Early detection of rifampin in human nerve tissue after an oral dose of 600 milligrams.
Guebre-Xabier, M, Shannon, E J, Kazen, R, Kebret, Z, Frommel, D
Rifampin in picogram quantities inhibited the ability of Mycobacterium bovis 44 BCG P3 to release 14CO2 from the oxidation of [14C]palmitic acid. By using these mycobacteria in a bioassay, samples of...
Beimnet, K, Söderström, K, Jindal, S, Grönberg, A, Frommel, D, Kiessling, R
Monocytic cell lines (HL-60 and THP-1) were infected with viable Mycobacterium leprae. Levels of human hsp60 were estimated by Western blot (immunoblot) assay and a sandwich enzyme-linked...
Vaccine-induced immunity against cutaneous leishmaniasis in BALB/c mice.
Frommel, D, Ogunkolade, B W, Vouldoukis, I, Monjour, L
Partially purified antigens, derived from Leishmania infantum or L. major promastigotes and isolated under reducing conditions, were used to immunize BALB/c mice. Three subcutaneous injections of the...
Conformational Significance of the Intrachain Disulfide Linkages in Immunoglobulins
Litman, G. W., Good, R. A., Frommel, D., Rosenberg, A.
Biophysical studies of intact immunoglobulins, enzymatically derived immunoglobulin subunits, and chemically derived immunoglobulin chains are reported. All the forms studied lacked optical activity...
Early detection of rifampin in human nerve tissue after an oral dose of 600 milligrams.
Guebre-Xabier, M, Shannon, E J, Kazen, R, Kebret, Z, Frommel, D
Rifampin in picogram quantities inhibited the ability of Mycobacterium bovis 44 BCG P3 to release 14CO2 from the oxidation of [14C]palmitic acid. By using these mycobacteria in a bioassay, samples of...
Beimnet, K, Söderström, K, Jindal, S, Grönberg, A, Frommel, D, Kiessling, R
Monocytic cell lines (HL-60 and THP-1) were infected with viable Mycobacterium leprae. Levels of human hsp60 were estimated by Western blot (immunoblot) assay and a sandwich enzyme-linked...
Vaccine-induced immunity against cutaneous leishmaniasis in BALB/c mice.
Frommel, D, Ogunkolade, B W, Vouldoukis, I, Monjour, L
Partially purified antigens, derived from Leishmania infantum or L. major promastigotes and isolated under reducing conditions, were used to immunize BALB/c mice. Three subcutaneous injections of the...
Conformational Significance of the Intrachain Disulfide Linkages in Immunoglobulins
Litman, G. W., Good, R. A., Frommel, D., Rosenberg, A.
Biophysical studies of intact immunoglobulins, enzymatically derived immunoglobulin subunits, and chemically derived immunoglobulin chains are reported. All the forms studied lacked optical activity...
Studies on the mechanism of immunoglobulin binding to red cells
Frommel, D., Grob, P. J., Masouredis, S. P., Isliker, H. C.
The red cell uptake of IgG on the basis of absorption experiments appears to be due to two populations of IgG molecules. One population is readily absorbable by red cells. The quantity of this type...
Interaction of IgG and its fragments with red cells
Grob, P. J., Frommel, D., Isliker, H. C., Masouredis, S. P.
The red cell uptake of 131I following incubation of red cells with [131I] IgG prepared from normal donors was shown to be IgG and not trace contaminants such as transferrin, lipids or iodide. The...
Howe, R C, Wondimu, A, Demissee, A, Frommel, D
In the present study we examined the functional properties of T-cell clones reactive with Mycobacterium leprae and other mycobacterial antigens. Clones isolated from the skin lesions and blood of...
Immunopathologic aspects of woodchuck hepatitis.
Frommel, D., Crevat, D., Vitvitsky, L., Pichoud, C., Hantz, O., Chevalier, M., ...
The natural history of infection with woodchuck hepatitis virus (WHV) has been studied in a colony of 38 Marmota monax. Besides serologic assessment for WHV markers, light-microscopic findings of 61...
LOCALIZATION OF IMMUNOLOGICAL COMPLEXES FIXING β1C (C3) IN GERMINAL CENTERS OF LYMPH NODES
Gajl-Peczalska, K. J., Fish, A. J., Meuwissen, H. J., Frommel, D., Good, R. A.
28 human and 60 experimentally stimulated rabbit lymph nodes were studied by means of light microscopy and immunofluorescence. 21 of the 28 human lymph nodes showed well-developed germinal centers....