F., Hol, E.M., Hobo, B., Leeuwen, F.W. Van

Biomarkers present in the cerebrospinal fluid (CSF) of Alzheimer Disease patients could be instrumental in guiding diagnosis and monitoring of progression of the disease. We have previously reported...

Conformational diseases: An umbrella for various neurological disorders with an impaired ubiquitin-proteasome system (2006)

Pril, R. De, Fischer, D.F., Leeuwen, F.W. Van

It is increasingly appreciated that failures in the ubiquitin-proteasome system play a pivotal role in the neuropathogenesis of many neurological disorders. This system, involved in protein quality...

Molecular misreading: the frequency of dinucleotide deletions in neuronal mRNAs for beta-amyloid precursor protein and ubiquitin B (2005)

Gerez, L., Haan, A. De, Hol, E.M., Fischer, D.F., Leeuwen, F.W. Van, Steeg, H. Van, ...

Estrogen receptor-alpha splice variants in the medial mamillary nucleus of Alzheimer's disease patients: identification of a novel MB1 isoform (2005)

Ishunina, T.A., Swaab, D.F., Fischer, D.F.

Molecular changes underlying reduced Pineal Melatonin levels in Alzheimer's disease; Alterations in Preclinical and Clinical Stages (2003)

Feenstra, M.G.P., Torano, J.S., ...

Molecular changes underlying reduced pineal melatonin levels in Alzheimer disease: Alterations in preclinical and clinical stages (2003)

Wu, Y., Feenstra, M.G.P., Zhou, J.N., Liu, R-Y., Torano, J.S., ...

Frameshifted beta-amyloid precursor protein (APP+1) is a secretory protein, and the level of APP+1 in cerebrospinal fluid is linked to Alzheimer pathology (2003)

Hol, E.M., Dijk, R. Van, Gerez, L., Sluijs, J.A., Hobo, B., Tonk, M.T., ...

Molecular misreading: a new type of transcript mutation expressed during aging (2000)

Leeuwen, F.W. Van, Kamel, D., Sluijs, J.A., Sonnemans, M.A.F., Fischer, D.F., Benne, R., ...

Molecular misreading: a new type of transcript mutation expressed during aging [open peer commentary] (2000)

Leeuwen, F.W. Van, Fischer, D.F., Kamel, D., Sluijs, J.A., Sonnemans, M.A.F., Benne, R., ...

Molecular misreading: a new type of transcript mutation in gerontology (2000)

Leeuwen, F.W. Van, Fischer, D.F., Benne, R., Hol, E.M.

Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker (1998)

Fischer, D.F., Fischer, C.M., Winkler, G.S., Putte, P. Van De, Backendorf, C.

Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells

Fischer, D. F., Grimbergen, J. M., Klein, B., Falkenburg, J. H. F., ...

The chicken anemia virus protein apoptin induces a p53-independent, Bcl-2-insensitive type of apoptosis in various human tumor cells. Here, we show that, in vitro, apoptin fails to induce programmed...

Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker.

Fischer, D F, Van Drunen, C M, Winkler, G S, Backendorf, C

The small proline-rich protein genes ( SPRRs ) code for precursors of the cornified cell envelope, and are specifically expressed during keratinocyte terminal differentiation. The single intron of...

Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation.

Fischer, D F, Gibbs, S, Backendorf, C

Expression of the SPRR2A gene, a member of the small proline-rich family of cornified cell envelope precursor proteins, is strictly linked to keratinocyte terminal differentiation both in vivo and in...

SIMULATED IN-TRANSIT VIBRATION DAMAGE TO FRESH MARKET RASPBERRIES

Craig, W.L., Woolsey, M.D., Ashby, B.H., Fischer, D.F.

Agribusiness,