Lorca, T, Fesquet, D, Zindy, F, Le Bouffant, F, Cerruti, M, Brechot, C, ...
Inhibition of okadaic acid-sensitive phosphatases released the cyclin degradation pathway from its inhibited state in extracts prepared from unfertilized Xenopus eggs arrested at the second meiotic...
Devault, A, Martinez, A M, Fesquet, D, Labbé, J C, Morin, N, Tassan, J P, ...
The kinase responsible for Thr161-Thr160 phosphorylation and activation of cdc2/cdk2 (CAK:cdk-activating kinase) has been shown previously to comprise at least two subunits, cdk7 and cyclin H. An...
Labbé, J C, Martinez, A M, Fesquet, D, Capony, J P, Darbon, J M, Derancourt, J, ...
p40MO15, a cdc2-related protein, is the catalytic subunit of the kinase (CAK, cdk-activating kinase) responsible for Thr161/Thr160 phosphorylation and activation of cdk1/cdk2. We have found that...
Fesquet, D, Labbé, J C, Derancourt, J, Capony, J P, Galas, S, Girard, F, ...
Phosphorylation of Thr161, a residue conserved in all members of the cdc2 family, has been reported to be absolutely required for the catalytic activity of cdc2, the major regulator of eukaryotic...
Lorca, T, Galas, S, Fesquet, D, Devault, A, Cavadore, J C, Dorée, M
Exit from M phase, which requires cyclin degradation, is prevented from occurring in unfertilized eggs of vertebrates arrested at second meiotic metaphase due to a cytostatic factor recently...
Lorca, T, Labbé, J C, Devault, A, Fesquet, D, Capony, J P, Cavadore, J C, ...
Exit from metaphase of the cell cycle requires inactivation of MPF, a stoichiometric complex between the cdc2 catalytic and the cyclin B regulatory subunits, as well as that of cyclin A-cdc2 kinase....
Budding yeast RSI1/APC2, a novel gene necessary for initiation of anaphase, encodes an APC subunit.
Kramer, K M, Fesquet, D, Johnson, A L, Johnston, L H
SIC1 is a non-essential gene encoding a CDK inhibitor of Cdc28-Clb kinase activity. Sic1p is involved in both mitotic exit and the timing of DNA synthesis. To identify other genes involved in...
A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.
Fesquet, D, Fitzpatrick, P J, Johnson, A L, Kramer, K M, Toyn, J H, Johnston, L H
Exit from mitosis in all eukaroytes requires inactivation of the mitotic kinase. This occurs principally by ubiquitin-mediated proteolysis of the cyclin subunit controlled by the anaphase-promoting...
Lorca, T, Fesquet, D, Zindy, F, Le Bouffant, F, Cerruti, M, Brechot, C, ...
Inhibition of okadaic acid-sensitive phosphatases released the cyclin degradation pathway from its inhibited state in extracts prepared from unfertilized Xenopus eggs arrested at the second meiotic...
Devault, A, Martinez, A M, Fesquet, D, Labbé, J C, Morin, N, Tassan, J P, ...
The kinase responsible for Thr161-Thr160 phosphorylation and activation of cdc2/cdk2 (CAK:cdk-activating kinase) has been shown previously to comprise at least two subunits, cdk7 and cyclin H. An...
Labbé, J C, Martinez, A M, Fesquet, D, Capony, J P, Darbon, J M, Derancourt, J, ...
p40MO15, a cdc2-related protein, is the catalytic subunit of the kinase (CAK, cdk-activating kinase) responsible for Thr161/Thr160 phosphorylation and activation of cdk1/cdk2. We have found that...
Fesquet, D, Labbé, J C, Derancourt, J, Capony, J P, Galas, S, Girard, F, ...
Phosphorylation of Thr161, a residue conserved in all members of the cdc2 family, has been reported to be absolutely required for the catalytic activity of cdc2, the major regulator of eukaryotic...
Lorca, T, Galas, S, Fesquet, D, Devault, A, Cavadore, J C, Dorée, M
Exit from M phase, which requires cyclin degradation, is prevented from occurring in unfertilized eggs of vertebrates arrested at second meiotic metaphase due to a cytostatic factor recently...
Lorca, T, Labbé, J C, Devault, A, Fesquet, D, Capony, J P, Cavadore, J C, ...
Exit from metaphase of the cell cycle requires inactivation of MPF, a stoichiometric complex between the cdc2 catalytic and the cyclin B regulatory subunits, as well as that of cyclin A-cdc2 kinase....
Budding yeast RSI1/APC2, a novel gene necessary for initiation of anaphase, encodes an APC subunit.
Kramer, K M, Fesquet, D, Johnson, A L, Johnston, L H
SIC1 is a non-essential gene encoding a CDK inhibitor of Cdc28-Clb kinase activity. Sic1p is involved in both mitotic exit and the timing of DNA synthesis. To identify other genes involved in...
A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.
Fesquet, D, Fitzpatrick, P J, Johnson, A L, Kramer, K M, Toyn, J H, Johnston, L H
Exit from mitosis in all eukaroytes requires inactivation of the mitotic kinase. This occurs principally by ubiquitin-mediated proteolysis of the cyclin subunit controlled by the anaphase-promoting...