D. F. Schoors

Single dose pharmacokinetics, safety and tolerability of MK-0476, a new leukotriene D4-receptor antagonist, in healthy volunteers.

Schoors, D F, De Smet, M, Reiss, T, Margolskee, D, Cheng, H, Larson, P, ...

MK-4076 or sodium 1-(1(R)-(3-(2-(7-chloro-2-quinolinyl)-(E)- ethenyl)phenyl) 3-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl) cycloproprane) acetate is a novel, potent, and specific...

Effect of multiple doses of losartan on the pharmacokinetics of single doses of digoxin in healthy volunteers.

De Smet, M, Schoors, D F, De Meyer, G, Verbesselt, R, Goldberg, M R, Fitzpatrick, V, ...

1. Losartan (DuP 753, MK-954) is a novel, potent and highly selective AT1 angiotensin II receptor antagonist. The effect of multiple oral doses of losartan on digoxin pharmacokinetics was evaluated...

Influence of nicardipine on the pharmacokinetics and pharmacodynamics of propranolol in healthy volunteers.

Schoors, D F, Vercruysse, I, Musch, G, Massart, D L, Dupont, A G

1. The influence of a single oral dose of nicardipine 30 mg on the pharmacokinetics and pharmacodynamics of propranolol 80 mg was investigated in twelve healthy volunteers. 2. Co-administration of...

Identification of a D1 dopamine receptor, not linked to adenylate cyclase, on lactotroph cells.

Schoors, D. F., Vauquelin, G. P., De Vos, H., Smets, G., Velkeniers, B., Vanhaelst, L., ...

1. We studied the lactotroph cells of the rat by both in vivo and in vitro pharmacological techniques for the presence of D1-receptors. Both approaches revealed the presence of D2-receptor,...